Sentences with phrase «cytochrome c loss»
All of this damage damages extremely precious mitochondrial DNA, which make the mitochondrias dysfunctional, clogging lysosome for mitophagy, and being incapable of keeping mitochondrial membrane potential (leading to Cytochrome C loss through mitochondrial permeability pores) and mitochondrial ATP OXPHOS respiration.
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Chronic treatment with azide in situ leads to an irreversible loss of cytochrome c oxidase activity via holoenzyme dissociation.