Sentences with phrase «cytoscape pathway analysis»

Program impact pathway analysis of a social franchise model shows potential to improve infant and young child feeding practices in Vietnam

The Moores Cancer Center's Molecular Tumor Board brought together medical, surgical and radiation therapy oncologists, biostatisticians, radiologists, pathologists, clinical geneticists, basic and translational science researchers, and bioinformatics and pathway analysis specialists to discuss the intricacies of tumor genetics and tailor a personalized treatment plan for patients with advanced cancer or who have exhausted standard therapies.

To make BinoX directly usable for other researchers, a public web server http://PathwaX.sbc.su.se (Ogris et al., 2016b) was set up for on - line pathway analysis of single gene sets, which applies the BinoX algorithm to all KEGG pathways and FunCoup networks.

«We believe that our new method will revolutionise the way researchers do pathway analysis and yield many new functional insights.

Pathway analysis also found changes in genes linked to the immune system, the body's inflammatory response, and cells» energy metabolism.

He says the EEG and fMRI techniques «counter each other's weaknesses» in pathway analysis.

That requires analytical and bioinformatics tools to conduct disease or therapeutic association and pathway analysis that combines various forms of «omics data.

A proteomics analysis revealed expression changes of 56 proteins, and a further protein pathway analysis suggested their association with the cell morphology, the organization, and the increased cellular movement and the proliferation.

S2 A and B and S3 A and B) and visualized by Cytoscape pathway analysis (SI Appendix, Fig.

The ECETOC Young Scientist Award at the European Societies of Toxicology (Eurotox) Annual Congress (Rhodes, Greece, 5 - 8 October 2008) went to: Ms Nathalie Lambrecht of CARDAM VITO in Belgium for her poster, entitled «Pathway analysis of dendritic cell markers for skin sensitization.»

Pathway analyses implicate glial cells in schizophrenia.

By the end of 2009, I was involved heavily in pathway analysis of the array data.

PathProt is the international forum for Pathway Analysis in Proteomics.

Functional gene annotation was performed using dammit, Gene Ontology (GO), KOG (WebMGA) and KEGG pathway analyses (Kaas).

A number of fancy clinical - correlation and pathway analyses revealed some interesting patterns of somatic mutations between AI - sensitive and AI - resistant tumors:

To gain biological relevance of methylation differences in adipose tissue from unrelated patients with diabetes versus nondiabetic subjects, we performed a KEGG pathway analysis of the 7,046 genes that exhibit differential methylation at q < 0.15 (Supplementary Table 12) using WebGestalt.

Interestingly, we also found enrichment of differentially methylated genes related to glycan metabolism in the pathway analysis in adipose tissue from unrelated patients with diabetes versus nondiabetic subjects.

Koschmann, J., Bhar, A., Stegmaier, P., Kel, A. E. and Wingender, E. Upstream Analysis: An integrated promoter - pathway analysis approach to causal interpretation of microarray data.

Using these orthogonal measures of cellular pathway analysis, we confirmed that HPP - 4382, in contrast to bardoxolone, did not induce significant cellular stress at high doses as measured by HSPA6 expression and that the mechanism of HPP - 4382 activity does not appear dependent on NF - B as ICAM1 expression is not induced by HPP - 4382 (data not shown).

Pathway analysis revealed that the differentially expressed miRNAs were involved in potential glaucoma pathways, including focal adhesion, tight junctions and TGF - beta signaling.

In addition, we performed a preliminary pathway analysis [12] using these data, to examine the feasibility of this type of tool for future investigations to probe for clues to the pathogenetic mechanisms behind these diseases.

Pathway analysis revealed that cold upregulated pathways involved in energy usage, oxidative phosphorylation, and fatty acid β - oxidation to a similar extent in wildtype and PPARα − / − mice.

193/6: 30 The hunt for rare disease diagnosis: Utilization of social media, model organisms, and pathway analysis in pediatric exome sequencing.

Pathway Analysis of the data was performed with Ingenuity Pathways Analysis (Ingenuity Systems, www.ingenuity.com).

The discovery of many of the same proteins in each proteome is important because it allows comparative pathway analysis, so that useful hypotheses of pathogenesis can be formulated and tested.

Competitive pathway analysis implicated the biological processes of neurogenesis and synaptic regulation, as well as the gene targets of two pharmacologic agents: cinnarizine, a T - type calcium channel blocker, and LY97241, a potassium channel inhibitor.

We first performed pooled sample analysis, then individual sample analysis, and then pathway analysis using the observed proteins.

Illustrative example of pathway analysis with respect to axonal guidance pathways.

We found that the complement cascade related proteins were identified and significantly enriched in both CFS and nPTLS pooled CSF proteomes by the Fisher Exact test (p = 0.005) implemented in Ingenuity Pathways Analysis (Figure S1A).

Illustrative example of pathway analysis with respect to complement pathways.

They whittled a 1,597 gene dataset down to 360 MD suspects, which went through a knowledge - based pathway analysis using IPA.

Integrated pathway analysis implicated the involvement of extracellular matrix degradation, collagen catabolism and angiogenesis in disease progression.

The research employed associational methodology and used Structured Equation Modeling statistics, specifically, Pathways Analysis, to analyze a variety of variables and their relative influence upon mathematics achievement for the fourth - and eighth - grade NAEP scores.

Both have been included in the recent Deep Decarbonization Pathways analysis undertaken by one of the sponsors of today's meeting, the U.N. Sustainable Development Solutions Network.

Dr. Patrinos highlighted advances in genomics, structural biology, pathway analysis, and systems biology as driving forces in the move toward molecule - based cell simulation.

Advaita is the only company in the bioinformatics technology sector that focuses on the pathway analysis rather than data.

All functional analysis was done using Ingenuity Pathway Analysis with the default parameters as it was shown to be a reliable approach to identify biological pathways that influence disease outcomes [52].

Further, in our pathway analyses, we find large impacts on delaying marriage in both countries.

Not exact matches

Lacking a leader, «it's hard for me to be optimistic or pessimistic because I don't know if they're going to open the floodgates and take a lot of risks to rush the technology out — or if they're going to take a reasonable, rational pathway to protecting people,» said David Friedman, director of cars and product policy and analysis at Consumers Union.

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

Only a very small number of companies have set long - term (2030 or later) targets which can be considered to be in line with a sectoral 2 °C pathway.282 An analysis of 70 of the world's largest publicly listed corporate emitters, across the aluminium, cement, chemicals and electric utilities sectors, found that 21 had targets up to 2020 which could be considered consistent with a 2 °C sectoral pathway, but only 7 had targets to 2030 or later.283 Twenty others had non-2 °C or «irrelevant» targets, and the rest had none at all.

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

«Whatever pathway we choose to a low - carbon future, it's absolutely clear from the government's analysis that we have to go beyond oil in our transport system.

«Our analysis shows that the galactic cosmic rays, which are charged particles energetic enough to penetrate below the lunar surface, can dissociate the water, H2O, into H2 through various potential pathways.»

Analysis of signaling pathways that were affected pointed to changes in mitochondrial function and oxidative phosphorylation, consistent with a number of studies showing perturbations of these pathways in neurodegenerative disorders.

Los Alamos National Laboratory conducts a wide range of biological research efforts as part of its national security science mission, with such research as phylogenetic analysis helping to determine safe pathogens and disease transmission pathways.?

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

This analysis produced networks that mapped out how alpha - synuclein is related to other Parkinson's genes through well - defined molecular pathways.

«Our goal is to provide objective, data - driven analysis to help inform policymakers in California and elsewhere about which technology pathway is likely to be more cost - effective in combating climate change,» Pellow said.

To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.