«Down to the quantum dot: Ultrahigh - resolution 3 -
D microscopy technique for electric fields.»
Not exact matches
Forthcoming workshops cover
techniques as varied as «molecular and genetic tools for the analysis of medaka and zebrafish development» and «cryo - electron
microscopy and 3 -
D image reconstruction.»
«At the very microscopic level,» he says, «we
have developed
techniques like two - photon
microscopy, which allows extremely detailed examinations of structures and processes within cells.»
Over the last half - century, protein structure data from imaging
techniques like X-ray diffraction and electron
microscopy has mounted, and protein structure databases store at - the - ready information on sequencing and structure.
Scientists
would then be able to look at the slices with
microscopy and other
techniques to learn precisely what the brain looked like, right down to the cellular level.
This achievement
has been made possible by using high - resolution cryo - electron
microscopy, a
technique brought to the CNIO thanks to Óscar Llorca, director of the Structural Biology Programme and lead author on the paper published in Nature Communications.
COOL ADVANCE Cryo - electron
microscopy, an imaging
technique that involves flash freezing molecules to see their structures,
has won its inventors the Nobel Prize in chemistry.
An X-ray
microscopy technique recently developed at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab)
has given scientists the ability to image nanoscale changes inside lithium - ion battery particles as they charge and discharge.
Backman
has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical
technique he pioneered called partial wave spectroscopic (PWS)
microscopy.
The researchers
have also been able to couple their new meso - level imaging
technique with extremely detailed electron
microscopy.
«Advances in imaging
techniques, such as 2 - photon
microscopy,
have allowed us to observe the adhesion process and characterise the two components.
This work, with the assistance of soil scientists at the University of KwaZulu - Natal,
has involved a suite of
techniques, including x-ray fluorescence (to provide quantitative data on minor and trace element composition), x-ray diffraction (to reveal crystal structure and parent rock types of paint ingredients), and environmental scanning electron
microscopy (to yield qualitative data on elements present).
Much like in an old tube television where a beam of electrons moves over a phosphor screen to create images, the new
microscopy technique works by scanning a beam of electrons over a sample that
has been coated with specially engineered quantum dots.
«We studied a range of authentic microfossils using the same transmission electron
microscopy technique and in all cases these reveal coherent, rounded envelopes of carbon
having dimensions consistent with their origin from cell walls and sheaths.
Two research teams
have independently developed light
microscopy techniques that resolve objects on the nanometer scale, one of which is described online in Science this week (www.sciencemag.org/cgi/content/abstract/1127344).
The new
technique, dubbed photoactivated localization
microscopy, currently
has a resolution similar to that of electron
microscopy.
It's not reruns of «The Jetsons,» but researchers working at the National Institute of Standards and Technology (NIST)
have developed a new
microscopy technique that uses a process similar to how an old tube television produces a picture — cathodoluminescence — to image nanoscale features.
Cancer Virus made me reflect on just how quickly biology
has progressed: in the 1960s, electron
microscopy was in its infancy, and DNA - based
techniques for characterising what might be lurking in tissue simply didn't exist.
Furthermore, so as to understand the chemical and physical nature of the shaping process, standard characterization
techniques (spectroscopy and electron
microscopy)
have been employed, as well as new theoretical models and advanced computer simulation
techniques.
To find answers, Columbia researchers developed a new
microscopy technique that allows for the direct tracking of fatty acids after they
've been absorbed into living cells.
Although SIM and other superresolution
techniques are pushing to spatial resolutions as high as 20 nanometers, they do not
have the field of view of a
technique like Bessel beam
microscopy; they can only see a very small area, and imaging a larger area with those
techniques takes a long time.
A team led by Professor Theo Lasser, the head of the Laboratory of Biomedical Optics (LOB) at EPFL
has now made strides to address the issue by developing a
technique that can perform both 3D super-resolution
microscopy and fast 3D phase imaging in a single instrument.
But now, using a
technique called structured illumination, the EMBL team
has managed to subtract out this interference, making light sheet
microscopy even more powerful.
Because cement is a heterogeneous material, made up of multiple components, Shahrin used a scanning electron
microscopy / X-ray
technique to find the areas in cement samples that
had the highest ratio of C - S - H relative to other constituent materials.
To determine the structural and chemical composition of the soft tissues Lindgren collected and see if the fossil sea turtle did
have a dark colored shell, the researchers subjected the sample to a selection of high - resolution analytical
techniques, including field emission gun scanning electron
microscopy (FEG - SEM), transmission electron
microscopy (TEM), in situ immunohistochemistry, time - of - flight secondary ion mass spectrometry (ToF - SIMS), and infrared (IR) microspectroscopy.
Her team's research opens up new possibilities in the nascent field of 3 -
D nanomagnetics, which
has evolved through recent discoveries of new magnetic effects at the atomic level, as well as advances in characterization methods such as in the X-ray magnetic
microscopy technique used by the group.
Certain
microscopy techniques would reveal only the particles, while others
would distort the 3D structures.
The team
has succeeded not only in deciphering what is happening in the cell interior but also, using a revolutionary live - cell
microscopy technique, the scientists
have observed for the first time individual receptors at work in intact cells.
She and her research group recently demonstrated CLAIRE's imaging capabilities by applying the
technique to aluminum nanostructures and polymer films that could not
have been directly imaged with electron
microscopy.
Scientists at Albert Einstein College of Medicine of Yeshiva University and their international collaborators
have developed a novel fluorescence
microscopy technique that for the first time shows where and when proteins are produced.
A new
technique enables 3 -
D visualization of chromatin (DNA plus associated proteins) structure and organization within a cell nucleus (purple, bottom left) by painting the chromatin with a metal cast and imaging it with electron
microscopy (EM).
Schopf used several
techniques to analyze the fossils, including Raman spectroscopy — which enables scientists to look inside rocks to determine their composition and chemistry — and confocal laser scanning
microscopy — which renders fossils in 3 -
D.
By parsing the cells with slices of laser light and then correcting for any obstruction with the same AO
technique astronomers use to correct blurriness in observations of stars, the scientists
have come up with a
microscopy technique that looks like an artistic rendering.
If you question whether
microscopy really should be considered part of the future of diffraction, let me point out that many of the algorithms and other
techniques for turning collections of cryoEM images into three - dimensional structures
had their origins in X-ray diffraction.
She
has extensive research experience in the development and application of novel electron
microscopy techniques for energy materials, such as lithium ion battery materials and fuel cell catalysts.
Scientists
have combined robotic
techniques with atomic force
microscopy to achieve understanding of how skin falls apart at the nanoscale.
We
have studied the mechanism of RSC - induced chromatin remodeling by using high resolution
microscopy and state of the art biochemistry
techniques.
The invention of atomic force
microscopy has spawned a wide variety of measurement and manipulation
techniques invaluable for many purposes.
For this latest study of DNA nanostructures, Ren used an electron - beam study
technique called cryo - electron
microscopy (cryo - EM) to examine frozen DNA - nanogold samples, and used IPET to reconstruct 3 -
D images from samples stained with heavy metal salts.
In another demonstration of the ripple effect created by a single, RPB - supported investigation, researchers, using a new
microscopy technique focused on eye tissues damaged by scarring in diabetic patients,
have...
To celebrate the 30th anniversary of the Nobel Prize in scanning tunnelling
microscopy (STM) and the 30th anniversary since the first paper in atomic force
microscopy (AFM), Nanotechnology ™
has been organising a focus collection with guest editors Franz Giessibl, Rodolfo Miranda and Johannes Barthes to collate some of the latest cutting - edge progress developing and exploiting these scanning probe
techniques.
Recently, researchers figured out a way to modify a popular electron
microscopy technique to look at a mix of materials, even those that
would appear invisible to standard imaging
techniques.
Similar to light
microscopy, there
have been significant advances in tissue clearing
techniques during this century.
Although the modern explosion in light
microscopy techniques has provided biologists with a host of tools and opened doors to many great insights, it can be overwhelming to a novice microscopist.
Due to its unrivaled contrast, fluorescence imaging
has emerged as the dominant light
microscopy contrast
technique in modern biology (1).
Recent progress in phylogenomics, and the implementation of modern molecular,
microscopy, and cell biology
techniques in a handful of spiralian model systems
have made that possible.
Compared to previous years, the course
has an updated program of lectures involving the latest
microscopy imaging
techniques, such as super-resolution light
microscopy (SIM / PALM, STED, STORM) or Atomic Force
Microscopy (AFM).
«For more than a hundred years it was thought that there was a physical limit to the resolution of
microscopy but these
techniques have pushed that limit far beyond what anyone thought possible.
The team
has systematically validated the fidelity, accuracy, reliability, reproducibility and versatility (for many cell types) of this method, using various other
techniques such as confocal
microscopy, flow cytometry, Western blotting and Raman spectroscopy.
Berkeley Lab researchers, working at the Molecular Foundry,
have invented a
technique called «CLAIRE» that extends the incredible resolution of electron
microscopy to the non-invasive nanoscale imaging of soft matter, including biomolecules, liquids, polymers, gels and foams.