Sentences with phrase «dn4 cell ratio»

The cells were stimulated with anti-CD3 / anti-CD28 coated magnetic beads at a 3 ∶ 1 bead to cell ratio [34].

Assays were performed in triplicate using effector to target cell ratios ranging from 50:1 to 200:1.

[2] Sato E, Olson SH, Ahn J, Bundy B, Nishikawa H, Qian F, Jungbluth AA, Frosina D, Gnjatic S, Ambrosone C, Kepner J, Odunsi T, Ritter G, Lele S, Chen YT, Ohtani H, Old LJ, Odunsi K. Intraepithelial CD8 + tumor - infiltrating lymphocytes and a high CD8 + / regulatory T cell ratio are associated with favorable prognosis in ovarian cancer.

Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin - 6.

Compared to WT mice, Itpkb - / - mice had significantly less TCRβ - DN4 and ISP cells, but similar DP cell numbers and an increased (DN3 + DN3 - 4): TCRβ - DN4 cell ratio (Figure 2C).

Not exact matches

Grass - fed Butter contains the ideal ratio of omega 6: omega 3 fatty acids, which is especially important for optimizing cell membrane function and reducing inflammation.

We found that: a) lactation stage must be defined biochemically (such as Na: K ratio), not by day of lactation, b) lactation stage influences RNA quality, quantity, and potential immune cell contamination, c) immediate processing and hard, fast centrifugation yield better quality RNA, and d) additional washing of the milk fat layer is not necessary for the analysis of mature milk samples and does not decrease immune cell contamination in colostrum samples.

The composition of your blood also changes, creating a higher ratio of plasma to red blood cells than in non-pregnant women.

The ratio of inmates to prison officers is growing dangerously vast and the consequence of it is that inmates spend more time cooped up in their cells.

In a study, his team found that female incest survivors had abnormalities in the ratios of immune cells, compared with untraumatised women, exposing them to autoimmune diseases.

«The solar cell industry uses lenses, so the concentration ratio is very limited,» Zhou said.

When added to the cultured cells at molar ratios 103 to 104 times that of the luteinizing hormone releasing factor, both analogs decrease the amount of luteinizing hormone secreted in response to the releasing factor.

Therefore, the researchers analysed the ratio of the inorganic calcite platelets to the organic carbon inside the cells after the adaptation phase.

«The ratio of CD4 and another type of immune cell, CD8, which is often abnormally reversed in HIV, normalized.

Poor overall survival was associated with higher T - cell diversity (that is, higher clone - to - TIL ratios).

The control group had a normal ratio of luminal to basal cells.

As another advantage, APC - mimetic scaffolds enabled us to tune the ratios of subpopulations of T cells with different roles in the desired immune responses, which in the future might increase their functionality,» said David Zhang, the study's second author and a Graduate Student working with Mooney.

The test involves measuring the ratio between the amount of glutamine that a cell takes up from outside and the amount of glutamine it makes internally.

The polygons also can provide information about the depth of the pool of nitrogen through known ratios of width to depth for individual cells of convection, he said.

Monitoring these expression ratios in live cells would provide prospective gene expression data as opposed to traditional retrospective characterization.

That goal is still lower than the conversion ratio achieved by modern cells made from silicon, but organic photovoltaics would be cheaper and could be used in fabrics, plastics and even inks and paints.

The studies demonstrate that nanorods with a high aspect ratio attach more effectively to targeted cells compared with spherical nanoparticles.

«The ratio of two types of immune cells, CD4 and CD8, which are often abnormally reversed in HIV, normalized, and the HIV - resistant cells even migrated to the gut mucosa, an important site for the virus,» Lalezari says.

«With this study, we have demonstrated for the first time that the unfavorable ratio of immune cells already prevailed long before the onset of the disease,» Kaaks says.

The researchers were also able to control the relative composition of different hormonal cell types simply by exposing human pluripotent stem cells to different ratios of two proteins: fibroblast growth factor 8 and bone morphogenetic protein 2.

The DKFZ researchers conducted this study in collaboration with Epiontis, a Berlin - based company that specializes in the epigenetic tests that were used to determine the ratio of the various T cell populations.

Cells may use different rates of translation in different types of mRNA to produce the right amounts and ratios of required proteins.

To find out the specific metabolic pathways affected by disease or stress, the Tufts scientists looked at three parameters: the ratio of FAD to NADH, the fluorescence «fade» of NADH, and the organization of the mitochondria as revealed by the spatial distribution of NADH within a cell (the energy producing «batteries» of the cell).

In situations where ratios become increasingly complex, or the fractions have larger denominators, the mix of cells might be more easily achieved by stochastic means, without basic units.

The example used by Prof. Sinclair is a proportion of cells that is of the ratio 1:3.

If the target ratio for a mix of cells becomes more complex, where the denominator in the fraction is higher, it would become more difficult for a deterministic system to be successful; this is where stochasticity lends itself as an alternative.

A simple repetition of a small group of cells is easily coordinated, and leads to simple ratios of cell types.

Additional analyses revealed that stem cells were also smaller, had a higher nucleus - to - cytoplasm ratio, and were less viscous than mature cells.

Cancer cells contain a higher ratio of DNA to protein and a larger nucleus, making it possible to judge whether cancer is present.

«But then when we do the experiment again and start changing protein levels, the ratio of these cells becomes very different.»

The queen then sought out the larger cells and, on average, laid nearly three times as many drone eggs as usual, apparently making up for the skewed hive gender ratio that resulted from her incarceration, the researchers report in the November / December issue of Behavioural Ecology.

Spalding has been using this ratio to determine the age of teeth in forensic investigations and the turnover rate of fat cells.

Massive transfusion can include adjustments of the ratios of components — including fresh frozen plasma (FFP), platelets and red blood cells (RBC)-- with the goal of improving outcomes.

Caption: An illustration of how cubic titanium nitride with a three - to - four ratio can be synthesized under extreme pressures and temperatures in a laser - heated diamond anvil cell.

Cells were then stimulated with 1 ∶ 4 anti-CD3 (clone FN - 18) / anti-CD28 (clone L293) M - 450 tosylactivated beads (Invitrogen) at a ratio of 1 bead per cell [35], [36].

This affects the ratio of ORGs to other types of cells.

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The expression patterns of cell class - specific markers in mosaic retinas appeared the same in host and donor derived regions suggesting that donor cells generated all retinal cell classes in approximately normal ratios (Figures 5K — 5N and S2).

The same principle lies behind the powerful and visually spectacular Brainbow cell - labeling technique, in which each labeled cell expresses a unique ratio of three or four distinct colors of fluorescent protein.

«A single dose of D+Q (D: 5 mg kg − 1 body weight and Q: 50 mg kg − 1 by oral gavage here and in the following studies), a drug ratio that was most effective in senescent MEFs (data not shown), reduced SA - βgal + cells (Fig.

Co-culture spheroids of ECs and pericytes were generated in a 1:1 ratio with a total of 3 × 105 injected cells as described below in the section «in vitro sprouting assay».

Unlike other fetal - derived stem cell origin, the amniotic fluid contains cells that arise from the developing fetus, at ratios and from origins that vary throughout pregnancy.

The pharmacokinetic properties of J147 after a single dose of 20 mg / kg in mice show brain levels of about 600 nM at 2 h, over 10-fold above its EC50 in some cell culture neuroprotection assays [7], with a brain to blood ratio of approximately 0.5.

Professor Nagy developed and used centrophenoxine to modify the cell structure of elderly animals by removing lipofuscin build - up and by changing the water and lipid / dry mass ratio to that of younger animals.

Nagy of the University of Debrecen (Hungary)-LSB-...] developed and used centrophenoxine to modify the cell structure of elderly animals by removing lipofuscin build - up and by changing the water and lipid / dry mass ratio to that of younger animals.