When this happens, damages to
DNA accumulate over time, causing cell damage, mutation and eventually, death.
Not exact matches
Aging is a key risk factor for sAML because,
over time, hematopoietic stem cells (which give rise to all other blood cell types)
accumulate DNA mutations and changes in other molecules that put
DNA instructions into action, such as RNA and proteins.
We can now precisely count how many cancer - related
DNA mutations
accumulate in smokers» organs
over time
But, the mitochondrial theory of aging also asserts that free radicals damage mitochondrial
DNA frequently and,
over time, the damage
accumulates.