Sentences with phrase «dna damage would cause»

Prof. Umeda found that inhibiting CDKs even with the absence of DNA damage would cause the Rep - MYB3R accumulation seen with DNA damage and stall the cell cycle before the M phase transition.

Not exact matches

Researchers found that all varieties had protective properties, with the outer layers of the red variety being a particularly rich source of quercetin, and showing significant protection of DNA damage caused by free radicals.
But the chemical has since 1995 been ruled as unsafe in food for human consumption because it is capable of causing damage to one's DNA which can potentially lead to the formation of malignant tumours.
Washington State University researchers have mapped the damage of ultraviolet radiation on individual units of DNA, opening a new avenue in the search for how sunlight causes skin cancer and what might be done to prevent it.
Our body has a system to repair DNA damage (DNA repair mechanism), so why a normal cell turns into a cancer cell and why radiation exposure causes cancer have not been clarified.
«Most antibiotics have their effect, directly or indirectly, by causing damage to bacterial DNA, so finding ways to cripple DNA repair would represent a significant advance in the treatment of resistant infections,» says senior study author Evgeny Nudler, PhD, the Julie Wilson Anderson Professor of Biochemistry, Department of Biochemistry and Molecular Pharmacology, NYU Langone.
Fanconi is caused by any one of eight defects in human chromosomes, six of which had been pinpointed to proteins that flock together to help repair damaged DNA.
As part of the international EU project «SPICE II Plus,» which is now coming to an end, scientists from the MedUni Vienna's Institute for Cancer Research have now also found evidence that synthetic substances damage the DNA of human cells and can therefore possibly have cancer - causing effects.
Together, Escherichia coli and Bacteroides fragilis cause DNA damage that could lead to cancer - causing mutations, although this hasn't been seen in people yet.
Previous research has suggested that alcohol can cause carcinogenesis as the ethanol in alcohol metabolizes into acetaldehyde, which damages DNA and prevents DNA repair.
Biologists have generally assumed that the damage will be proportional to the dose, but in vitro studies have shown that cells can repair modest DNA damage caused by radiation — and that low - dose radiation might even protect the cell against future exposure.
Cho said previous research has suggested that alcohol can cause carcinogenesis as the ethanol in alcohol metabolizes into acetaldehyde, which damages DNA and prevents DNA repair.
About 5 % of patients with colorectal cancer that has spread to other organs have a flaw in the genes that repair their tumors» cancer - causing DNA damage.
«We have established that components in thirdhand smoke do cause DNA damage,» said Hang.
A high dose of ActD has been reported to cause DNA damage and suppress transcription from all three classes of RNA polymerases, and ActD at a low dose has been reported to selectively block RNA poly I - dependent transcription [19].
They've also been shown to help decrease DNA damage by reducing inflammation (the underlying cause of many diseases) and reactive oxygen species.
Free radical damage caused by electron - seeking, highly reactive, oxidative molecules has been identified as the source of many maladies through mechanisms such as inhibition of telomerase, changes to cellular permeability and DNA damage.
Some of these dyes, like Red No. 3, have been found to cause damage to the DNA in human liver cells and to disrupt the function of the thyroid.
They have been characterized as «marauders» in the body for they attack cell membranes and red blood cells and cause damage in DNA / RNA strands, thus triggering mutations in tissue, blood vessels and skin.
Even though there's only 5 milligrams of vitamin C in a small apple, it has the antioxidant equivalent of 1,500 milligrams of vitamin C. I've reviewed before how taking that much vitamin C straight in a supplement might actually have a pro-oxidant effect, and cause DNA damage.
Fact is, toxicological studies of the effects of algae (primarily spirulina) consumption on humans and animals, including feeding as much as 800mg / kg, and replacing up to 60 % of protein intake with algae sources, have shown no toxic effects, and in contrast, algae intake has actually been found to prevent damage caused by toxins that affect the heart, liver, kidneys, neurons, eyes, ovaries, DNA, and testicles.
While it is true that cancer cells may have DNA damage, it is highly unlikely that DNA damage can cause any cell to become cancerous.
DNA damage has been shown to cause cancer and lead to depletion of stem cell pools + it also plays a role in the aging process.
Due to the presence of nourishing phytochemicals, kiwi has the ability to protect the DNA from the oxidative damage caused by the free radicals thereby, reducing the risk of development of associated inflammations and diseases.
Cooked meats in general may cause DNA damage and have been linked with increased breast cancer risk.
Astaxanthin has proved itself as a strong UVB absorber and is able to reduce DNA damage that causes cell and collagen degradation in the human skin, which can result in premature aging, hyperpigmentation, wrinkle formation, erythema, and skin cancer.
«The risk factor we have identified is in a gene known to repair UV - caused damage to DNA,» said Dr. Bellone.
Aguayo told TreeHugger that in studies of human cell cultures, potassium bromate has been seen to have a genotoxic effect, or in other words, causes damage to the cell's DNA.
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