BIOHM's Gut Report will show consumers exactly which microorganisms are in their gut through
our DNA deep sequencing analysis of your microbiome (your body's native eco-system made of microorganisms).
Using sophisticated statistical analysis of the massive «
DNA deep sequencing» data enabled the team to trace the evolutionary forces that shaped these natural Synechococcus populations.
Not exact matches
Frey likens
Deep Genomics» technology to a Google search for genetic mutations: researchers can query a
DNA sequence, and the system will identify mutations and tell them what's going to happen and and why it might cause a certain disease.
For example, if founders have established a company to tackle problems related to
DNA sequencing yet prior experience is in social media, a
deeper look into the team's motivations and understanding of its target market would be warranted.
Age - related variations in
DNA methylation were analyzed by
deep sequencing technology, which revealed distinct patterns, with gains in methylation in older individuals occurring at genomic sites that were unmethylated in young individuals, and vice versa.
Researchers
sequenced nuclear
DNA from three molars from layer 11 and a child's molar from a
deeper layer, 22, according to a talk by graduate student Viviane Slon, who works in the lab of paleogeneticist Svante Pääbo at the Max Planck Institute for Evolutionary Anthropology.
Using mass
DNA sequencing, he recently identified resistance genes even in bacteria in pristine permafrost and
deep caves.
In this study that used
deep DNA sequencing of bacterial specific genes, the guts of both males and females exposed to lead had all of the similar complexity in microbiota as those not exposed.
Described in the January 7th issue of Neuron, the technique uses «
deep,» highly sensitive whole - genome
sequencing of single neurons and a new technology that identifies inserted bits of
DNA caused by retrotransposons, one of several kinds of so - called somatic mutations that can arise as the brain develops.
That began to change last year with the discovery of
DNA sequences for an organism that no one has ever actually seen living near a
deep - sea vent on the ocean floor.
The researchers got around that problem by using
deep, next - generation
DNA sequencing, allowing them to pick up on even the smallest changes.
Understanding how a particular
DNA sequence gives rise to a particular protein provides us with some insight into that protein, but a
deeper investigation of how the protein is made, where it is located, and how much of it is present in different cell types is required to enable a true understanding of its function.
This study was based on
DNA sequence and
deep phenotypic data from the Simons Simplex Collection, a set of 2,760 families that have a single child affected by ASD.
Piero Carninci at the RIKEN Yokohama Institute's Omics Science Center in Japan, and colleagues, combined powerful computer modelling with «
deep sequencing» — a process which decodes huge numbers of
DNA sequences to discover...
The technique, called ultra-rapid
deep sequencing, combines
deep sequencing — an emerging technology that reconstructs an entire
DNA sequence from a tiny snippet of
DNA — with advanced computational techniques and algorithms developed in the laboratories of Chiu and his research collaborators.
«Our combined analysis of cell - free
DNA and white blood cell
DNA allows for identification of tumor
DNA with much higher sensitivity, and
deep sequencing also helps us find those rare tumor
DNA fragments.»
To facilitate whole - genome
sequencing of TMAdV, we prepared amplified cDNA /
DNA libraries for
deep sequencing from lung tissue and a lung swab sample from 2 different monkeys using previously published protocols [23], [52].
Our approach uses metagenomic
DNA to construct large ‐ scale heterologous expression libraries that are tracked over time in vivo by
deep sequencing and computational methods.
For one thing,
sequencing technologies continue to develop at a breakneck pace, and, according to Willerslev, as third - generation technologies such as nanopore
sequencing are applied to ancient -
DNA work, researchers will be able to probe even
deeper into the biological past.
Justin Kinney
Sequence - function relationships; biophysics;
deep sequencing; machine learning; transcriptional regulation;
DNA replication
These individuals had already been
deep sequenced with Illumina technology, both for variant calling and estimation of
DNA methylation based on treatment with bisulphite.
Sequencing: Deep DNA sequencing helps determine which mutations are driving a patient's cancer and should be
Sequencing:
Deep DNA sequencing helps determine which mutations are driving a patient's cancer and should be
sequencing helps determine which mutations are driving a patient's cancer and should be targeted.
Unlike profiling strategies involving whole or partial genome
sequencing of mitochondrial
DNA [55], [56], here the ∼ 16.5 kb mitochondrial genome is assembled from only RNA - derived
deep sequencing reads.
Deep Sequencing: Intra-Terrestrial Metagenomics Illustrates The Potential Of Off - Grid Nanopore
DNA Sequencing
We then expanded the project to the other two sites, from which we screened many more samples than we could
sequence deeply, so we selected the best four samples (with highest complexity and endogenous
DNA) from Oakington and the best from Linton (from which we had fewer samples, and there was only one sample with acceptable complexity for
deep sequencing).
ChIP - Seq (ChIP followed by
deep sequencing of
DNA) is an extension of ChIP technology to determine the chromatin enrichment of a transcription factor on a genome - wide scale.
For example, by
deep sequencing bacterial
DNAs from diseased and healthy subjects, the inventors propose that features associated with certain microbiome compositional and / or functional features (e.g., the amount of certain bacteria and / or bacterial
sequences corresponding to certain genetic pathways) can be used to predict the presence or absence of an autoimmune condition.
Highlights of Relevant Experience: Managed matrix team of U.S. and U.K. scientists in first ever large - scale use of US
DNA TAP Store integrated liquid handling capabilities to support
deep sequencing technology project to generate data for genetic rare variants and for potential asset realignment with project delivery of more than 12,000 samples prepared under extremely tight time lines for GlaxoSmithKline.