Sentences with phrase «dna leading to cell death»

Basically the cells are under so much stress that there main protective shield (GSH) gets worn down and oxidative stress damages the mitochondria and the DNA leading to cell death.

Not exact matches

When this level was high enough, stress signals can lead to DNA damage and then trigger a form of cell death called parthanatos.

The fibers are thought to do so by skewering cells, setting off chemical reactions that lead to inflammation, DNA damage and cell death.

Left unrepaired, these DNA lesions could lead to induction of senescence, cell death or mutations, which could be responsible for the development of cancer, neurodegeneration and several other diseases.

Similar to the physical and cellular burn of exercise that creates some oxidizing free radicals, the «stress» from cruciferous vegetables stimulates our mitochondria to produce homemade antioxidants to counterbalance the oxidation and protect our vital DNA.28 Even cancer cells have caught on to this central role of our mitochondria — the bastards can amplify their levels of some of these same pathways — further stressing their importance for survival.25 However, our cells still seem to have the upper hand, as multiple studies show that the organosulfur chemicals in many of these anticancer vegetables can severely stress cancer cells, leading to oxidative damage, and ultimately, death.29