Sentences with phrase «dna library screened»

The higher production efficiencies gained by ALiCE ™ will make it possible for biopharmaceutical researchers to detect a significantly higher number of candidates from each DNA library screened, eventually leading to a higher number of viable candidates for development.

Not exact matches

A new technique of direct binding of radioactive DNA was used to screen a complementary DNA expression library from the BJAB cell line in lambda gt11 phage to derive molecular cDNA clones representing a putative B lymphocyte - specific octamer binding protein.

Recently, GlaxoSmithKline isolated an RIPK2 inhibitor, GSK - 583 (6 -(tert - butylsulfonyl)- N -(5 - fluoro - 1H - indazol -3-yl) quinolin -4-amine), based on using the full RIPK2 protein to screen a DNA - encoded library collection with a fluorescence polarization — based binding assay as a readout (Haile et al., 2016).

The 23 libraries treated with damage repair were screened for complexity and endogenous DNA on an Illumina MiSeq platform in Harvard in collaboration with David Reich (Supplementary Table 1).

While cell - free protein expression done today enables protein chemists to quickly produce small amounts of proteins when screening DNA libraries, there is a need for higher protein expression yields.

As for decoding the complete DNA library of embryos, Dr. Louanne Hudgins, who studies prenatal genetic screening and diagnosis at Stanford, says some pregnant patients there say they've already had fertility clinics do that.

We first used in - solution capture method to enrich the DNA library for human mitochondrial DNA fragments5, 23 to screen for samples with sufficient quality for nuclear genome SNP genotyping.