Sentences with phrase «dna on chromosome»

Gene Pairs... With Ellipses2002Plastic pony beads, nylon string, wood, metal, vinyl and cement35 x 25 feet (Installation at Franconia Sculpture Park) Gene Pairs... With Ellipses consists of 23 pairs of suspended bead strands representing each chromosome in the human genome.Proteins of the first 1,000 base pairs of DNA on each chromosome are strung in opaque beads, while proteins of the final 1,000 base pairs in translucent ones.

The researchers spotted a segment of DNA on chromosome 8 that appeared in the colorblind islanders; then they tested another 60 people from Pingelap and nearby islands to narrow the search down further.

Each color below represents DNA on chromosome 2 from an originating parent strain in the Collaborative Cross project, a large panel of inbred mice.

Scientists have searched for the genetic basis of the two syndromes and have tracked most cases of both to defects on the same spot of the human genome, a stretch of DNA on chromosome 15.

Prader - Willi syndrome is caused by a mutation in a father's genes that deletes a chunk of DNA on chromosome 15.

Yet in both syndromes, the genetic flaw — a bit of missing DNA on chromosome 15 — looked the same.

Not exact matches

Doing so keeps the telomeres found on the ends of your DNA strands long and able to protect chromosomes from deterioration.

So, you're not a 100 % sure if they are identical or fraternal then you want to do an amniocentesis on both sacs, on both babies and amniocentesis as everyone knows is drawing some food from the sac and testing the chromosomes, testing the [inaudible] DNA.

Individuals were classified as high risk for Alzheimer's if a DNA test identified the presence of a genetic marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the disease.

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

When the researchers compared the mRNA to a library of DNA sequences taken from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came from a single gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.

Cech was collaborating with the younger professor on research involving telomeres, the DNA - and - protein caps that guard chromosome tips.

A gene is a hereditary unit consisting of DNA that occupies a spot on a chromosome and determines a characteristic in an organism.

Deletion of the fission yeastpot1 + gene has an immediate effect on chromosome stability, causing rapid loss of telomeric DNA and chromosome circularization.

Feinberg focused on a region on chromosome 11, because a handful of affected patients had abnormalities there, such as DNA that was repeated or deleted.

Family Tree DNA's Y chromosome test ($ 119, familytreedna.com) looks for SNPs and small stretches of repeating nucleotides on the Y chromosome that fathers pass on to their sons.

They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood cells); the protective caps are believed to be markers of biological aging, because they shrink over time.

Eventually, analysis of DNA from the Pima suggested that they have variations on certain chromosomes that are linked to fatness.

The most comprehensive of these, published in August by a Stanford team, analyzed men from nine widely spaced populations, covering 10 million bases (DNA letters) on their Y chromosomes.

Most such research focuses on mutations in the DNA of chromosomes within the cellular nucleus.

In March three separate teams announced that they had zeroed in on a DNA sequence on chromosome 1 that carries the gene for complement factor H, a protein involved in regulating inflammation.

After analyzing both scans together for DNA variants associated with differences between when each patient's movement - associated symptoms first appeared and when they would have been expected based on the number of CAG repeats, MGH CHGR investigator and lead author Jong - Min Lee, PhD, identified two locations on chromosome 15 where variants were significantly associated with either early or late symptom onset.

The findings, reported in tomorrow's issue of the Proceedings of the National Academy of Sciences, suggest that disruption of a DNA - tagging system on this chromosome could be responsible for the syndrome.

These two individuals simply had the good fortune of successfully passing on specific portions of their DNA, called the Y chromosome and the mitochondrial genome, through the millennia to most of us, while the corresponding sequences of others have largely died out due to natural selection or a random process called genetic drift.

The first analysis of the ancestry of domestic cattle using DNA on the Y chromosome reveals that Europe may have had home - grown domestication, too.

Using a variety of sequencing and bioinformatics tools, chromosomal imaging and PCR technology, for the first time, they have identified a large chromosomal swap involving two regions on chromosomes 1 and 4, and showed that it prevents the proper reshuffling of its DNA in its progeny.

Standard mapping procedures depend on homing in on informative coding regions in genes and «walking» along the chromosome, past any uninformative repetitive DNA, to the next gene.

As when he worked on the human genome, Venter is relying on a radical technique called shotgun sequencing: He chops up vast amounts of DNA into tiny pieces and then uses sophisticated computer analyzers to piece them back together into intelligible genes and chromosomes.

Previous studies had relied mainly on mitochondrial DNA transmitted through the female line, or DNA from male sex chromosomes.

The DNA analysis used in this study focused on mitochondrial DNA, which is easier to recover from fossils than the DNA in chromosomes, because each cell has thousands of copies of the relatively short mitochondrial DNA sequence.

He and colleagues reported last year in PLOS Genetics that they had tracked another speciation gene that interacts with PRDM9 to a stretch of 4 million DNA bases on the X chromosome.

Biologists and informatics experts are launching a quiet revolution aimed at building better genomes, one made possible by newer sequencing technologies, novel methods for locating sequences on chromosomes, and improved software for piecing DNA together.

Venken first sought a vector that could handle large amounts of DNA efficiently, settling on a bacterial artificial chromosome, which was designed a couple years ago and is known to maintain only a few copies of the DNA (though it can produce a high number of copies if it is induced).

To better understand how the process works, they focused on the large mobile DNAs, such as plasmids, which exist as free DNA circles apart from the bacterial chromosome, and genomic islands, which can splice themselves into the chromosome.

The offshore bird's secret, revealed for the first time in May by zoologists at Iowa State University, is in the storm petrel's telomeres, repetitive bits of DNA that sit on the ends of the chromosomes in each cell like protective caps.

The finding fits with earlier studies that have found that although living Asians and Europeans have inherited 1 % to 3 % of their DNA from their ancestors» interbreeding with Neandertals, they are missing chunks of Neandertal DNA on their Y chromosomes.

If Reich were to find an unusually low amount of Neanderthal DNA on the X chromosome compared with the other chromosomes, it might be a clue that Neanderthal males impregnated human females.

Even though Neandertals and modern humans interbred several times in the past 100,000 years, the DNA on the Y chromosome from a male Neandertal who lived at El Sidrón, Spain, 49,000 years ago has not been passed onto modern humans, researchers report today in The American Journal of Human Genetics.

The DNA that was most different was on chromosome 11, specifically among genes that control the processing of dietary fatty acids into some of the body's building blocks, the researchers report online today in Science.

Cohen expects to have aligned many thousands of DNA fragments, each stored in a megaYAC, in the order they appear on chromosomes.

That's unusual; most microbial genomes consist of a single chromosome, sometimes with some extra genes carried on bits of extraneous DNA called plasmids.

The investigators found a clever way around this dilemma: They looked for DNA found on the male, or Y, chromosome.

Chromosome fragile sites are regions of DNA double strand breaks on human chromosomes.

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

Schizophrenia risk From previous studies, the researchers knew that one of the strongest genetic predictors of people's risk of schizophrenia was found within a region of DNA located on chromosome 6.

During development, chromosomes are subject to chemical changes that don't affect the nucleotide sequence but can turn genes on or off; the best known example is methylation, in which a methyl group is attached to specific DNA regions.

Analyzing the DNA of about 3,500 diagnosed people and nearly 11,000 without the disorder, researchers homed in on a genetic locus — a gene's location on a chromosome — that's involved in the body's metabolic processes and seems to be associated with the disorder.

Furthermore, the cohanim were much more likely to carry a specific variant of another length of DNA found elsewhere on the Y chromosome than their lay counterparts, suggesting that they share a common ancestor who had this genetic signature.

The gene cluster contains an inversion, or a strand of DNA flipped end - to - end, making it impossible for recombined DNA segments to line up properly on the chromosomes and resulting in a hopeless genetic tangle.

Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so - called «off - target» spots on a chromosome, the development of immune cells can lead to cancer in animal models.