Sentences with phrase «dna sequences»

Aedes has many repetitive sequences and transposable elements (sections that can wander freely within the genome), making it difficult to accurately reassemble the entire set of DNA sequences.
Craig Venter, the molecular biologist whose DNA sequences are the focus of an international row over gene patenting, is leaving the US National Institutes of Health.
The DNA sequences don't align, which makes Shapiro and her team confident that what's in the sediment really belonged to a mammoth.
From analysis of protein and DNA sequences in a large number of modern organisms, Trifonov and his colleagues Alexander Berman and Eugene Kolker have discovered what they think is a legacy of this simple form of genetic material.
Comparing the DNA sequences of similarly shaped proteins in various organisms produces a geneaology of all life on earth that matches those created from completely different data sets.
The $ 3.7 million, distributed among eight research teams, will fund model Internet atlases that display everything from the distribution of squids to the DNA sequences of tiny zooplankton.
Jin - Soo Kim, the director of the Center for Genome Engineering at IBS, as well as the professor of the Department of Chemistry at Seoul National University says, «If CRISPR - Cas9 truncates off - target DNA sequences, it might induce unwanted mutations.
«We are unpacking the entire DNA sequences of 50 influential animals then honing in on the genes associated with specific traits in order to capture the best genetics in the Brahman breed,» he said.
Farrell analyzed highly conserved DNA sequences from 115 species of the herbivorous beetle subfamilies, sampling up to six species from each, to create a phylogenetic tree showing the likely evolutionary relationships of today's beetles and when they diverged from common ancestors.
This rule gets a bit muddled up when you start dealing with DNA sequences, and the like, and both the patent office and the courts are having a lot of problems with this at the moment.
Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.
The conundrum has centred on DNA sequences that do not encode proteins, and yet remain identical across a broad range of animals.
The researchers from Queen Mary University of London sequenced the HAS2 gene in thirteen similar or related mammals, combining the data with DNA sequences extracted from 57 published genomes representing all the major mammal groups.
Gai and Falk used the high - performance computer cluster at Loyola's Center for Biomedical Informatics to analyze billions of DNA sequences to identify the gene mutation in the child and her parents.
But critics warn that genetic engineering has a dark side too, and could lead to designer babies or the release of dangerous DNA sequences into the gene pool, with dire environmental consequences.
The weeds are somehow inheriting DNA sequences from their grandparents that neither of their parents possessed — which is supposed to be impossible.
In Class II engagement, Sox9 binds to multiple active enhancer elements through sub-optimal, low - affinity Sox dimeric motifs (DNA sequences), resulting in a high level of transcription of cartilage - related genes.
The DNA sequences were then used to determine the type of bacteria present.
Intact mitochondrial DNA sequences have been reported for Neanderthals and a number of extinct ice - age mammals, but the full promise of fossil DNA has yet to be realised.
«The whole range of DNA sequences revealed in each sample corresponds to a specific DI - CH quality index.
One aspect of gene regulation involves enzymes placing chemical tags or modifications on histone proteins — which control a cell's access to the DNA sequences that make up a gene.
Biologists from the University of Geneva (UNIGE), Switzerland, have succeeded in establishing a water quality index based solely on the DNA sequences of the diatoms present in the samples, without needing to identify each species visually.
The signatures act as a proxy for DNA sequences.
The genetic variation of individual DNA sequences in a population is called its genetic diversity.
They also ruled out other possibilities, including the gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead gene, or closely related DNA sequences providing a template for repairs.
Molecular clocks use the rate at which DNA sequences change to estimate how long ago new species arose, assuming a relatively steady rate of genetic evolution.
The DNA sequences traced by the researchers were chosen because of the unique way they are inherited: the Y chromosome is passed only from father to son, and the mitochondrial genome is passed from a mother to her children.
But if genomics is to fulfil its potential, for example in combating disease, we need to know how much DNA sequences vary between individuals.
Others perform specific tasks by binding to particular DNA sequences, or linking themselves tightly to RNA molecules.
Among them were biologists at the University of Oxford who analyzed the DNA sequences of the viruses in the blood of the infected Libyan children.
Using the genetic data, along with high - quality 3D photographs of the participants» faces, the researchers used an artificial intelligence approach to find small differences in DNA sequences, called SNPs, associated with facial features such as cheekbone height.
As their DNA sequences are very similar, it was difficult to correctly allocate the numerous, decoded DNA sections within the entire genome.
In 2014, the company officially launched the Regeneron Genetics Center, which forms diverse private — public collaborations to gain disease insights and find targets by pairing human DNA sequences with electronic health records.
The team looked at methylation, in which a methyl group is placed onto cytosine in DNA sequences.
The researchers investigated how Suv39h1 employs a positive feedback loop to chemically tag thousands of adjacent histones, thus signaling the cell to stow away these underlying, unnecessary DNA sequences.
Instead of DNA sequences, the team dissected the sequence of jobs held by ERC applicants — those who won grants and those who didn't — after they completed their Ph.D. s.
They processed data relating to genetics, including DNA sequences, and to gene expression, as well as epigenetic features — chemical reactions that influence genome functioning and hence phenotype by activating and deactivating genes.
The need to compare multiple cells» DNA sequences to distinguish genuine genetic variants from artifacts limits some of the potential of single - cell sequencing.
Geneticist Robert Fleischer and historian Alain Touwaide of the Smithsonian Institution identified the remedies by comparing DNA sequences against a reference genetics database.
Now Robert Belshaw at Plymouth University, UK, and Gkikas Magiorkinis at the University of Oxford, who study whether these viral DNA sequences contribute to disease, have found evidence that we do share some of these sections of DNA with our extinct cousins.
In 2012, scientists discovered they could adapt the process to make cuts in specific human DNA sequences.
But Aniket Gore of the US's National Institute of Child Health and Human Development and colleagues haven't found any disabling changes in the DNA sequences of eye development genes in the cavefish.
He participated in a 2010 study that identified DNA sequences from 16 ancient Egyptian royal mummies, including Tutankhamun.
Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: Approximate methods
Therefore, before publication, large data sets (including microarray data, protein or DNA sequences, atomic coordinates or electron microscopy maps for molecular and macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a specific access address must be included in the published paper.
The professional researchers provided DNA sequences for the samples the students collected.
The two proteins have different biochemical properties and recognize different DNA sequences, so these properties create more options for gene - editing,» said Dr. Olson, who holds the Pogue Distinguished Chair in Research on Cardiac Birth Defects, the Robert A. Welch Distinguished Chair in Science, and the Annie and Willie Nelson Professorship in Stem Cell Research.
But origin DNA sequences contain more A and T nucleotides than usual.
Not only has SynBERC set up an open - source system for sharing DNA sequences and the basic components of synthetic biology, but stretches of synthetic DNA can now be ordered over the Internet at relatively low cost.
«We hypothesized that virus - like DNA sequences inherent in our own genomes or the RNA transcripts they produce might be driving the production of interferon and contributing to disease,» said Dr. Crow, chair, Department of Medicine, and Benjamin M. Rosen Chair in Immunology and Inflammation Research at HSS.
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