Findings come from an advanced
DNA sequencing application developed by the lab of University of North Carolina Nobel Laureate Aziz Sancar.
«How life survives: Researchers confirm basic mechanism of DNA repair: Findings come from an advanced
DNA sequencing application.»
Not exact matches
Recovered
DNA is suitable for numerous downstream
applications, including bisulfite
sequencing, NGS, and quantitative PCR.
Droplet - based microfluidics is a tool used in various
applications like cell cultures, chemical synthesis and
DNA sequencing.
As he was finishing his Ph.D., in 2010, the first full Neandertal genome
sequence was released, and he realized his expertise might have an exciting
application in ancient
DNA.
Just as the Human Genome Initiative in the 1990s
sequenced human
DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative
sequence materials for identifying new properties for a variety of
applications.
«There was a major gap for researchers using genomic
DNA sequences to understand the evolution of species complexes,» says Ryan Folk, lead author of a study in a recent issue
Applications in Plant Sciences.
The difficulties are well illustrated by last month's rejection of a patent
application in the US, by the Institutes of Health, for
DNA sequences without knowledge of the function of the gene.
«The nicest thing this paper shows is that the
application of next - generation
sequencing techniques is really going to expand what we can do with ancient
DNA,» says Shapiro.
The entire procedure, including
DNA extraction,
sequencing, and marker analysis, is described in the November issue of
Applications in Plant Sciences.
«This will allow researchers to target an expanded range of sites in a variety of genomes, which will be useful for
applications requiring highly precise targeting of
DNA sequences.»
The company, Human Genome Sciences Inc. (HGS) in Rockville, Maryland, found the gene by
sequencing human
DNA and searching databases for possible genes; it didn't know there was a link to AIDS when it filed a patent
application in 1995.
Moreover, the ability to easily program
sequence - specific
DNA targeting and cleavage by CRISPR - Cas components, as demonstrated for Cas9 and Cpf1, allows for the
application of CRISPR - Cas components as highly effective tools for genetic engineering and gene regulation in a wide range of eukaryotes and prokaryotes.
By now,
applications of artificial life (Alife) are becoming commonplace: Social scientists use «evolutionary» algorithms to explore social interactions, for example, while biologists harness the equations for studying protein folding and lining up
DNA sequences.
Dr. Mardis has research interests in the
application of
DNA sequencing to characterize cancer genomes and transcriptomes, and using these data to support therapeutic decision - making.
The advent of molecular cloning,
DNA sequencing and the many tools of molecular genetics and cell biology has given us sufficient knowledge of the basis for disease and the genes to target, but what has limited the
application of gene therapy has been efficient gene delivery systems.
The
application of next - gen
sequencing to RNA libraries (RNA - Seq), chromatin immunoprecipitates (CHiP - Seq), bisulfite - treated
DNA, and regions of open chromatin (DNAse - Seq) makes it possible to interrogate many aspects of the genome in high - throughput fashion.
This makes many of the desirable
applications of forensic
DNA sequencing a bit more difficult.
We concluded that an expanded Revive & Restore, in partnership with biotech organizations, will be able to offer services that include Genetic Insight (
DNA sequencing and analysis), Biobanking (tissue collection and cell culturing), Advanced Reproductive Services (cloning and germ - line transmission), and Genome Engineering (CRISPR, gene - drive, etc.)
Applications include restoring genetic diversity, augmenting adaptation to climate change, conferring resistance to disease, and extirpating harmful invasive species.
Our products are designed for
sequencing analysis of
DNA in whole genome, whole exome, epigenetics, or amplicon
applications.
BETHESDA, Md., Thurs., Oct. 14, 2004 - The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced it has awarded more than $ 38 million in grants to spur the development of innovative technologies designed to dramatically reduce the cost of
DNA sequencing, a move aimed at broadening the
applications of genomic information in medical research and health care.
Whether identifying rare subclones missed by standard bulk
sequencing, or identifying co-mutation patterns in subclones, Tapestri Single - Cell
DNA Panels can be applied across a wide number of
applications, including hematologic malignancies, solid tumor profiling, and genome editing programs.
DNA sequencing technology is developing fast and as a result more
applications arise.
SciLifeLab welcomes
applications for Swedish research projects based on next generation
DNA sequencing.
Dr. Shendure's research group in Seattle pioneered exome
sequencing and its earliest
applications to gene discovery for Mendelian disorders (e.g. Miller and Kabuki syndrome) and autism; cell - free
DNA diagnostics for cancer and reproductive medicine; massively parallel reporter assays and saturation genome editing; whole organism lineage tracing; and massively parallel molecular profiling of single cells.
SciLifeLab now welcomes
applications for the first national research projects, based on next generation
DNA sequencing.
AGBT provides a forum for exchanging information about the latest advances in
DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad
applications.
As a recognized cornerstone for the genomics research community, AGBT provides an outstanding forum for exchanging information about the latest advances in
DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad
applications.
Next - generation
sequencing involves the
application of glass micro-chip based methods and small - volume liquid handling (microfluidics) to
sequence DNA more quickly and more cheaply than ever before, indeed 1000s times less costly than the technology used to
sequence the first human genome just a few years ago.
Grades: 9 - 12 The Marian Koshland Science Museum of the National Academy of Science presents this site that details several current
applications of
DNA sequencing, from tracking the origin of SARS to criminal forensics.
It is popping in all sorts of industries, from financial
applications to
DNA sequencing.»