They showed an exponential growth in the power of technology, from the speed of
DNA sequencing efforts to the power of computers to the growth of the Internet.
«Intensive
DNA sequencing efforts to find the genetic «drivers» of metastasis, which is what kills patients in up to 80 percent of cases, have thus far been disappointing, to say the least,» he said.
«The problem with this is wasted
DNA sequencing effort.
Not exact matches
Helix makes its best
efforts to perform accurate Genomic
Sequencing and to offer
DNA Products of high quality.
The U.S. National Science Foundation — funded
effort will tap extensive museum collections as much as possible, instead of freshly caught bird samples, and will
sequence about 5000 short pieces of the
DNA, focusing on regions that are very highly conserved among all birds.
Sequencing ancient
DNA is expensive, so it can be hard for new labs to enter the field, but
efforts are underway to develop methods to bring down the cost and make the field more accessible to newcomers.
His first book related the story of how he led a private
effort that raced a government - funded consortium to decipher the
DNA sequence that makes up the human genome.
They enable molecular biologists and geneticists to selectively chop
DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or
sequenced as part of an
effort to map an organism's genetic material.
Even as
sequencing costs decline, such high - throughput
efforts require pooling the
DNA samples.
Their
DNA was the basis of the first
effort to compile a complete Neandertal genetic
sequence, which was published in 2010.
Previous
efforts to
sequence preserved mammoth
DNA were error - prone or yielded insights into only a limited number of genes.
This
effort involves first generating lots of tiny, overlapping bits of
DNA that must be assembled in the right order after their nucleotide
sequences are determined.
At Weill Cornell, Imielinski is participating in the precision oncology
effort, which will
sequence tumor
DNA to match patients to particular therapies.
In this research
effort, scientists conducted
DNA sequencing on more than 500 adults and children with DCM and more than 1,100 healthy controls from several ethnically distinct cohorts to learn about the genetic profile of the disease.
The project also serves as a model for other countries»
efforts to
sequence their people's
DNA for research on personalized medical care, says study leader Kári Stefánsson, deCODE's CEO.
Fifteen teams analyzed nearly 500 patients» tumors for genetic aberrations and
sequenced the protein - coding
DNA of 316 samples — by far the largest cancer
sequencing effort to date.
«
Sequencing efforts miss
DNA crucial to bacteria's disease causing power.»
The award is part of NHGRI's Revolutionary Genome
Sequencing Technologies program, which has award $ 14 million in an effort to enable the everyday use of DNA sequencing technologies by biomedical researchers and health - care
Sequencing Technologies program, which has award $ 14 million in an
effort to enable the everyday use of
DNA sequencing technologies by biomedical researchers and health - care
sequencing technologies by biomedical researchers and health - care providers.
DNA sequencing costs have fallen more than 100-fold over the past decade, fueled in large part by tools, technologies and process improvements developed as part of the successful
effort to
sequence the human genome.
A key strength of the Community Project is that it connects a diverse, global community of researchers to a sophisticated
DNA sequencing and analysis pipeline — a massive infrastructure which took considerable
effort to develop.
«What's important about the maize project,» says W. Richard McCombie, Ph.D., CSHL Professor, co-principal investigator on the maize genome project, and a pioneer in genome
sequencing efforts, «is that it provides a reference
DNA sequence for the most important agricultural crop in the U.S., making it much easier for people to look at the many variants of different strains or «accessions» of maize.»
My research combines theory, computation, and experiment in an
effort to better understand the quantitative relationships between
DNA sequence and biological function.
Now, researchers involved in an international
effort to
sequence the entire genome of Arabidopsis have obtained - for the first time - the complete
DNA sequence of chromosomes from a plant species.
Biology went that route with the launch of the Human Genome Project, the international
effort to determine the
sequence of 6 billion molecular «letters» that make up human
DNA.
Since human
DNA sequences contain sensitive and personally identifiable information there have been great
efforts put into protecting privacy and data security.
Of course with enough time, money and
effort most
DNA sequences can eventually be built; de novo designed mammalian genome - scale synthesis however will require a drop in cost by orders of magnitude together with technology improvements to enable
DNA synthesis without restrictions on
sequence composition.