To take that step, researchers from the Max Planck Institute for Molecular Cell Biology and Genetics and the University of Hamburg's Heinrich Pette Institute for Experimental Virology and Immunology began with the bacterial enzyme Cre recombinase, which exchanges any two pieces of DNA flanked on either end by a certain pattern of nucleotides (
DNA subunits) known as loxP.
A genome consists of only four different nucleotide bases, or
DNA subunits, arranged in a particular sequence.
Craig Venter «s team at the J. Craig Venter Institute in Rockville, Maryland, and San Diego, California, has made a bacterial genome from smaller
DNA subunits and then transplanted the whole thing into another cell.
Not exact matches
The
DNA molecule is an extremely long chain of strictly ordered
subunits, a length of several hundred to several thousand of which is called a gene.
A complementary
DNA clone encoding the alpha
subunit of the adenylate cyclase stimulatory G protein (Gs) was isolated and identified.
Molecular cloning of complementary
DNA for the alpha
subunit of the G protein that stimulates adenylate cyclase
Whether the armamentarium of alternative vaccine candidates presently in the pipeline (including inactivated, live attenuated, chimeric, recombinant,
subunit and
DNA vaccines) will improve efficacy beyond 56 % remains to be established.
In particular, early life would have needed to synthesize nucleotides, the
subunits of RNA and
DNA, in order to reproduce itself.
This piece of
DNA, called the 16S
subunit of ribosomal RNA, does not change quickly over time, however, so it gives a very coarse timeline for the evolution of bacteria.
The gene, called gyrase B, codes for a variable
subunit of the
DNA gyrase protein, which helps
DNA coil and uncoil.
«Telomerase is a unique protein - RNA complex where the protein
subunit uses its RNA component as a template to add identical fragments of
DNA to the end of chromosomes,» said Emmanuel Skordalakes, Ph.D., associate professor in the Gene Expression and Regulation program of Wistar's NCI - designated Cancer Center.
Earlier researchers had detected
subunits of
DNA and RNA, called nucleobases, in the meteorite.
The structure shows that two other exposed surfaces of
DNA - bound TAP, called AR2 and AR3, make protein to protein contacts with the RNA polymerase β
subunit and with sigma.
Genomewide analysis of chromatin marks also suggested that normal interactions between the C - terminus of the Rag2 protein
subunit and a specific chromatin modification helps maintain the fidelity of
DNA target recognition by the enzyme.
Still, says Weiner, there are ways to enhance efficacy, for instance by trying more or different genes or by using a so - called prime - boost strategy, in which the
DNA vaccine is followed by a shot with the protein
subunits themselves.
The telomerase ribonucleoprotein has a phylogenetically divergent RNA
subunit, which contains a short template for telomeric
DNA synthesis.
With just 121 genes (compared with humans» 20,000 to 25,000), the Tremblaya genome is the smallest ever found in an organism that isn't an organelle, a small
subunit within a cell that has a little bit of its own
DNA.
XPD encodes one of the two helicase components of basal transcription /
DNA repair factor IIH (TFIIH), a ten -
subunit, multifunctional complex that is essential for multiple processes, including basal transcription initiation and
DNA damage repair via the nucleotide excision repair (NER) pathway [6,7].
All muscle fibers exhibit complex II immunoreactivity, consistent with the nuclear
DNA - encoded expression pattern of this and all other
subunits of complex II.
The cellular transcription factor NF - kB consists of two
DNA - binding
subunits of 50K and 65K and is believed to play an important role in stimulating transcriptional activation of HIV - 1 in latently infected T - cells
NF - kB / p65
subunit DNA - interaction increase with increase of age in several tissues suggesting as NF - kB inhibition may prevent aging and its related diseases 25.
It was suspected, but not known for certain, that fly as well as mouse Zucchini proteins were nucleases — enzymes that specialize in cleaving bonds between the nucleotide
subunits of nucleic acids (
DNA and RNA).
Nucleolin associates with the human cytomegalovirus
DNA polymerase accessory
subunit UL44 and is necessary for efficient viral replication.
We will also assess whether the findings can be translated to a model of lethal murine malaria using Clone 10 - homologue
DNA and protein
subunit vaccines derived from Plasmodium berghei (ANKA) to induce immunity.
He and his colleagues then documented how it mutated genetic sequences in a small region of just three nucleotides, the
subunits of
DNA.
The p127
Subunit (DDB1) of the UV -
DNA Damage Repair Binding Protein Is Essential for the Targeted Degradation of STAT1 by the V Protein of the Paramyxovirus Simian Virus 5
Nucleotide a
subunit of
DNA or RNA, composed of a base, a phosphate and a sugar molecule.
DNA is composed of individual
subunits which are called genes.
Phylogenetic analysis of the non-pathogenic genus Spiromastix (Onygenaceae) and related onygenalean taxa based on large
subunit ribosomal
DNA sequences.