A research team led by András Simon at Karolinska Institutet have managed to sequence the giant genome of a salamander, containing six times more
DNA than the human genome.
Not exact matches
Research comparing
human and chimpanzee
genomes, published in Nature, found that there are more
than 40 million differences between the two species» base pairs, which are the
DNA building blocks.
«Our study shows that epigenetic drift, which is characterized by gains and losses in
DNA methylation in the
genome over time, occurs more rapidly in mice
than in monkeys and more rapidly in monkeys
than in
humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.
In the last eight years, the field of ancient
DNA research has expanded from just one ancient
human genome to more
than 1,300.
Mitochondria carry only a few genes, but they are so plentiful that it's often easier to find their
DNA than the single full
human genome in a cell's nucleus.
In less
than 1 percent of all adults, the virus can also quietly slip its own
DNA into the
human genome — making it possible for mothers and fathers to pass HHV - 6 to their offspring if these insertions are present in their eggs or sperm.
The Emory team used high density microarrays to probe more
than 900,000 sites across the
human genome to detect structural variation, including deletions or duplications of
DNA.
The work is the fruit of the Innovative Genomics Initiative, a joint effort between UC Berkeley and UCSF that aims to correct
DNA mutations that underlie
human disease using CRISPR - Cas9, a pioneering technology co-developed by scientists at UC Berkeley that has made
genome editing easier and more efficient
than ever before.
At 20 billion bases of
DNA, the newly sequenced
genome of the Norway spruce, a popular Christmas tree in Europe that can reach heights above 30 meters, is six times larger
than the
human genome.
Co-author Andrea Manica, a population geneticist at the University of Cambridge in the United Kingdom, has posted a note online explaining that incompatibility between two software packages used to compare Mota's
genome with the reference
human genome led the software program to simply drop certain
DNA variants, with the result that all living Africans seemed to have inherited more «Eurasian»
DNA than they actually did.
The researchers were searching for archaic
DNA sequences in those
human genomes at frequencies much higher
than would be expected if those genes weren't doing people any good.
At first they could not determine more
than six bases in the replica
DNA, which did not provide enough unique addresses to identify individual genes in the
human genome.
Xu applied the
DNA microarray technique to screen more
than 100,000 genes in the
human genome to find the exact gene regulation pathway.
Faster ways to analyse
DNA will speed up the
human genome project, and will be essential if forensics labs are to handle more
than a fraction of the cases that come their way.
The mouse
genome is about 10 % smaller
than the
human genome, owing to a lower repetitive
DNA content.
Two papers by Langmead and team, Ultrafast and memory - efficient alignment of short
DNA sequences to the
human genome and Fast gapped - read alignment with Bowtie 2, have been cited in more
than 12,000 scientific studies since 2009.
The mouse
genome is 14 percent smaller
than the
human genome and contains about 2.5 billion letters of
DNA.
DNA sequencing costs have fallen more
than 100-fold over the past decade, fueled in large part by tools, technologies and process improvements developed as part of the successful effort to sequence the
human genome.
Here we report a public database of common variation in the
human genome: more
than one million single nucleotide polymorphisms (SNPs) for which accurate and complete genotypes have been obtained in 269
DNA samples from four populations, including ten 500 - kilobase regions in which essentially all information about common
DNA variation has been extracted.
BETHESDA, Md., Thurs., Oct. 14, 2004 - The National
Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced it has awarded more
than $ 38 million in grants to spur the development of innovative technologies designed to dramatically reduce the cost of
DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.
More
than 50 years have passed since Watson and Crick untangled the structure of
DNA and five years have elapsed since scientists finished sequencing the entire
human genome.
The sequence spans 2.3 billion
DNA base - pairs and contains some 32,500 genes, or about one - third more
than the
human genome, according to the team that assembled it over the last four years.
The
human genome contains an estimated 3.2 billion base pairs of
DNA, roughly 25 times more
than Arabidopsis.
Next - generation sequencing involves the application of glass micro-chip based methods and small - volume liquid handling (microfluidics) to sequence
DNA more quickly and more cheaply
than ever before, indeed 1000s times less costly
than the technology used to sequence the first
human genome just a few years ago.
This year's
DNA Day (April 23rd) is generating more publicity
than usual as it coincides with the 10th anniversary of the draft
human genome sequence.