Sentences with phrase «dotatoc imaging agent»

Lantheus Holdings Inc.'s shares are headed for one of their biggest losses since the maker of medical - imaging agents and products went public in June 2015.

Chiu and Kelly were involved in the development of a compound called P53, a key component in an imaging agent called Myoview which went on to generate global...

Test that uses imaging agent to detect protein buildup may get government funding, but only in limited cases

More data are needed to understand its clinical value but, if results are favorable, this imaging agent could play a critical role in the standard of care for prostate cancer.»

Direct positron imaging is a nuclear medicine technique that allows researchers to gain physiological information from radiolabeled imaging agents that bind to targets in the body, which are then imaged with a specialized detector.

In the study, the imaging agent — Ga - 68 prostate - specific membrane antigen (Ga - 68 PSMA)-- used with positron emission tomography and computed tomography (PET / CT), changed management in 44 % more cases than another widely used agent.

The team plans to complete safety testing of the imaging agent during the next three years.

In their current study, described online today in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumors.

An investigational imaging agent, if approved, could one day contribute to patient management by helping clinicians direct biopsies and cancer therapies.

For this study, 10 subjects with Alzheimer's underwent PET following the injection of three radiotracers: fluorine - 18 fluorodeoxyglucose (F - 18 FDG), which images regional metabolic activity; carbon - 11 Pittsburgh compound B (C - 11 PiB), which has an affinity for amyloid plaques; and F - 18 AV - 1451, an emerging imaging agent that binds to tau in the brain.

Another project enabled the first FDA - approved imaging agent that could be used in PET scans of Alzheimer's patients who were still alive.

What makes this technique novel is the accompaniment of an imaging agent known as Ga - 68 DOTATOC, which binds to somatostatin receptors in neuroendocrine cells that use the hormone somatostatin to mediate endocrine function, the release of neurotransmitters and cellular proliferation.

UTMD uses microscopic, gas - filled bubbles that can be paired with viral therapies, therapeutic genes and proteins, and imaging agents.

To bypass this issue, Scott developed a nanocarrier using self - assembled, filament - shaped nanomaterials, which are loaded with a drug or imaging agent.

Results showed that 29 patients» scans revealed strong - binding metastases with a high affinity for the imaging agent.

Specifically, the imaging agents developed in the laboratory for use in fluorescence molecular tomography, are now even being translated into the clinic for human diagnostic applications.

This work confirms the translational potential of a PARP - 1 PET imaging agent and supports future clinical trials to test PARP - 1 expression as a method to stratify patients for PARP inhibitor therapy.

Emerging molecular imaging agents join tumor - seeking antibodies and signaling radioisotopes in one radiopharmaceutical that is injected at the time of imaging in order to track and report active receptors.

18F - AV - 1451 is a brain imaging agent used in PET (Positron Emission Tomography) Scans.

Dr. Sanford, who is both a member of the National Academy of Sciences and recipient of a MacArthur «genius grant,» has designed molecules that can be used to store energy in batteries, serve as new medical imaging agents, convert carbon dioxide into fuels, or serve as pharmaceuticals to treat disease.

Sakuma S, Kumagai H, Shimosato M, Kitamura T, Mohri K, Ikejima T, Hiwatari KI, Koike S, Tobita E, McClure R, Gore JC and Pham W. Toxicity studies of coumarin 6 - encapsulated polystyrene nanosphere conjugated with peanut agglutinin and poly (N - vinylacetamide) as a colonoscopic imaging agent in rats.

She also conducts clinical research evaluating prognosticators of outcome in patients with liver, bile duct and liver tumors and investigates new imaging agents in pancreas and liver cancers.

Reston, VA (Scicasts)-- Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple...

With new imaging agents available for both of these proteins, we will be able to quickly reach proof - of - activity of GAIM's mechanism, which will provide us with a gateway into additional indications,» commented Franz Hefti, President and Chief Operating Officer.

Nanoparticles for the sole use of imaging agents have a much lower return on investment and higher safety requirements than drug delivery systems... -LSB-...]

SEATTLE — An imaging agent discovered by a Washington State University researcher that homes in on prostate cancer will be developed for human clinical trials thanks to a two - year $ 2 million federal Small Business Innovation Research grant.

This includes - but is not limited to - PET / CT, contrast agents for MRI, fMRI, CT and U / S, plus all optical imaging agents.

A cancer imaging agent that was originally developed at Emory was approved on Friday, May 27 by the U.S. Food and Drug Administration.

The SNMMI Clinical Trials Network is dedicated to facilitating the use of ALL imaging agents in multi-center clinical trials of investigational therapeutics.

Studying heparanase - a key enzyme in the development and metastasis of human cancers — scientists unveiled new fluorescent imaging agents that detect enzyme activity in healthy and diseased tissues.

Stanford University medical scientists have developed a novel imaging agent that... Read more

The new imaging agent offers a non-invasive method of detecting infection and monitoring antibiotic therapy.

«A drug, imaging agent or other function can be fused to the meditope and snapped onto any meditope - enabled antibody.»

He was introduced to radiopharmaceutical development as a postdoctoral research associate and then as a staff scientist in the department of radiology at Washington University School of Medicine, where he developed several preclinical imaging agents to study brain tumors, atherosclerosis and Alzheimer's disease.

Dr Kelly was employed by Amersham (a predecessor to the defendant company) in 1985 to head a new research group to work on heart imaging agents in a race with Amersham's main competitor Du Pont.

Not exact matches

In the drive to improve early detection and treatment of cancer, a pair of Toronto scientists has developed a unique technology that combines contrast agents with targeted, long - lasting nano - particles for use in multiple medical imaging platforms.

TSA agents will allow you to walk through the metal detectors instead of the x-ray imaging booth.

For this research, a total of 28 subjects were imaged with a variety of imaging modalities, including standard imaging with computed tomography, magnetic resonance imaging and molecular bone scan (SI); PET with a common radiotracer called fluorodeoxyglucose (FDG - PET); and PET with computed tomography and the agent Zr - 89 IAB2M (IAB2M PET / CT) assessed in escalated doses.

The MPI that uses clinically - approved, iron oxide - based MRI contrast agents is capable of 3D, high - resolution imaging in real time.

A new infrared imaging contrast agent highlights hydroxyapetite (purple), a mineral commonly associated with malignant breast cancer.

New results in animals highlight a major safety concern regarding a class of magnetic resonance imaging (MRI) contrast agents used in millions of patients each year, according to a paper published online by the journal Investigative Radiology.

Prior to their study with this contrast agent, Lu's team had conducted studies to determine its clearance from the body after the imaging, which is essential for safe clinical use.

In addition, therapeutic agents can be developed and tested using imaging technologies that are directly translatable to the clinic.

«Small amounts of gadolinium deposit in certain parts of the brain in people who undergo repeated gadolinium - based contrast agent enhanced exams,» said Vikas Gulani, MD, PhD, Associate Professor of Radiology, Urology, and Biomedical Engineering at Case Western Reserve University School of Medicine, member of the Case Comprehensive Cancer Center, and Director of Magnetic Resonance Imaging at University Hospitals Cleveland Medical Center.

A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (Imaging (SNMMI).

Additionally, minimum requirements for individual providers should include an understanding of radiation safety needed for optimal imaging, exposure protection and knowledge of the use of x-ray contrast agents.

Polarized xenon is also used as a contrast agent to enhance images in experimental magnetic resonance imaging (MRI) of human lungs, but conventional systems for producing and using this gas can be as big as a car.

There are quite a few technical challenges when developing an effective contrasting agent for cellular imaging.

According to the authors, their results provide «an adaptable, quantitative imaging framework to assess two MRI contrast agents simultaneously for a wide variety of imaging applications.»

«The method we developed enables, for the first time, the simultaneous detection of two different MRI contrast agents,» said Chris Flask, PhD, Associate Professor of Radiology, Biomedical Engineering, and Pediatrics, and Director of the Imaging Resource Core at Case Western Reserve University School of Medicine.