Sentences with phrase «dentate granule cells»
Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy.
https://www.intelligent-imaging.com/ Not exact matches
Overstreet - Wadiche and UAB colleagues posed a basic question: Since the number of neurons in the dentate gyrus increases by neurogenesis while the number of neurons in the cortex remains the same, does the brain create additional synapses from the cortical neurons to the new granule cells, or do some cortical neurons transfer their connections from mature granule cells to the new granule cells?
In agreement with predictions from these models, we show that minimal changes in the shape of the environment in which rats are exploring can substantially alter correlated activity patterns among place - modulated granule cells in the dentate gyrus.
When a new granule cell neuron is made in the dentate gyrus, it needs to get «wired in,» by forming synapses, or connections, in order to contribute to circuit function.
We have tested this hypothesis by generating and analyzing a mouse strain that lacks the gene encoding the essential subunit of the N - methyl - d - aspartate (NMDA) receptor NR1, specifically in dentate gyrus granule cells.
These results provide evidence that NMDA receptors in the granule cells of the dentate gyrus play a crucial role in the process of pattern separation.
in fascia dentate, spine density is significantly decreased on dendrites of granule cells; dendritic spines are significantly enlarged; dendritic width is similar to controls
Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity Chavlis, S., Petrantonakis, C.P., Poirazi, P. Hippocampus.
Engin E, Zarnowska ED, Benke D, Tsvetkov E, Sigal M, Keist R, Bolshakov VY, Pearce RA, Rudolph U. Tonic inhibitory control of dentate gyrus granule cells by α5 - containing GABAA receptors reduces memory interference.