Not exact matches
In a new study based on mice, scientists at Lancaster University
found that a
drug that goes after three
diabetes - related targets «significantly reversed the memory deficit» in mice who got the
drug, as measured by their performance in a maze test when compared to mice who didn't get the
drug.
Five
diabetes treatments were among 27 branded
drugs showing price gains of at least 20 percent in typical dosages since the first quarter of 2014, a survey for Bloomberg
found.
My uncle has
diabetes and might have prostate cancer, I
found out today, but instead of changing his diet he will just take
drugs and the conventional therapies and feels horrible.
If a
drug is
found that stops late - stage
diabetes, it would really be a major medical breakthrough!»
Stephanie Stanford of the University of California, San Diego, and her team have
found that giving mice with
diabetes a
drug that affects insulin signalling restores their ability to control their blood sugar levels.
In general, the researchers
found liraglutide 3 mg to have a safety profile that was similar to that
found in previous clinical trials of the
drug in individuals with Type 2
diabetes treated with lower doses.
Nondiabetic obese and overweight people lose more weight, are more likely to reverse prediabetes and are slower to develop type 2
diabetes when they take the
diabetes drug liraglutide in addition to dieting and exercising, a new study
finds.
Earlier this month, a network of researchers supported by the National Eye Institute (NEI)
found that the
drug Lucentis (ranibizumab) can be highly effective for treating proliferative diabetic retinopathy, an eye disease that can occur as a complication of
diabetes.
The
finding suggests that something about
diabetes — or the
drugs used to treat it — might offer protection against migraines.
A team from the University of California, San Francisco and Berkeley - based
drug maker Plexxikon
found that most of the mice manipulated to have Type 1
diabetes no longer had
diabetes symptoms after just a few weeks on either of the two
drugs.
Her goal is to
find drugs that treat
diabetes and obesity by targeting circadian pathways.
«If we can
find a
drug that makes beta cells grow, it could improve blood sugar levels in people with
diabetes,» said Maike Sander, MD, professor in the Department of Pediatrics and Cellular and Molecular Medicine at UC San Diego School of Medicine.
In addition to illuminating how the
drug, amlexanox, reverses obesity,
diabetes and fatty liver disease, the
findings suggest a new pathway for future treatments.
«Our
findings suggest a simple strategy to kill metastatic melanoma — regardless of cell type within the tumor — by combining anticancer
drugs with
diabetes drug,» Herlyn said.
A
drug commonly used to moderate
diabetes that induces fat cell production in the bone marrow was used and was
found to help foster red blood cell production as well as suppress leukemic disease.
«We
found that these slow - growing,
drug - resistant cells are marked by a high rate of metabolism, which makes them susceptible to
diabetes therapeutics.»
Finding ways to use CaSR - directed
drugs also for the treatment of diseases such as
diabetes, Alzheimer's disease and various types of cancer, would be a breakthrough.
One specific
diabetes drug, metformin, has been
found widely in treated wastewater, in naturally occurring water bodies and even in tap water.
The
findings open up new avenues of research into exactly how the brain controls eating, and suggest that
drugs designed to activate or inhibit neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as
diabetes and hypertension.
The
finding, published in the journal Developmental Cell, opens up new possibilities for the development of
drugs that block MCRS1 to treat cancer and
diabetes.
So when Drake and his colleagues measured the RNA levels — a direct link to how much of a gene is being produced — in the genes of 334 mice, he didn't expect to
find more than a few variations that might help explain why males and females have such different rates of cardiovascular disease and
diabetes or why they react differently to certain
drugs.
Clinical trials of GlaxoSmithKline's
diabetes drug Avandia (rosiglitazone) and Merck's anti-inflammatory Vioxx (rofecoxib) revealed an elevated cardiac risk from the
drugs, but relevant
findings were held back from regulators or never published.
The
find could one day lead to
drugs that fight obesity and
diabetes.
Sutherlandia is a supplement commonly taken in Africa to fight symptoms of infection and some chronic diseases, such as
diabetes, but MU researchers
found it may disrupt anti-tuberculosis
drugs.
The study, reported online April 28, 2015, in the Journal of General Internal Medicine, confirms past
findings on the link between the widely prescribed
drugs and
diabetes risk.
Sangwon Kim, Ph.D., of the Johns Hopkins University School of Medicine's Division of Endocrinology,
Diabetes and Metabolism, along with researchers at the University of Pennsylvania, found that laboratory mice that had been exposed to a two - week regimen of nicotine displayed no withdrawal symptoms when given the diabetes drug me
Diabetes and Metabolism, along with researchers at the University of Pennsylvania,
found that laboratory mice that had been exposed to a two - week regimen of nicotine displayed no withdrawal symptoms when given the
diabetes drug me
diabetes drug metformin.
The researchers tested their theory by orally administering a
drug that inhibits DNA - PK and
found that, in addition to preventing weight gain in the mice, the inhibitor
drug boosted mitochondrial content in skeletal muscle, increased aerobic fitness in obese and middle aged mice, and reduced the incidence of obesity and type - 2
diabetes.
What's interesting is that there has been a study looking at people who are on this
drug that
found that some of the people with
diabetes that were taking metformin were actually living longer than their non-diabetic counterparts.
Additionally, the
finding raises a question about potential interactions between anti-cholesterol
drugs and
diabetes.
Its researchers made ground - breaking discoveries, including the
findings that calorie - burning brown fat may remain active in adults and that the generic
drug salsalate is a promising treatment for people with type 2
diabetes.
our stroke research, we will soon be able to
find a gene within the type 2
diabetes locus we have identified and use this gene to identify powerful new
drug targets.»
Now, in a new study in the journal Cancer Cell, Shaw and a team of scientists at the Salk Institute for Biological Studies
found that phenformin, a derivative of the widely - used
diabetes drug metformin, decreased the size of lung tumors in mice and increased the animals» survival.
Salk scientists
found that the
diabetes drug phenformin was effective at reducing tumor size in mice with lung cancer.
11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance
Findings may have important potential for new
drug discoveries in fight against Type 2
diabetes Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrop... More...
Research by Rutgers Cancer Institute of New Jersey
finds that targeting a certain signaling pathway with a
diabetes drug may be a novel prevention and treatment strategy for pancreatic cancer progression.
Founded in 2010 by Drs. Stig K. Hansen and Daniel A. Erlanson, Carmot has built and optimized this powerful platform to identify superior
drugs for validated targets with significant market potential such as GLP - 1R / GIPR for Type 2
diabetes and NEMO / IKK for cancer and inflammation, and which have been refractory to traditional discovery approaches.
Of the top 50
drugs found, 43 are known
diabetes treatments, but they
found seven
drugs that either raise or lower blood glucose as a secondary, off - label effect.
The researchers also
found that the sufferers of Type 2
diabetes improved their sensitivity to insulin by 40 percent after exposure to intermittent cold for 10 days, levels similar to diabetic
drugs.
In the past, other dietary supplements have been
found to be tainted with prescription remedies, including
diabetes drugs, Viagra, and other medications.
More recently, berberine has also been
found to improve insulin sensitivity, support glucose control, and even work as well as the
diabetes drug Metformin.
The researchers
found that berberine performed as well as three well - known
diabetes drugs — metformin, glipizide and rosiglitazone — and also helped to lower LDL cholesterol and triglycerides.
In a pilot study involving 36 patients with type 2
diabetes, researchers
found that three months of treatment with berberine had a similar hypoglycemic effect as the popular
diabetes drug metformin.
A 6 times the increase in the odds ratio for reported pancreatitis cases with these
drugs was
found, in comparison to 4 other
diabetes control therapies.
It has been shown to act as an alpha - amylase inhibitor, which means that it inhibits enzymes that cause starches to break down into glucose A study published in the Journal of Agricultural and Food Chemistry showed that the fruit contains compounds that were
found to be comparable to that of acarbose, a prescription
drug used for type 2
diabetes symptoms.
Other research has
found this condition in individuals with cerebellar ataxia, stiff man syndrome, type I
diabetes,
drug - resistant epilepsy, balance problems and more (16).
For example, an analysis of nearly 24,000 patients with type 2
diabetes found that three
diabetes drugs — glipizide, glyburide, and glimepiride — caused a more than 50 percent greater risk of death compared to another
diabetes drug, Metformin.v The three
drugs are known as sulfonylureas, which work by spurring your body to produce more insulin.
That's what other studies have subsequently
found: non-
drug approaches are superior to
drug - based approaches for
diabetes prevention.
They
found that the higher the dosage of statin
drugs being taken, the greater the
diabetes risk.
Researchers have noted pleasure deficiencies shown on brain scans of a variety of people,
finding that frequent abuse of food or
drugs actually alters the brain, causing it to not light up with dopamine as it once did.Chronic overeating can also lead to
diabetes and predisposes the body toward inflammation, insulin resistance, elevated blood pressure, psychiatric illness, poor digestion, hormone imbalance, and malnutrition.
Consult a Physician before using this product if you have, or have a family history of, including but not limited to Phenylketonuria, high blood pressure, cardiac arrhythmias, heart, liver, kidney, thyroid, or psychiatric disease, pheochromocytoma,
diabetes, asthma, recurrent headaches, anemia, nervousness, anxiety, depression or other psychiatric condition, peptic ulcers, Parkinson's disease, glaucoma, difficulty in urinating, prostate enlargement, or seizure disorder, or if you are using any other dietary supplement or over-the-counter
drug containing ephedrine, pseudo - ephedrine, or phenylpropanolamine (ingredients
found in certain allergy, asthma, cough or cold, and weight control products).