Sentences with phrase «differences in gene expression levels»

Hailing from academia and biotechnology, we aimed to discover differences in gene expression levels between tumors and healthy cells.
The only clue indicating that differences in gene expression level are not the reason for the observed correlation between the recombination rate and the size of introns is that we do not see a comparable pattern when examining the size of exons, the number of exons per gene, and the overall size of proteins.

Not exact matches

The new study, published this month by Molecular Autism in a special issue on sex differences in autism, further shows a stronger correlation between the expression level of RORA and that of genes regulated by RORA in males.
If, for instance, a researcher finds that dozens of genes in a microarray are differentially expressed on a high - fat purified ingredient diet compared to a low - fat GB diet, it is tempting to conclude that gene expression was altered due to the differences in fat levels between the diets.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental cellular processes such as ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a complex system of communication that governs basic cellular activities and coordinates cell actions.
To quantitatively determine differences between the expression levels of these genes in hNSCs and hESCs, we utilized real time RT - PCR.
The ability of these populations to interconvert in vitro combined with their subtle differences in gene expression lead us to ask if there was any functional significance to this low level of PrEn gene expression.
Using 5 % false discovery rate in ANOVA calculation in any of the 3 comparisons (CGR8 vs. E14TG2a vs. R1), there are 137 genes (0.9 % of the analyzed transcripts) that show a 2-fold difference or higher in expression levels among the three lines; 34 of these genes are > 2-fold higher or lower expressed in E14TG2a, 5 in CGR8 and 11 in R1 cells.
We considered a minimum ten fold difference in the expression levels of genes as a relevant criterion for classifying them as high and low expression genes.
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