Sentences with phrase «different types of cancer cells»
Curcumin inhibits the growth and spread of different types of cancer cells, in particular leukemia, hepatic, colorectal, pancreatic, gastric, prostate, breast, and oral cancers.
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A lab - based study showed that myrrh actually inhibited the growth in eight different types of cancer cells.
In a study published this year in Current Drug Targets, a combination of tocotrienols and quercetin induced senescence and promoted apoptosis in many different types of cancer cells, while delaying senescence in healthy cells and rejuvenating formerly healthy senescent cells.
It can also kill many different types of cancer cells by triggering apoptosis (programmed cell death) without affecting normal cells.
Tests on animals and humans alike show that HAMLET kills over 40 different types of cancer cells, all without harming healthy cells.
Interleukin - 8 (IL - 8), a well - known tumor - growth promoting inflammatory cytokine104 is «substantially increased» in a number of different types of cancer cells.105 «We found for the first time that caprylic acid and MCT suppress IL - 8 secretion by Caco - 2 cells [colon cancer cells],» reported Japanese researchers in 2002.106
And, anthocyanins also trigger apoptosis — or cell suicide — in several different types of cancer cells.
Using tumor samples from a patient, they do lab tests to determine which substances can first make the different types of cancer cells uniform and then effectively kill them.
«Different types of cancer cells with different strengths and weaknesses are both present in the tumor at the same time and can work together to spread faster and more efficiently.
As different cancers express different biomarkers, it might be possible to modify the molecular structure of the ruthenium molecule to target different types of cancer cell.»
Not exact matches
Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.
In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.
«Recent studies suggest that epigenetic modifications may contribute to the development of cancer progenitor cells that can induce drug resistance and the relapse of different types of cancer,» said Sibaji Sarkar, PhD, instructor of medicine at BUSM.
The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.
PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.
For each patient, the suitable combination treatment could then be designed, which, in the first step, would turn the variety of different tumor cells into a mass of cancer cells of the same type.
Backman has been studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS) microscopy.
The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.
If the finding that resident memory T cells are the most potent mediators of immunity holds up in different types of cancer, which I think it will, you could take a biopsy of the lung or the pancreas, for example, to see if there are resident T cells there.
They found that the number of copies of lncRNA genes on a chromosome consistently change in 12 different cancer types and lncRNA genes are widely expressed in cancer cells.
«We've seen this in six different types of human cancer cell lines in the lab,» Choudhury said.
• Given the fact that normal cells possess wild - type p53 function, FL118 - induced p53 activation might explain the favorable toxicology profile of FL118: highly toxic to cancer cells but not so in healthy animal cells, and these different consequences might be mediated through p53 activation.
Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.
«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.
They found that silencing the TOR signalling pathway — activated in many different types of cancer — increased ER stress in the cells.
The follow up Biosensors paper, provides a proof - of - principle use of these probes as tools to assess and compare GLUT5 and metabolic activity of different cell types, including normal cells and different cancer subtypes.
Christian Seiser says: «Our results highlight that it is crucial to understand the individual role the various HDAC variants in different cell types and hence different types of cancer, before HDAC inhibitors can be used safely as therapeutics.»
The notable differences in fluorescence intensity observed between normal cells and cancer cells, as well as different cancer types, provide important points of differentiation between different cell types and make these probes promising tools for cancer detection and diagnostics.
If these preclinical studies are successful, the researchers plan to further develop their CAR T cell therapy and test its safety and efficacy for different types of metastatic cancer in upcoming clinical trials.
«Our work outlines the genetic similarities of the tissue and cells in different types of tumors and shows the strong relationships mice can have to other human cancers too.»
They analysed about a million different cell mutations in more than 7,000 tumours from the Cancer Genome Atlas covering 24 types of cCancer Genome Atlas covering 24 types of cancercancer.
By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.
Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
Dr. David Gilley's laboratory at the Indiana University School of Medicine in Indianapolis and Dr. Connie Eaves» laboratory at the BC Cancer Agency's Terry Fox Laboratory in Vancouver, Canada, collaborated to determine how telomeres are regulated in different types of normal breast cells.
The research highlights the importance of investigating different cell types in normal human tissues to understand the cellular origin of cancer and the factors that may contribute to its development.
Hsp90 inhibitors are among several innovative new types of treatment designed to attack cancer indirectly, by destabilising multiple different proteins required for the growth and survival of cancer cells.
A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.
Studying cancer with single - cell technology will allow us to unlock the interactions between different types of cells in tumors — and monitor how these interactions change over time, affecting patients» outcomes.
Expression of Snail represses expression of E-cadherin and induces EMT in different cell types, including breast cancer cells [36, 37].
• Detect Zika virus in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between Zika and dengue • Discriminate different types of bacteria, like E. coli • Detect cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample
Their strategy, described in the Jan. 4, 2009 issue of the journal Nature Medicine, could not only prove a very useful method to faithfully reproduce different types of tumors but also to elucidate the nature of elusive cancer stem cells.
-- discovery awarded international science prize Researcher Allison Cleary has, for the first time, demonstrated that different types of tumor cells cooperate in the development and growth of breast cancer.
While many different types of cancer can occur in the head and neck, squamous cell carcinoma in the most common cancer of the head and neck.
Researcher Allison Cleary has, for the first time, demonstrated that different types of tumor cells cooperate in the development and growth of breast cancer.
Although cancer stem cells have been identified in many different types of cancer, it is becoming increasingly clear that the properties of these cells may vary greatly among the different tumor types.
Many different cell types including fibroblasts, smooth muscle cells, endothelial cells, and cancer cells exert traction forces on the fibrous components of the extracellular matrix.
To develop the methodology, the group analyzed the molecular profiles of human embryonic stem cells and compared them with data for 12,000 samples of 33 different tumor types held by The Cancer Genome Atlas (TCGA), a U.S. public database.
As we have previously suggested, since tumor angiogenesis is very complex and involves a number of different cell types, a multi-target approach for the anti-angiogenic treatment of cancer could be expected to produce better results [18].
Beyond the expansion of the collection of barcoded cell lines for testing larger panels of compounds, next steps will include determining whether PRISM can be used to study the complex interactions between different cell types found within tumors, or to study tumor evolution during cancer development or after cancer treatment.
Similar to primary keratinocytes, long - term — cultured squamous cell carcinoma (30) and many other epithelial cancer cells (30, 31) can also form different types of clones in culture.