Sentences with phrase «disease models center»

The Ospedale San Raffaele Mouse Clinic (OMC) is the follow - up and consolidation of a Regione Lombardia - funded project (EMDM), which aimed at the establishment and implementation of a large, dedicated facility (the European Mouse Disease Models Center) whose goal is the development and functional assessment of mouse disease models, both for the dissection of the underlying pathogenic mechanisms and for the screening and validation of innovative diagnostic and therapeutic procedures.

Not exact matches

«Now we have two interesting models that are selectively targeting specific parts of the brain: the thalamus in FFI and the hippocampus in CJD,» says Jackson, who is now a Group Leader at the German Center for Neurodegenerative Disease.

«Social media data have been suggested as a way to track the spread of a disease in a population, but there is a problem that in an emerging outbreak people also use social media to express concern about the situation,» explains study team leader Sherry Towers of ASU's Simon A. Levin Mathematical, Computational and Modeling Sciences Center.

«This is the first time a compound targeting Gaucher disease has been tested in a mouse model of Parkinson's disease and was shown to be effective,» said the study's senior author, Marie - Francoise Chesselet, the Charles H. Markham Professor of Neurology at UCLA and director of the UCLA Center for the Study of Parkinson's Ddisease has been tested in a mouse model of Parkinson's disease and was shown to be effective,» said the study's senior author, Marie - Francoise Chesselet, the Charles H. Markham Professor of Neurology at UCLA and director of the UCLA Center for the Study of Parkinson's Ddisease and was shown to be effective,» said the study's senior author, Marie - Francoise Chesselet, the Charles H. Markham Professor of Neurology at UCLA and director of the UCLA Center for the Study of Parkinson's DiseaseDisease.

Using CRISPR / Cas9, the Hamon Center team was able to correct the genetic defect in a mouse model of DMD and thus prevent the development of features of the disease, which in boys causes progressive muscle weakness and degeneration, often along with breathing and heart complications.

«This study, carried out using laboratory rats modeling stroke, demonstrated that ischemic stroke — in both its subacute and chronic stages — damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.

Application of sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet - B (UVB) light delayed melanoma onset in a mouse model of the disease, according to data from a team at The Ohio State University Comprehensive Cancer Center Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

«We found many examples in which an entire species should have a serious genetic ailment, but instead were healthy,» said Nicholas Katsanis, Ph.D., director of the Center for Human Disease Modeling and professor cell biology and pediatrics at Duke.

An international research team led by biochemists at The University of Texas Health Science Center at Houston (UTHealth) reduced the sickling of red blood cells in a mouse model of the disease.

Researchers at Rice's Center for Theoretical Biological Physics used computer models to analyze proteins suspected of misfolding and forming plaques in the brains of patients with neurological diseases.

«We think that for the first time, we have a mouse model of anorexia that closely resembles the conditions leading up to the disease in humans,» said study leader Lori Zeltser, PhD, associate professor of pathology & cell biology and a researcher in the Naomi Berrie Diabetes Center.

Dr. Julie Deckers, Prof. Karolien De Bosscher and Prof. Hamida Hammad (all VIB - UGent Center for Inflammation Research) created a mouse model to look further into the relationship between the two diseases.

Using data from the US Centers for Disease Control and Prevention (CDC) Multiple - Cause of Death Files (2006 - 2015), US Census Bureau, US Department of Agriculture Economic Research Service, Agency for Healthcare Research and Quality, and Northeast Regional Center for Rural Development, the study modeled associations between county - level drug - related mortality rates and economic, social, and healthcare environments.

UCLA researchers led by Drs. Peiyee Lee and Richard Gatti at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have used induced pluripotent stem cells (iPSC) to advance disease - in - a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia (A-T).

Modifying our delivery model to include team - based care in concert with patient - centered technologies offers great promise in managing the chronic disease epidemic.»

A new model for post-integration latency in macroglial cells to study HIV - 1 reservoirs of the brain, AIDS, DOI: 10.1097 / QAD.0000000000000691 Link to the original publication As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus and lung diseases.

Congratulations to Umrao Monani, Assistant Professor at the Motor Neuron Center of Columbia University and Cathleen Lutz, Associate Director of Genetic Research Science at The Jackson Laboratory, and their colleagues for their new publication «Postsymptomatic Restoration of SMN Rescues the Disease Phenotype in a Mouse Model of Severe Spinal Muscular Atrophy» in the Journal of -LSB-...]

In 2009, he established the Center for Human Disease Modeling at Duke University, which aims to facilitate collaboration across disciplines and to develop physiologically relevant, scalable tools to study variation among human patient genomes.

The Center, which collaborates with CiRA, is creating human, iPS - based disease models needed to accelerate drug development for a host of devastating for cardiovascular, viral and neurological illnesses.

The construction of the University Technology Center is the next step to enabling Penn State College of Medicine to utilize «big data» to enhance patient care through disease modeling and predictors for disease by more efficiently processing and analyzing clinical information.

Stomnes, a postdoctoral researcher working with Philip Greenberg, M.D., and Sunil Hingorani, M.D., Ph.D., at the Fred Hutchinson Cancer Center at the University of Washington, has developed a mouse model of pancreatic ductal adenocarcinoma that is particularly good for studying this disease.

«We found that having elevated levels of IL - 15 in the gut could initiate all the early stages of celiac disease in those who were genetically susceptible, and that blocking IL - 15 could prevent the disease in our mouse model,» said Bana Jabri, MD, PhD, associate professor of medicine and pathology, co-director of the Digestive Disease Research Core Center and a member of the Celiac Disease Center and Comprehensive Cancer Center at the University of Cdisease in those who were genetically susceptible, and that blocking IL - 15 could prevent the disease in our mouse model,» said Bana Jabri, MD, PhD, associate professor of medicine and pathology, co-director of the Digestive Disease Research Core Center and a member of the Celiac Disease Center and Comprehensive Cancer Center at the University of Cdisease in our mouse model,» said Bana Jabri, MD, PhD, associate professor of medicine and pathology, co-director of the Digestive Disease Research Core Center and a member of the Celiac Disease Center and Comprehensive Cancer Center at the University of CDisease Research Core Center and a member of the Celiac Disease Center and Comprehensive Cancer Center at the University of CDisease Center and Comprehensive Cancer Center at the University of Chicago.

NYSCF partners with a broad range of institutions, foundations, centers and companies in a variety of ways ranging from the creation of fundamental research resources such as iPSC lines for a disease area to developing human disease models in vitro to enable drug discovery and toxicity testing.

For this study, Jabri and colleagues combined insights and data from celiac disease patients who had been cared for at the University of Chicago's Celiac Disease Center with experiments using a mouse model of the disease developed in hdisease patients who had been cared for at the University of Chicago's Celiac Disease Center with experiments using a mouse model of the disease developed in hDisease Center with experiments using a mouse model of the disease developed in hdisease developed in her lab.

Vessels and vanishing bones: Development and characterization of a mouse model of Gorham - Stout disease Michael Dellinger, University of Texas Southwestern Medical Center

The Center for Predictive Medicine recognizes the challenges of translational research such as in designing and implementing high - throughput screens and assessing small molecules and potential vaccines for their efficacy in small animal models of disease.

The Jackson Laboratory's Rare and Orphan Disease Center in Bar Harbor is creating mouse models with Talia's very rare genetic disorder in the hopes that scientists can use the mice to find a treatment for the disorder.

The center will develop techniques to test the drugs in cell culture and animal models, to validate their effects on a certain disease.

Requests for Single Reprints: Martial L. Ndeffo - Mbah, PhD, Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, 135 College Street, Suite 200, New Haven, CT 06510; e-mail, [email protected].

Current Author Addresses: Drs. Ndeffo - Mbah and Galvani and Ms. Parpia: Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, 135 College Street, Suite 200, New Haven, CT 06510.

Disease modeling shows that treatment centers, safe burials are containing outbreak in Liberia

Using a mouse model for this disease, which in humans involves the destruction of white matter in the brain, a research team led by Albee Messing, director of the UW — Madison Waisman Center, found that a protein behind the symptoms of the disease, called GFAP, is broken down more rapidly in the body than researchers previously found in cell culture studies.

At JAX's new Alzheimer's Disease Precision Models Center, Howell is genetically manipulating mice to understand how unhealthy lifestyle habits trigger immune responses in the brain, leading to a cascade of events that may ultimately impair thinking and memory, as in Alzheimer's dDisease Precision Models Center, Howell is genetically manipulating mice to understand how unhealthy lifestyle habits trigger immune responses in the brain, leading to a cascade of events that may ultimately impair thinking and memory, as in Alzheimer's diseasedisease.

Naturopathic medicine is a patient - centered model of care that blends the best of modern science and traditional healing wisdom to develop comprehensive treatment plans that not only treat disease but also allow patients to restore optimal health.

The Functional Medicine model is an individualized, patient - centered, science - based approach that empowers patients and practitioners to work together to address the underlying causes of disease and promote optimal wellness.

Examples of studies conducted with assistance of the Center are pre-clinical studies of orthopedic devices intended for animal and human use, clinical studies of treatment and prevention of respiratory diseases in horses and animal clinical trials evaluating the treatment of bladder cancer in Scottish Terriers, an animal model of human bladder cancer.

Regarding climate change effects in the WHO results, according to the UK's Hadley Center climate model (HadCM2 — IS92a scenario) climate - change induced disease risks could double by the year 2030 — all other factors held constant.

C40 Cities Climate Leadership Group, 12 California, 7, 68, 102, 128, 169 - 170, 187, 196, 232 - 234, 245 California Energy Commission, 232 Cambridge Media Environment Programme (CMEP), 167 - 168 Cambridge University, 102 Cameron, David, 11, 24, 218 Cameroon, 25 Campbell, Philip, 165 Canada, 22, 32, 64, 111, 115, 130, 134, 137, 156 - 157, 166, 169, 177, 211, 222, 224 - 226, 230, 236, 243 Canadian Meteorological and Oceanographic Society (CMOS), 15 Cap - and - trade, 20, 28, 40 - 41, 44, 170, 175 allowances (permits), 41 - 42, 176, 243 Capitalism, 34 - 35, 45 Capps, Lois, 135 Car (see vehicle) Carbon, 98, 130 Carbon Capture and Storage (CCS), 192 Carbon Capture and Storage Association, 164 Carbon credits (offsets), 28 - 29, 42 - 43, 45 Carbon Cycle, 80 - 82 Carbon dioxide (CO2), 9, 18, 23, 49 - 51, 53, 55, 66 - 67, 72 - 89, 91, 98 - 99, 110, 112, 115, 118, 128 - 132, 137, 139, 141 - 144, 152, 240 emissions, 12, 18 - 25, 28 - 30, 32 - 33, 36 - 38, 41 - 44, 47, 49, 53, 55, 71 - 72, 74, 77 - 78, 81 - 82, 108 - 109, 115, 132, 139, 169, 186, 199 - 201, 203 - 204, 209 - 211, 214, 217, 219, 224, 230 - 231, 238, 241, 243 - 244 Carbon Dioxide Analysis Center, 19 Carbon Expo, 42 Carbon, footprint, 3, 13, 29, 35, 41, 45, 110, 132 tax, 20, 44, 170 trading, 13, 20, 40, 43, 44, 176, 182 Carbon monoxide (CO), 120 Carbon Reduction Commitment (CRC), 44 Carlin, George, 17 Carter, Bob, 63 Carter, Jimmy, 186, 188 Cato Institute, 179 CBS, 141, 146 Center for Disease Control, 174 Center for the Study of Carbon Dioxide and Global Change, 62, 139 Centre for Policy Studies, 219 CERN (European Organization for Nuclear Research), 96 Chavez, Hugo, 34 Chicago Tribune, 146 China, 29, 32 - 33, 60 - 62, 120, 169, 176, 187 - 188, 211, 216, 225 - 226, 242 - 243 China's National Population and Planning Commission, 33 Chinese Academy of Sciences, 60 Chirac, Jacques, 36 Chlorofluorocarbons, 42 - 43, 50 Choi, Yong - Sang, 88 Christy, John, 105 Churchill, Winston, 214, 220 Chu, Steven, 187 Citibank (Citigroup), 40, 176 Clean Air Act, 85, 128 - 129 Clean Development Mechanism, 42 Climate Action Partnership, 14 Climate alarm, 4, 13, 21, 32, 35, 38, 56, 102 - 103, 115 - 117, 120, 137, 156, 168, 173, 182 Climate Audit, 66 Climate change, adaptation, 39, 110, 112 mitigation, 16, 39, 110 Climate Change and the Failure of Democracy, 34 Climate Change: Picturing the Science, 121 Climate Change Reconsidered, 242 Climate conference, 38 Cancun, 18, 29, 36 - 37, 124 - 125, 242 Copenhagen, 33, 36, 109, 125, 156, 158, 175, 241 - 242 Durban, 13, 36 - 37, 166, 242 - 243 Climategate, 2, 67, 152, 158 - 170, 180, 182, 242 Climate Protection Agreement, 12 Climate Research Unit (CRU), 48, 67, 120, 147, 152 - 153, 158 - 160, 162 - 163, 165 - 167, 169 Climate Science Register, 142 Climatism, definition, 2, 7 Clinton, Bill, 176, 178 Clinton Global Initiative, 176 CLOUD project, 96 Club of Rome, 21, 186 CO2Science, 59, 61 - 62, 66, 131 Coal, 19 - 20, 39 - 41, 80, 126, 128 - 129, 175, 185 - 186, 188 - 190, 192 - 196, 199 - 201, 209, 214, 217, 219, 222, 229 Coase, Ronald, 145 Coca - Cola, 138 Cogley, Graham, 156 Cohen, David, 220 Colorado State University, 117, 181 Columbia University, 7 Columbus, Christopher, 58 Computer models, 16, 51 - 53, 56, 67, 72, 74,77 - 79, 82, 87, 89 - 91, 94, 105, 110 - 111, 120, 124, 138 - 140, 168, 171,173, 181, 238, 240, 246 Conference on the Changing Atmosphere, 15 Consensus, scientific, 12 Copenhagen Business School, 134 Coral, 53 Corporate Average Fuel Economy, 22 - 23 Cosmic Rays, 72, 93 - 99, 180 Credit Suisse, 176 Crow, Cheryl, 30 Crowley, Tom, 167 Cuadrilla Resources, 224 - 225 Curry, Judith, 164, 167 Cycles, natural, 3, 16, 57, 62 - 63, 66 - 69, 72, 80, 99, 103, 138, 238, 240 Milankovich, 62, 67, 80 Cyprus, 134 Czech Republic, 12, 37

Topics: Chronic Disease Community Needs Assessment Cultural Competence EBP Implementation Home Visiting Intimate Partner Violence Life Course Model Patient - centered Medical Home

Public Health Leadership Initiative National Center for Injury Prevention and Control, Centers for Disease Control and Prevention Describes a 3 - year project to identify best practice models of State public health leadership in preventing child maltreatment and promoting safe, stable, and nurturing relationships for children.

Schools, mental health centers, IDD organizations and other systems implementing positive behavior support at a systems level use a multi-tiered prevention model that was borrowed from a public health model for disease prevention.