Drug companies find themselves unable to reproduce promising drug targets published by the best academic institutions.
Not exact matches
Says Bapty: «If a CRO is nimble and can evolve technology that can enable its clients to get a
drug approved faster or to reduce the risk of a clinical study, or even save them development money in the long run, that
company will
find it has a long - term business plan.»
That research will be crucial: An earlier effort by another
company, Pathway Genomics, to create a «liquid biopsy» for cancer was greeted in September by a stern letter from the Food and
Drug Administration (FDA) warning that the agency had «not
found any published evidence that this test or any similar test has been clinically validated as a screening tool for early detection of cancer in high risk individuals.»
In outcome - based pricing,
drug companies will know that payment is coming if the treatment works, and that means more incentive to develop new cures and to
find new applications for existing
drugs.
Merck is the latest
company to weather bad news in the Alzheimer's
drug race, halting a late - stage trial yesterday in an experimental amyloid - targeting candidate called verubecestat after a data monitoring committee said there was «virtually no chance of
finding a positive clinical effect,» Reuters reported.
The Belgian group specialises in the research of novel
drugs based on nano - bodies
found in the immune systems of llamas and alpacas, for which it partners with several of the world's largest pharmaceutical
companies.
Microsoft and Stanford researchers have
found Web searches can help the FDA and
drug companies uncover dangerous
drug interactions.
Formerly a Food and
Drug Administration regulator, he's now an educator, TV host, and senior scientist at Memphis Meats, the
company that Valeti
founded in 2016 and whose laboratory he is showing me.
And Valeant's round - about method of funding research, if that's what it's actually doing, seems a lot less cost effective, with all of the bankers and lawyers and hedge fund managers taking chunks of deals than if
drug companies directly devoted a portion of their sales toward
finding new
drugs.
One of the great
findings of this study is that you can be in a great
company and be doing it in steel, in
drug stores, or in grocery stores.
As big pharmaceutical
companies find that the patents for some of their blockbuster
drugs are expiring, they are desperately reaching out to replenish their
drug pipelines.
Shares of PTC Therapeutics, Inc. (NASDAQ: PTCT) gained more than 13 percent Friday after the FDA
found that the
company's experimental
drug to treat Duchenne muscular dystrophy may work.
The HHS secretary went on to say that his agency wanted to
find ways for Medicaid and Medicare to bring
drug prices down by creating more resources to negotiate with pharma
companies.
A 2017 investigation into lobbying efforts by «Big Pharma» conducted by The Washington Post and 60 Minutes
found that the
companies spent more than $ 106 million to lobby Congress in an effort to pass more favorable
drug laws.
Her personal physician likewise declined to provide the lethal
drug, yet her managed - care insurance
company found her a doctor who did provide it.
Clearly, waiting three years to tell her audience, she was obviously shopping around the
drug companies to
find the biggest deal she could wrangle as a paid spokesperson.
The health professional who is supportive of breastfeeding will make efforts to
find out how to avoid interruption of breastfeeding (the information in white pages of the blue Compendium of Pharmaceutical Specialties and the PDR are not a good references — every
drug is contraindicated according to them as the
drug companies are more interested in their liability than in the interests of mothers and babies).
The health professional who is supportive of breastfeeding will make efforts to
find out how to avoid interruption of breastfeeding (the information in white pages of the blue Compendium of Pharmaceutical Specialties is not a good reference — every
drug is contraindicated according to it as the
drug companies are more interested in their liability than in the interests of mothers and babies).
«If a multinational
company developed a product that was a nutritionally balanced and delicious food, a wonder
drug that both prevented and treated disease, cost almost nothing to produce, and could be delivered in quantities controlled by consumers» needs, the announcement of this
find would send its shares rocketing to the top of the stock market.
Today, for instance, I can only
find five ad campaigns running: one for
drug company Novartus, one for a prescription benefit plan (also running in the Post's political section), a CATO Institute ad for a book, an ad from the American Council of Life Insurers and an Environmental Defense ad on global warming.
The so - called «Pharma Bro,» notorious for raising the price of a potentially life - saving
drug by 5,000 percent, was
found guilty today of defrauding investors in two hedge funds and in Retrophin Inc., a pharmaceutical
company he co-founded.
Many of our Olympic boxing heroes will tell how it was their local club and its coaches that saved them from a life of gangs, crime, and
drugs, and clubs from Fitzroy Lodge in London to the National Smelting
Company Boxing Club in my constituency are full of young men and women who have
found their salvation in boxing.
It also should be pointed out the profit motive of
drug companies is a major reason why they haven't worked on
finding ways to prevent the spread of infectious diseases such as Ebola.
He has helped
found at least two dozen biotech
companies, with foci ranging from cancer
drug delivery to products for hair and skin.
He added that many
drug companies have stopped their research into
finding new medicines for epilepsy.
PreScience Labs, a U.S.
company founded by Geschwind, received approval for a phase I study from the U.S. Food and
Drug Administration in 2013.
The study
findings have already led to a collaboration with a pharmaceutical
company to test
drugs targeting that pathway, he said.
Opsona Therapeutics, for example, a
drug development
company focusing on the regulation of the human immune system, was
founded in Dublin in 2004 by three immunologists at Trinity College Dublin.
For women, a
drug that works between the ears is better than one that functions between the legs, a German pharmaceutical
company has
found.
With a weakened global economy and dwindling
drug pipelines, many of the
companies that made the list of Science's 2009 top employers are
finding that maintaining innovation through collaborations and partnerships is critical to success.
Karikó and Weissman
founded a
company hoping to develop
drugs from the discovery, and won nearly a million dollars in small business grants from the U.S. government for animal studies.
Henry Nicholls sets out to uncover the truth about his condition, only to
find that
drug companies are more interested in inducing narcolepsy than curing it
A 2003 survey, led by Scott Kim, an associate professor in the bioethics program at the University of Michigan at Ann Arbor, showed that if participants were told that a researcher or institution testing a treatment was being funded by the pharmaceutical
company that made the
drug, 40 percent would be more willing to participate — a
finding Kim chalks up to an appreciation for up - front honesty.
THE Wrigley
Company of Chicago believes it has
found a way round the US government's ban on adding caffeine to chewing gum or sweets without the products being classified as
drugs.
«These
findings could allow the pharma
companies to open up large libraries of potent
drug candidates earlier discarded due to solubility problems and try them again together with Upsalite,» says Maria Strømme, Professor at the Division of Nanotechnology and Functional Materials at Uppsala University.
A U.S. biotechnology
company has
found early success with a cancer
drug developed by a supercomputer, BBC reports.
Six are still being investigated, but so far, NIH has
found just one case in which rules were broken: that of a psychiatrist at Emory University in Atlanta who allegedly failed to report payments he received from
drug and device
companies.
For decades, pharmaceutical
companies have treated ß amyloid as a «freak» with no beneficial purpose, and focused nearly all their energies on
finding drugs to eliminate the molecules, he says.
In response to the hostility they faced as a result of their mixed marriage, Larry and Anne expatriated to Mexico City where Larry
found employment with Syntex, the
company that had recently introduced the first synthetic birth control
drugs.
Hoping to cash in on personalized cancer therapy, a new
company called Foundation Medicine —
founded in part by genome guru Eric Lander of the Broad Institute — plans to develop tests for genetic glitches in tumors that make them vulnerable to specific
drugs, reports the United Kingdom's Times Online.
A team of researchers
found that D.C. - based health care providers who got gifts — including cash, meals and ownership interests — from pharmaceutical
companies prescribed more
drugs per patient, wrote more expensive prescriptions and were more likely to recommend brand names.
ProPublica collected the
drug company's publications — which were hard to
find and even harder to extract data from — and put them in an easy - to - search database.
Harris cited other examples of concern — a review of 100 studies in the field of psychology in which the
findings in only about a third of the studies were reproducible; an effort by scientists at Bayer, another large
drug company, that managed to reproduce the
findings of only one - quarter of the studies under review; a just - published review of 25 historical candidate genes for schizophrenia which
found no evidence that the candidate genes are more associated with the disease than other genes.
If a pharmaceuticals
company — which might
find 10 per cent of the undiscovered
drugs — paid out all its profit to the owners, this would amount to only $ 1.32 a hectare.
So, if a pharmaceutical
company creates an Alzheimer's
drug to target memory based on research into one type of memory — the part of the brain responsible for
finding missing objects, for example — but doesn't also have data on the type of memory that helps individuals remember the important people, places and things in their life, it runs the risk of producing a product that helps a person remember where they put the car keys, but not how they met their spouse.
The great demand for such new substances in the field of
drug development suggested that this might be our chance to
found a biotech
company.
The report
found that the US Food and
Drug Administration has not clearly communicated to drug companies the need to include women in numbers proportionate to the numbers of women in the population who might bene
Drug Administration has not clearly communicated to
drug companies the need to include women in numbers proportionate to the numbers of women in the population who might bene
drug companies the need to include women in numbers proportionate to the numbers of women in the population who might benefit.
The National Institutes of Health (NIH) today unveiled the details of its $ 20 million program for
finding new uses for abandoned
drugs — along with five more participating
companies.
The researchers, including scientists from pharmaceutical
company AstraZeneca, report in an advanced online publication in Nature Medicine on May 4, that their
findings indicate «an underappreciated genomic heterogeneity» in mechanisms of resistance to tyrosine kinase inhibitor (TKI)
drugs that target the Epidermal Growth Factor Receptor (EGFR) mutation that drive some cases of non-small cell lung cancer (NSCLC).
[1] The guidelines call on the Food and
Drug Administration to clarify what information pharmaceutical
companies can share with stakeholders beyond the information now
found on FDA labels.