Sentences with phrase «during synaptic vesicle»
During synaptic vesicle fusion, the soluble N - ethylmaleimide - sensitive factor — attachment protein receptor (SNARE) protein syntaxin - 1 exhibits two conformations that both bind to Munc18 - 1: a «closed» conformation outside the SNARE complex and an «open» conformation in the SNARE complex.
http://science.sciencemag.org/ Not exact matches
The synaptic vesicle protein that mediates membrane fusion during exocytosis also regulates the rate and extent of this process by controlling vesicle tethering.
During this time, we together with our long - time collaborators Reinhard Jahn and Jose Rizo, and in parallel with Richard Scheller and others, discovered the role of SNARE and SM proteins in synaptic vesicle fusion.
During an action potential, calcium influx into the presynaptic terminal triggers the fusion of synaptic vesicles with the plasma membrane, leading to the release of transmitter through the process of exocytosis.