Adjusted for post-conceptual age on
the EEG visit day, regression analysis did not reveal an association of prenatal or postnatal EPDS with the bilateral frontal activity and its asymmetry in 6 - month and 18 - month - old infants (Table 2).
Briefly, in the female sample, greater - postnatal - than - prenatal maternal depressive symptoms were significantly associated with greater right frontal activity (β = -0.262, p = 0.020, df = 72) and greater relative right frontal asymmetry in infants at 6 months of age (β = -0.426, p < 0.001, df = 72) after adjusting for post-conceptual age on
the EEG visit day.
Severity of maternal depressive symptoms was not associated with bilateral functional connectivity and its asymmetry in 6 - month and 18 - month - old infants, after adjusting for post-conceptual age on
the EEG visit day (Table 2).
Neither prenatal nor postnatal EPDS scores independently associated with bilateral functional connectivity and its asymmetry in 6 - month and 18 - month - old infants, after adjusting for post-conceptual age on
the EEG visit day (Table 2).
After adjusting for post-conceptual age on
the EEG visit day, greater - postnatal - than - prenatal maternal depressive symptoms were significantly associated with greater right frontal activity (Table 2, Fig 2b) and greater relative right frontal asymmetry in infants at 6 months of age (Table 2, Fig 2c).
After adjusting for post-conceptual age on
the EEG visit day and birth weight, neither the 6 - month frontal activity nor frontal FC predicted CBCL externalizing and internalizing scores of infants at 24 months of age (Table 3).
Subsequently increasing maternal depressive symptoms from the prenatal to postnatal period predicted lower right frontal connectivity within 18 - month infants but not among 6 - month infants after controlling for post-conceptual age on
the EEG visit day.
However, increasing maternal depressive symptoms from the prenatal to postnatal period predicted greater right frontal activity and relative right frontal asymmetry amongst 6 - month infants but these finding were not observed amongst 18 - month infants after adjusted for post-conceptual age on
the EEG visit day.
Moreover, greater - postnatal - than - prenatal maternal depressive symptoms were associated with lower right frontal FC in 18 month olds (β = -0.382, p = 0.002, df = 58), after adjusting for post-conceptual age on
the EEG visit day.
Not exact matches
Post-conceptual age on the
visit day of
EEG was entered as covariate for the
EEG measures.
First, we examined the relationships of plausible covariates, including gender, birth - weight, post-conceptual age on the
visit day (gestational age +
days of life since birth to the
visit day), ethnicity, prenatal smoking exposure, and child sleep condition at the time of
EEG recording with outcome measures (frontal
EEG power, functional connectivity at 6 and 18 months of age, or behavioral scores at 24 months of age).