Sentences with phrase «er stress conditions»

In the study, Chih - Chi Andrew Hu, Ph.D., associate professor in Wistar's Immunology, Microenvironment & Metastasis Program, and colleagues characterized a novel phosphorylation that regulates the function of IRE1 in response to specific ER stress conditions.

Not exact matches

An over-burdened — or «stressed» — ER can result in proteins becoming disorganized, a condition which cells seek to rectify by undertaking «unfolded protein response», or UPR.

It turns out that neuropathic pain is triggered when the body experiences endoplasmic reticulum (ER) stress, a condition in which the production and transport of protein exceeds the cells» capacities, say researchers from the University of California, Davis.

A medication that blocks ER stress is already on the market to treat an entirely different condition called urea cycle disorder.

Findings in this heavily litigated area are often predicated on erroneous clinical assumptions such as: that doctors accept uncritically and at face value what the client says about their history (HE (DRC — credibility and psychiatric reports) Democratic Republic of Congo [2004] UKIAT 00321); that only psychiatrists can diagnose conditions such as post-traumatic stress disorder (HH (Ethiopia) v SSHD [2007] EWCA Civ 306, [2007] All ER (D) 259 (Mar)-RRB-; and that doctors do not consider alternative explanations, including fabrication when, in fact, this is integrated into medical training and has always been a specified requirement of the IP (para 105 (f)-RRB-.