Sentences with phrase «es cell researcher»

This may still be speculative — Sherry agrees that it's not as though Sherley's grant was denied because it went directly to an ES cell researcher.

Not exact matches

Human ES cells had just been isolated for the first time, and researchers were excited about their potential use in regenerative medicine.

The researchers succeeded in changing the DNA of the E coli bacteria in such a way that the substance CB [8](a small molecule of two nanometres in size with a namederived from the resemblance of this molecule with a pumpkin of the family of Cucurbitaceae) attaches to a protein on the cell membrane.

And it suggests that stem cells derived from embryos should remain the primary reference for iPS cells when researchers want to compare how cells from diseased patients behave, says Nissim Benvenisty of Hebrew University of Jerusalem, who has studied differences between ES cells and iPS cells derived from carriers of fragile X syndrome.

In a paper published online yesterday in Stem Cells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embCells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells — from one of the 13 late - arrested embryos.

Lanza says researchers could use the technique to derive ES cells from embryos undergoing PGD.

To fend off HIV, researchers introduced one vaccine (ALVAC - HIV) to induce a T cell response — thereby alerting the immune system — and another (AIDSVAX B / E) later to spur an antibody response.

Some researchers have questioned whether iPS cells measure up to ES cells.

The embryo used to derive an ES cell is not genetically identical to the donor of the cell that is transformed into an iPS cell, so researchers expect some discrepancies in gene activity.

Indeed, one of the first things researchers tried to make from ES cells was pancreatic β cells.

The fact that the researchers made their iPS cells from cells that matured in the lab from ES cells, instead of from the cells of a patient or donor, means that they still might carry traces of the ES cells» gene activity patterns.

When the researchers measured gene activity, they found that the iPS cells were more similar to the ES cells they descended from than to each other, suggesting that the source of the cells explains many of the disparities researchers had noted between the two stem cell types.

If the cells can be fertilized and develop into viable embryos, and if human ES cells turn out to have similar powers, such cells could allow researchers to get around some of the expense and ethical questions that arise from using donated eggs for therapeutic cloning experiments.

A few months ago, researchers reported that oocytes can form spontaneously in colonies of mouse ES cells (ScienceNOW, 1 May), the first demonstration that ES cells can form germ cells in vitro.

Using cutting edge «disease in a dish» technologies, the researchers are now following up the leads discovered in blood cell lines in neurons induced from stem cells derived from the blood of PMDD patients — in hopes of gaining a more direct window into the ESC / E (Z) complex's role in the brain.

An international team led by researchers at Johns Hopkins University in Baltimore, Maryland, compared early - passage and late - passage versions of nine human ES cells lines obtained from labs around the world.

In the meantime, both Xu and Daley say the results underscore the need to continue work with ES cells so that researchers can fully understand — and try to overcome — the differences.

Researchers at Kumamoto University added VEGF to undifferentiated ES cells and tracked the behavior of the entire genome and epigenome changes over time in vitro.

To their surprise, many of the cells failed to form teratomas at all — similar to what the researchers saw when they transplanted ES cells from one mouse strain to another.

The difference visualized by the researchers is in a region of the E glycoprotein that flaviviruses may use to attach to some human cells.

In order to determine that the transformations work properly and the cells are safe for therapeutic use, researchers need to compare the iPS cells to ES cells, which means destroying embryos.

Now researchers led by the Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute have managed to induce a ground state by rewiring the genetic circuitry in human embryonic stem (ES) cells and in adult cells that have been induced into a pluripotent state.

When researchers express interest in obtaining a certain knockout mouse line, the repositories will send them live mice, frozen embryos, sperm, and / or ES cells, so they can study the mice in their own labs.

She joined Dr. Rik Derynck's lab at the University of California San Francisco, as a postdoctoral researcher to explore the mechanisms of TGF - b signaling for the maintenance of human ES / iPS cell pluripotency.

«This discovery will advance our understanding of stem cell epigenetics and chromatin structures, provide potential mechanisms on maintaining the hallmark properties of ES cells, and help researchers with the rich source of information to better understand some of the unique features — such as self - renewal and pluripotency — of human embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.

Researchers marked these newly minted cells, which they called ES - TS cells, and injected them into mouse embryos.

Researchers performed ES cell cultures, RNA preparations and validated microarray data: IA KA NB PYB MXD MG EK SL MR AR MPS MT. Results were discussed among all Consortium partners.

Closely monitoring several markers of cell damage (including creatine kinase, lactate dehydrogenase, prostaglandin - E and tumor necrosis factor - alpha) in their sample of 18 male athletes (who used 20 grams of creatine monohydrate per day for five days, mixed with 60 grams of maltodextrine), the researchers found levels of these markers were reduced after the race, compared to 16 control subjects who took only the maltodextrine.

For those suffering from lead or other heavy metal poisoning, a protective diet that avoids processed foods and emphasizes the central components of a nutrient - dense and antioxidant - rich WAPF - style diet is essential (see sidebar).21 Nutritional status shapes susceptibility to lead toxicity in important ways, affecting lead's intestinal absorption; its mobilization, distribution and retention in the body; and excretion.22 Because oxidative stress is a likely mechanism explaining some of lead's toxic actions, some investigators have begun to explore whether natural antioxidants and trace minerals may help mitigate lead - induced cell damage.17 Specifically, researchers in Spain found that administration of vitamins A, B6, C and E along with zinc modulated some of the negative effects of lead exposure in rat pups, confirming the influence of nutritional factors on health outcomes following lead exposure.17 Vitamin D also should be a major component of a protective diet.