Not exact matches
- Intense
stress early in
life can alter the brain's neurotransmitter systems and cause
changes in the brain similar to those seen in adults with depression.
Persistent
changes in corticotrophin - releasing factor systems due to
early life stress: Relationship to the pathophysiology of major depression ad post-traumatic
stress disorder.
Scores of animal and human studies show that
early life stress, such as severe
early social deprivation, leads to long - term
changes in the brain, cognitive and social problems, and heightened susceptibility to anxiety, depression, and drug abuse in adulthood.
That might strengthen the evidence from the current study that the
changes arise solely from the physical fact of pregnancy and not, for instance, from the
stress and sleep deprivation that all parents experience
early in an infant's
life.
Mouse studies have shown that
stress, particularly
early in
life, can
change microbial communities, and not in a good way.
A few interesting articles in
early life human microbiome, plus: A comparison between Staphylococcus epidermidis commensal and pathogenic lineages from the skin of healthy individuals
living in North American and India; A new tool to reconstruct microbial genome - scale metabolic models (GSMMs) from their genome sequence; The seasonal
changes in Amazon rainforest soil microbiome are associated with
changes in the canopy; A specific class of chemicals secreted by birds modulates their feather microbiome; chronic
stress alters gut microbiota and triggers a specific immune response in a mouse model of colitis; and evidence that the short chain fatty acids profile in the gut reflects the impact of dietary fibre on the microbiome using the PolyFermS continuous intestinal fermentation model.
By identifying the
stress syndrome
early enough and taking measures (like saying NO to people or
changing jobs or careers) you may be well and truly saving your
life.
I just published an article along the same lines of risk mitigation, advocating for a specific financial cushion to bullet - proof (as well as one can)
early retirement plans and ease the
stress of such a big
life change.
* Cats that were weaned too
early, are bored, left alone for long periods of time, or overly
stressed by
changes in their normal routines or
living situations, often react to their anxieties by engaging in excessive licking.
Ending the air pollution that causes
early death and makes the
lives of millions much more difficult will also tackle the emissions that lead to climate
change, the Institute
stresses.
Selina Ward studies the
early life history stages of corals and the responses of reproduction and recruitment to environmental
stresses such as temperature
change, ocean acidification, elevated nutrients and Trichodesmium.
Over the past ten years, at least 27 studies in humans, and many in other animals, have identified one candidate gene in particular, known as NR3C1, which appears to be linked to methylation - induced
changes in response to
early life adversity and parental
stress.
Preclinical studies suggest that
stress early in
life can promote long - term
changes in multiple neurochemical systems (6, 7).
In humans, both the HPA system and the autonomic nervous system show developmental
changes in infancy, with the HPA axis becoming organized between 2 and 6 months of age and the autonomic nervous system demonstrating relative stability by 6 to 12 months of age.63 The HPA axis in particular has been shown to be highly responsive to child - caregiver interactions, with sensitive caregiving programming the HPA axis to become an effective physiological regulator of
stress and insensitive caregiving promoting hyperreactive or hyporeactive HPA systems.17 Several animal models as well as human studies also support the connection between caregiver experiences in
early postnatal
life and alterations of autonomic nervous system balance.63 - 65 Furthermore, children who have a history of sensitive caregiving are more likely to demonstrate optimal affective and behavioral strategies for coping with
stress.66, 67 Therefore, children with histories of supportive, sensitive caregiving in
early development may be better able to self - regulate their physiological, affective, and behavioral responses to environmental stressors and, consequently, less likely to manifest disturbed HPA and autonomic reactivity that put them at risk for
stress - related illnesses such as asthma.
So many relationships break up in the very
early years of a child's
life when there's so much
stress on families, and the whole world
changes for relationships.
The Americans»
Changing Lives Study which involved 3617 participants found that higher levels of parental
stress were related to poorer self - rated health in parents.2 Moreover, parental
stress is a known risk factor for child maltreatment and family violence, both of which are increasing globally.3 These
early adverse events are detrimental to children's health and development.
When parenting challenges specific to parenting an
early adolescent (e.g., the need to cope with increased youth argumentativeness and moodiness) are added to the
stress parents experience in other domains of
life (Silverberg 1996), learning new discipline practices may be insufficient to promote adaptive coping with the
changing parent — adolescent relationship.