Sentences with phrase «eliminating genes in mice»

Eliminating genes in mice is a standard technique for determining their function; the resultant animals are called knockout mice.

Not exact matches

Their report, published May 10 in the journal Nature Communications, suggests that among more than a dozen different lines of mice developed around the world to mirror autism caused by mutations to the SHANK3 gene, Duke researchers are the first to create a mouse in which that gene has been completely eliminated.

The researchers used mice in which the telomerase gene was eliminated; specifically in bone marrow cells.

But researchers will have to figure out how to eliminate the viral DNA used to introduce the genes, which in Yamanaka's experiments led to cancers in 20 percent of mice grown from blastocysts.

Mitchell and her colleagues eliminated this possibility when they deleted these nearby regions in the genome of mice and found there was no impact on the gene's ability to be turned on in embryonic stem cells.

After conducting studies in both humans and mice, the researchers said this new schizophrenia risk gene, called C4, appears to be involved in eliminating the connections between neurons — a process called «synaptic pruning,» which, in humans, happens naturally in the teen years.

They previously showed that knocking out (eliminating) the gene Tff1 in mice induces gastric lesions that include low - and high - grade dysplasia and adenocarcinomas.

The researchers also reported that eliminating one of those genes, Rab27, led to regeneration of axons in the optic nerve or spinal cord of mice.