Quantitative analysis of
endocytosis with cytoplasmic pHluorin chimeras.
Dr. Taraska's lab studies the structural cell biology of exocytosis and
endocytosis with advanced imaging methods including live cell microscopy, superresolution fluorescence, and electron microscopy.
She still runs an eight - person lab, studying
endocytosis with four grad students who probably don't have to attend as many lab meetings as they used to.
Not exact matches
After secretion, apolipoprotein E and cholesterol associate
with high - density lipoprotein to form a particle that can deliver cholesterol to the liver by receptor - mediated
endocytosis.
While working on his Ph.D., Dr. Taraska investigated the processes of triggered exocytosis and
endocytosis in neuroendocrine cells
with high - resolution microscopy methods.
With this new version they used blue light to trigger
endocytosis.
Moreover, examination of the role of Mcf1 can be dissected genetically using mutants that either interfere
with its
endocytosis into target cells, or Rac signalling mutants that hint at early and unexpected Mcf1 mediated effects on the phagocyte cytoskeleton.
We know the initial target and the mechanism... [But] in order to step into [the treatment] stage, we should probably work a little bit more to know by what mechanism the microtubules interfere
with endocytosis.»
Methods: Researchers Harish Shankaran, Haluk Resat and Wiley paired a new module - based systems theory approach
with quantitative metrics for network function to show that receptor / ligand properties such as
endocytosis can be described by just a few control parameters.
We have been studying
endocytosis in a broader, systems perspective, by combining quantitative imaging, genome - wide RNAi screens
with systems biology analysis.
«Without this specialized neurotransmitter recycling and
endocytosis, synaptic vesicles are not recycled fast enough to keep up
with nerve and muscle cell activity,» she said.
All cells were targeted
with conjugates of gold nanoparticles (NPs) through an antibody - receptor -
endocytosis - nanocluster mechanism that produced NP clusters.
Coated pits, associated
with endocytosis, were also present on iPS - RPE cells (Fig. 2E).
This rather simplistic view is now changing
with emerging evidence that
endocytosis is an integral component of the cell signalling machinery, regulating aspects such as the duration, intensity, integration and spatial distribution of signals.
✓ Neurotoxicity: WGA can cross your blood - brain barrier33 through a process called «adsorptive
endocytosis,» pulling other substances
with it.
✓ Neurotoxicity — WGA can cross your blood - brain barrier through a process called «adsorptive
endocytosis,» pulling other substances
with it.