Sentences with phrase «epigenetic modifications do»
Epigenetic modifications do not affect the DNA sequence of genes, but change how the DNA is packaged and how genes are expressed.
https://www.sciencedaily.com/
These epigenetic modifications do not change the genetic code, but may contribute to the inhibition of gene expression, causing the cells to produce smaller amounts of the corresponding proteins.
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By contrast, in more than 90 % of endometrial cancers, the gene has undergone hypermethylation, an epigenetic modification that doesn't change its DNA sequence but renders it inactive.
Epigenetics refers to reversible modifications to DNA that don't affect the DNA sequence but alter how genes are read.
The alteration of gene activity, called epigenetics, might result from modification of RNA molecules that interact with genes; a modification of the packaging that carries DNA; molecular switches attached directly to the DNA itself; or even something to do with the cell's power - stations, the mitochondria, Baugh said.
The scientists also found that the genes that do not carry either of the two epigenetic modifications are completely silenced in ES cells.
Since the methylation of cytosine does not alter the DNA sequence, but only influences when and where these proteins are produced, it is considered an epigenetic modification.