«A German athletic coach was found attempting to obtain Repoxygen, a gene transfer vector that expresses
the erythropoietin gene [and boosts red blood cell production].
Not exact matches
These included
genes associated primarily with the vascular changes resulting from oxygen deprivation; namely (a) VEGF and its receptors Flk - 1 and Flt - 1 [17,56]; and (b)
erythropoietin (EPO) and its receptor (EPOR)[16].
The
gene for
erythropoietin (EPO), which boosts red blood cells thereby raising blood oxygen and endurance, presents another possibility.
Eero Mantyranta, a Finnish cross-country skier who won two gold medals in the 1964 Olympics, was born with a mutation in the
erythropoietin receptor
gene that allows his blood to carry significantly more oxygen than the average person's [source: McCrory].
Some Web sites claim to sell Repoxygen, a drug that contains the human
gene for
erythropoietin, plus some DNA controlling how it's made, housed inside a virus [source: Frankel].
Dr. Rex used
gene delivery to provide long - term production of a modified form of
erythropoietin (EPO), a hormone that induces red blood cell production but is also a neuroprotective cytokine.
Under hypoxic conditions activates the transcription of over 40
genes, including,
erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other
genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.