Sentences with phrase «estrone pathway»

There is a genetic predisposition to favor one metabolic pathway over another; women with a family history of breast cancer favor the 16a OH Estrone pathway.

Not exact matches

However, 16α - OH estrone is also involved in bone building, so very low levels indicate increased risk for osteopenia / osteoporosis in men as well as women.29303132333435 Confirming this, a positive family history of osteoporosis has been found to be associated with preferential metabolism of estrogen through the inactive 2 - OH pathway.36

(http://joe.endocrinology-journals.org/content/209/3/327/F1.large.jpg) Further down the pathway, estrone and estradiol are made.

When the body tries to metabolize estradiol and estrone it is possible to end up in this pathway which ends up in cancer.