Existing diagnostic screening results for known AD cases (identified through clinical and neuropathological factors), showed diagnostic sensitivity was between 71 percent and 87 percent while specificity ranged from 44 percent to 70 percent.
Not exact matches
Going forward, the development of a reliable
diagnostic kit is much needed to enable hospital, clinic, and public health workers to confirm that patients seeking care are either infected or free of the virus; and while an effective vaccine is being tested, the U.S. Food and Drug Administration should
screen existing antiviral medicines to determine if any can protect people from contracting the virus, Song said.
The researchers point out in their paper that
screening approaches to identify these p53 mutations and others that confer cancer risk already
exist and are used in cancer
diagnostics.
Esko is collaborating with Zacharon Pharmaceuticals, a San Diego - based biotechnology company, to develop a commercial
diagnostic assay for differentiating forms of MPS from urine and blood samples, a
screening test for newborns and a tool for measuring the biochemical response of MPS patients to
existing and novel therapies.