Sentences with phrase «ezetimibe in»

Not exact matches

Instead, ezetimibe blocks dietary cholesterol absorption in the gut by inhibiting the NPC1L1 protein, perhaps approximating the effect of having only one working copy of the NPC1L1 gene.

ORLANDO, Fla. — Adding a pharmaceutical form of the B vitamin niacin — but not the drug ezetimibe — to a cholesterol - lowering statin drug appears to reduce artery plaque buildup in patients with coronary artery disease, according to much - anticipated results announced at a press conference November 15.

The trial was designed to compare outcomes — such as cardiovascular - related death and heart attack — in patients taking a statin plus ezetimibe versus patients taking a statin plus placebo.

Among medications that lower cholesterol, ezetimibe is not in the widely prescribed class of drugs called statins, which stop the body from manufacturing its own cholesterol.

Hearings in January revealed that the release of negative results of a clinical trial of ezetimibe had been delayed.

This was the issue in last winter's congressional investigation into the nonstatin cholesterol - lowering drug ezetimibe, sold as Zetia and contained in Vytorin.

(Ezetimibe on its own is sold under the name Zetia, which was first approved in 2002.)

Ezetimibe works in a different way from statins.

Statins block cholesterol made in the liver, while ezetimibe blocks the absorption of cholesterol in the gut.