Sentences with phrase «ffpe tissue slices»

A tissue slice, a tumor biopsy, or a sample of a bacterial culture yields a sequence representing the average of all of the cells within it, even though researchers know there can be tremendous variation between those cells.

Lena Chin, a graduate student in Slack's lab, sequenced the DNA from the tissue slices.

The team decided to verify that finding by treating tissue slices from developing ferret brains with a chemical that blocks BDNF's activity.

protected animals»); studies on in vitro systems (whole perfused organs, tissue slices, cell and tissue cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).

His work involves high - resolution imaging of chick embryonic tissue slices to study the cell - biological mechanisms driving neurogenesis in the spinal cord, for which Dr. Das played an instrumental role in pioneering new imaging technology.

Her team found evidence of kneecaps in tissue slices from eight frogs, representing several species.

Mouse Pancreas Tissue Slice Culture Facilitates Long - Term Studies of Exocrine and Endocrine Cell Physiology in situ.

In the current study, lead authors David V. Hansen, PhD, a postdoctoral fellow, and Jan H. Lui, a graduate student in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow individual cells and their progeny over time in cultured tissue slices from fetal cortex tissue that had been donated for research.

Marciniak A, Cohrs CM, Tsata V, Chouinard JA, Selck C, Stertmann J, Reichelt S, Rose T, Ehehalt F, Weitz J, Solimena M, Slak Rupnik M, Speier S Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology.

In particular, we use 2D and 3D in vitro cell cultures; tissue slices cultured ex vivo; and transgenic mouse models.

Not exact matches

Finally, the owner of Kleenex tissues is aggressively slicing costs, at a pace of about $ 400 million per year.

Rest the pineapple slices and cherries on a tissue placed over a plate, so that when you use them, the pineapple slice and cherries are not dripping wet.

The tissue thin slices were just right!

Choose a tender steak without much sinew or muscle tissue — flank steak is a great option — and slice it thinly, against the grain, to make it easy to eat.

The animals» cellular scaffolding, or cytoskeleton, can regrow from a slice of tissue that's just 2 percent of the original hydra's full body size.

She has also started slicing open the lanternfish so she can determine if they are eating plastic and whether POPs are accumulating in their tissues.

You can visit them there, where you can also see a tumor removed from Grover Cleveland's mouth; a slice of tissue from the chest of John Wilkes Booth; the shared liver of the famous conjoined («Siamese») twins Chang and Eng Bunker; and a collection of cysts, tumors, and deformities of all sorts.

The quantity of protein clumps was calculated using a computer program that measured the amount of tissue in a skin slice with protein clumps expressed as a percentage of the tissue's total area.

In an analysis of Medicare billing data submitted by more than 2,300 United States physicians, researchers have calculated the average number of surgical slices, or cuts, made during Mohs micrographic surgery (MMS), a procedure that progressively removes thin layers of cancerous skin tissue in a way that minimizes damage to healthy skin and the risks of leaving cancerous tissue behind.

After slicing open some of the crocodile corpses last year, researchers determined some kind of pansteatitis — an inflammation of adipose tissue — was killing the animals.

Indeed, by examining brain tissue and slices from the cocaine - addicted rats at various stages of withdrawal and craving, Wolf and her colleagues discovered that the incubation period and the subsequent spike in craving appeared to correlate with the appearance of atypical AMPA receptors on the surface of neurons in the NAc, which could help explain cocaine craving.

Scientists at the Allen Institute for Brain Science in Seattle are using microscopy to directly observe gene activity, one at a time, in razor - thin slices of mouse brain tissue.

Brain tissue is spread out over the table in neat 10 millimetre slices, like some kind of macabre deli counter.

In this study, the researchers from Imperial's Department of Surgery and Cancer and the Royal British Legion Centre for Blast Injury Studies, applied xenon to slices of mouse brain tissue after exposing them to blast shockwaves that emulated those produced by improvised explosive devices (IEDs).

The tissue is then taken to a processing center, where the materials are given a thorough cleaning and techs slice off excess pieces of muscle or bone before they cryopreserve them, which keeps the remains usable in living patients for up to five years.

In 1898, Italian biologist Camillo Golgi saw something odd in the slices of brain tissue he examined under his microscope: weblike lattices surrounding many neurons.

To map the roughly 1300 connections, or synapses, between the cells, researchers used an electron microscope to take millions of nanoscopic pictures from a speck of tissue not much bigger than a dust mite, carved into nearly 3700 slices.

SUSHI also visualizes synaptic clefts for the first time in slices of live tissue and reveals glia - neuron interactions and cell migration.

To test his theory, he looked at slices of human brain tissue.

In the 19th century it was tackled by slicing the cords of tissue underneath the tongues of puppies.

The Slice Once the gelatin sets, the brain is frozen, mounted on a motorized tissue - slicing device called a microtome, and sliced.

They then kill the animal and slice its brain tissue thin enough so that light can shine through it under a microscope, revealing the structure within each slice.

During the spring and summer of 2009, Annese and his collaborators tinkered with the equipment needed to dissect H. M.'s neural tissue into precise slices.

As the motorized stage moves backward, a razor - sharp blade peels away a 70 - micrometer - thick slice of tissue — like prosciutto at the deli counter, only far thinner.

Fossilized slices of a 374 - million - year - old tree reveal a hollow core surrounded by numerous bundles of woody strands called xylem (the larger black spots), with soft tissue (in gray) between.

Gobbling a slice of sweet pumpkin pie, for instance, causes beta cells in the pancreas to secrete insulin, a hormone that allows the uptake of glucose and most amino acids into the tissues.

To make such a detailed model, researchers took specks of brain tissue and cut them into slices thousands of times thinner than a human hair.

va Mezey of the NIH did the job by staining the same slice of tissue in two ways, once to pinpoint the secretion (either of insulin or of saliva) and a second time to pinpoint the male, or Y, chromosome.

In their most recent work, Walker and colleague Carol Diebel turned to a magnetic force microscope, running it less than a hair's width above thin slices of trout nose tissue.

The mouse atlas was produced using a method called «in situ hybridisation», in which thin slices of brain tissue are bathed in a solution containing molecular probes that bind to messenger RNA sequences produced by each gene.

Bova has come up with a novel application of 3 - D printing that lets neurosurgery residents slice into realistic skulls and brain tissue with zero risk.

Here at the Harvard Brain Tissue Resource Center, donated specimens are sliced up, preserved, stored, and eventually parceled out to neuroscientists worldwide who study them for clues to disease, cognition, and the mysterious cellular underpinnings of psychology.

Next, Südhof's team examined slices of brain tissue from the mutant mice.

To understand more, she conducted experiments in acute brain slices, small pieces of brain tissue where neurons stay alive and maintain their physiological properties.

In order to preserve the tissue, samples are taken and usually fixed with formalin, before they are embedded in wax - like paraffin and cut into razor - thin slices.

It involves flash - freezing tissue or cells, then cutting thin slices of individual nuclei.

In many forms of traditional biomedical microscopy, light is shined through very thin slices of tissue to produce an image.

Lasers are used to cut metal, slice through tissue during surgery, trap atoms, and even initiate nuclear fusion.

Another Kavli researcher, Steven Siegelbaum, uses a technology called two - photon microscopy to image pre-synaptic terminals (the nerve cell tips that send charges from one cell to another) within slices of living brain tissue.

Distinguishing between different types of endometrial cancers is currently based on histology, an examination of a thin slice of tissue under a microscope.