A research team from the University of Basel's Biozentrum has now discovered how bacteria enter a sleep mode using a so - called
FIC toxin.
Next, Dehio's team aims to elucidate the evolutionary link between these original
FIC toxins and the FIC proteins, which are injected as virulence factors into host cells by diverse pathogens.
Not exact matches
Prof. Christoph Dehio's research group at the Biozentrum, University of Basel, has uncovered a new mechanism of action of
toxins from the group of
FIC proteins.
Dehio's team now first discovered such
toxins among
FIC proteins that can be found in all domains of life and demonstrated that they act by altering cellular DNA.