Sentences with phrase «fat cells reprogrammed»
«Fat cells reprogrammed to increase fat burning.»
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«The discovery of the «brite» fat cell mechanisms and the specific regulatory areas brings us closer to understanding how reprogramming of white fat cells takes place.
The research team from the Department of Biochemistry and Molecular Biology headed by Professor Susanne Mandrup are publishing a paper entitled «Browning of human adipocytes requires KLF11 and reprogramming of PPAR super-enhancers» in the January 1 edition of the scientific journal Genes & Development that describes their results from working with «brite» fat cells.
«By identifying the areas of the genome that are directly involved in the reprogramming, we have also identified an important factor in the process — the gene regulatory protein KLF11 (Kruppel Like Factor - 11), which is found in all fat cells, and we have shown that it is required for the reprogramming to take place.»
The challenge is to reprogram the energy storing white fat cells into so - called «brite» (brown - in - white) fat cells in the body's white adipose tissue and thus make adipose tissue burn off excess energy as heat instead of storing it.
Now researchers from the University of Southern Denmark have uncovered the mechanism by which white fat cells from humans get reprogrammed to become browner.
These stem cells, which are similar to highly sought - after embryonic stem cells but derived from adult cells and then reprogrammed, could be turned into the cell types needed for research, including neurons and intestinal and fat cells.
In one study, geneticist Joseph Ecker at the Salk Institute in California took various stem cell lines reprogrammed from skin, fat, and other tissues and examined each line's genome for dna methylation, chemical marks that alter how genes are expressed.
The team learned that the cells from the group of obese patients suffering from type 2 diabetes had been reprogrammed and therefore did not function like normal, healthy fat cells.
But until now no one has been able to identify the factors affecting the reprogramming of precursor fat cells or establish the rapidity at which cells are reprogrammed.
This is all it takes for a so - called precursor fat cell to have its «epigenetic recipe» on how to correctly develop into a mature fat cell, reprogrammed.
«We know that these fat cells are multipotent, which should [make it] easier to reprogram them,» Wu says.
Sun found that the fat stem cells actually express higher starting levels of two of the four reprogramming genes than do adult skin cells — suggesting that these cells are already primed for change.
«When you eat that kind of diet, insulin levels decrease and you reprogram your fat cells to release excess calories,» says Dr. Ludwig.
New science shows that you can eat to reprogram your fat cells and slim down for good.
His program helped me reprogram my metabolism and cells to become a fat burning machine.