In previous roles, Dr Haley made significant contributions to the FedSat
microsatellite mission.
Vector provides affordable and reliable access to space by combining dedicated
microsatellite launch and software - defined satellites.
Aborted launch of
microsatellite this morning is latest failure for nation's space scientists
In contrast, mitochondrial DNA (mtDNA) markers tend to mutate more slowly than
microsatellites, often including variation specific to a particular species rather than an individual or population.
Although a variety of molecular methods are still in use,
microsatellite DNA markers have become the marker of choice for population studies.
Others, such as a new
microsatellite system aiming to improve measurements of hurricane intensity and a highly anticipated new computer simulation that forecasts hurricane paths and intensities, are still in the calibration phase.
By examining bits of DNA called
microsatellites, which mutate rapidly, Goossens was able to trace individual genetic differences back to a common ancestor and estimate the size of the orangutan population at different times in the past.
In much the same way that forensic scientists compare DNA samples to catch criminals, the New Mexico researchers compared 619 «
microsatellite» positions on genomes, creating a digital evolutionary tree of the groups.
The population - based study of 503 people with colon cancer found that 14 percent of Caucasians and 7 percent of African - Americans had a genetic marker called
microsatellite instability, or MSI.
They used sequences of maternally inherited mitochondrial DNA and «
microsatellite genotypes,» or DNA profiles, to both describe the genetic differences and outline migratory connections between both breeding and feeding grounds.
For the new study, which is published today in the Proceedings of the Royal Society B, Bowman and his colleagues collected samples from 38 L. mariae palms in Palm Valley and 100 L. rigida palms in the Roper, Nicholson, and Gregory rivers and compared
the microsatellite markers.
Touboul is the project scientist for MICROSCOPE,
a microsatellite to be launched in 2007 by the European Space Agency.
So the Kyoto researchers developed a set of
microsatellite markers, short bits of repeated sequences of DNA that tend to evolve very quickly.
Extra bases are easily added or lost when the DNA is copied, so the number of repeats in each of these stretches, known as
microsatellites, varies widely from one individual to another.
By matching
microsatellite lengths found in acorns against those of all the adult trees in the stand, Dow was able to identify the father of each acorn with a high degree of certainty — if the father was present in the stand.
A team of scientists led by Aarhus University mapped the migration patterns, centre of diversity and population structure of this aggressive fungus using
microsatellite genotyping of worldwide representative samples.
Funded by the National Zoological Gardens of South Africa, Rufford's Small Grants for Nature, and the National Geographic Society, Parusnath is developing and testing
microsatellite markers similar to those used in human parentage tests to establish the genetic relatedness of Sungazers in different populations across the species» distribution.
In the largest study of its kind to date, researchers used mitochondrial DNA
microsatellites from skin samples gathered from more than 3,000 individual humpback whales across the Southern Hemisphere and the Arabian Sea to examine how whale populations are related to one another, a question that is difficult to answer with direct observations of whales in their oceanic environment.
A microsatellite is a short, repetitious sequence of DNA — CACACACA, for instance — in which the number of repetitions can change from one generation to the next and often does.
His team sampled 22 bedbug populations from nine states along the U.S. East Coast and examined nine so - called
microsatellites, highly variable pieces of DNA that are particularly helpful in understanding genetic differences between populations.
While Wells screened the Central Asian Y chromosomes for single - nucleotide mutations such as M45, Zerjal searched for a different DNA variable called
a microsatellite.
The goal was to see if a mother ship
microsatellite could launch smaller daughter ships, with all the satellites capable of sending magnetic field measurements to Earth.
They also took a so - called
microsatellite DNA fingerprint.
That's why a particular pattern of
microsatellites can profile a particular individual — to show, for instance, as Tyler - Smith and Zerjal had done shortly before embarking on their Central Asian work, that Thomas Jefferson had fathered a son by his slave Sally Hemings and that his Y chromosome had been passed down to a man living in Pennsylvania today.
In 1999, Robert Twiggs, an astronautical engineer now at Morehead State University, helped create the Orbiting Picosatellite Automatic Launcher (OPAL),
a microsatellite that can propel several satellites as small as ice cream bars into space.
But the chance that a given
microsatellite will change from, say, 11 CA (cytosine and adenine) repeats to 12 is on the order of one in a few hundred.
«
Microsatellite length and location appears to be essential for EWS / FLI to activate the oncogenic gene targets,» says Dr. Lessnick.
«Our results have revealed and characterized two classes of GGAA -
microsatellites that suggest unique interactions and distinct regulatory mechanisms for distance - dependent activation and repressions.
Overall it has participated in more than 300 space missions, providing everything from Internet - controlled
microsatellites to hybrid propulsion systems and space vehicles.
«Two classes of GGAA -
microsatellites in a Ewing sarcoma context: Characterization of GGAA -
microsatellites provides insight in the role of noncoding DNA in cancer susceptibility and therapeutic development.»
That data revealed two distinct types of GGAA -
microsatellites: «promoter - like» (close - range) and «enhancer - like» (long - range).
Then, they computationally linked bound
microsatellites to adjacent EWS / FLI regulated genes.
Further investigation into how EWS / FLI associates with GGAA -
microsatellites to drive transcription was the subject of a recent study published in Proceedings of the National Academy of Sciences.
This characterization contributes insight into EWS / FLI transcription factor biology and clarifies the role of GGAA -
microsatellites on a global genomic scale.»
According to the study, EWS / FLI binding and gene activation at promoter - like
microsatellites is highly dependent on the length of GGAA motifs.
Both studies highlight the importance of
microsatellite length in oncogenic function.
At long range, enhancer - like
microsatellites demonstrate length - dependent EWS / FLI binding, but the researchers found minimal correlation for activation and none for repressed targets.
The distance between these neighboring sequences, called primers, differs between each individual coral due to the number of times
the microsatellites are repeated, providing valuable information on the relatedness of different individuals.
In order to detect
microsatellites commonly present in the two Acroporaspecies used in the study, the researchers used a process called polymerase chain reaction (PCR), using a pair of flanking DNA sequences that extend to either side of the microsatellite region.
The Microsatellite Center is a high - throughput genotyping laboratory dedicated to mapping monogenic and especially polygenic factors with linkage analysis by using fluorescent detection of microsatellites.
Another breakthrough came a few years later with the discovery of «
microsatellites», short sequences of two to four nucleotides.
The researchers found no differences in the mitochondrial DNA from North American pumas, and
their microsatellites were «virtually indistinguishable,» NCI's Melanie Culver reported at the meeting.
Microsatellites are a gene mapper's dream: not only are they repeated different numbers of times in different people, but they are scattered throughout the genome.
However, the development of
microsatellite DNA markers remains time consuming, expensive, and labor intensive since the markers are often species specific.
As a young Chinese scientist, I am participating in an exchange program with Germany, having joined the Chinese - German
microsatellite genome research project at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany.
After extracting tiny amounts of ancient DNA from the mummies» bones, the researchers amplified 16 short tandem repeats (short sequences in the DNA that create a genetic fingerprint) and eight polymorphic
microsatellites (hereditary molecular markers) to testable quantities using techniques commonly employed in criminal or paternity investigations.
In 2017, the U.S. Food and Drug Administration (FDA) approved the cancer drug Keytruda (pembrolizumab) for a range of solid tumors that are
either microsatellite instability - high (MSI - H) or mismatch repair deficient (dMMR).
For the study, an international team of researchers based at institutions in Spain, the United States, Canada and Australia used mitochondrial DNA and
microsatellite genotypic data to investigate the levels of genetic variation and to reconstruct the history of the invasions.
The beauty of
microsatellites is that they mutate frequently and at a steady pace, enabling scientists to infer from them when human populations first diverged from each other.
So the scientists caught blackcaps when the birds returned to Germany in the spring and sequenced short stretches of their genomes called
microsatellites.