Sentences with phrase «fetal brain model»

«Zika virus may cause microcephaly by hijacking human immune molecule: Fetal brain model provides first clues on how Zika virus blunts brain development; blocking mechanism reduces cell damage.»

Not exact matches

Neurospheres and brain organoids represent excellent models to investigate developmental neuropathologies, as they can outline, in vitro, several characteristics of the fetal brain formation.

The multinational research group utilized a model system where human retinal pigment epithelial cells were infected with Zika virus strain they isolated earlier from fetal brain [T1].

Mice given alcohol just after birth are a good model for measuring the impact on human fetal development because the brains of mice pups achieve developmental milestones after birth that are comparable to those in other mammals, including humans.

They found that, genetically speaking, their organoid model closely resembled fetal brain tissue at eight to nine weeks post-conception.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

It takes about 15 weeks to build a model system developed to match the five - week - old fetal human brain.

NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.