Hereditary
footpad hyperkeratosis is an autosomal recessive skin condition found in certain breeds of dogs in which the foot pads become hardened, losing their normal elasticity, developing painful cracks that are prone to infections that can lead to lameness.
The end result of the research was that there was a common gene mutation that was responsible for
footpad hyperkeratosis in all the breeds involved in the research project.
However, in August 2008 Professor Tosso Lieb and a team of geneticists at the University of Berne, in conjunction with ANTAGENE, started a research project to analyse the genomes of a number of breeds of dog (including the Irish terrier, but not the Bedlington terrier) in which
footpad hyperkeratosis was a problem.
Furthermore,
footpad hyperkeratosis as recently been confirmed as a genetic disorder.
Not exact matches
Other dogs develop
hyperkeratosis, or abnormal, hard skin growths on the
footpads and nose.
Nasodigital
hyperkeratosis is a disorder characterized by excessive growth of the epithelium of the nose and
footpads.
In some cases,
hyperkeratosis of the nose and
footpads may be seen (the nose and
footpads become very thickened and cracked — see photo).