In recent years it was also observed that it can function as a metabolic «signaler» that inhibits a biological pathway found in almost all higher life forms — the ability to sense when food has been eaten, energy is available and it's
okay for cell proliferation, protein synthesis and growth to proceed.
Our data support previous studies that there is a greater
potential for cell proliferation in the periphery of the corneal endothelium than in the central corneal endothelium.
The authors found that adjusting breast cancer expression
data for this cell proliferation signature causes a dramatic reduction in outcome association of most published breast cancer signatures (Venet et al., 2011).
In addition to its structural role in epithelial junctions, beta - catenin activates TCF -4-mediated transcription of genes
required for cell proliferation.
It's now extensively recorded that under suitable conditions, glutamine is
important for cell proliferation, that it can act as a respiratory system fuel and that it can enhance the function of stimulated immune cells.
For cell proliferation assay, 5 × 104 cells were seeded in triplicate wells per cell line per time point in 12 - well tissue culture plates.
«
For cell proliferation, each drug's dual action is like both easing off the accelerator and depressing the brake pedal.»
We plan to add to the current manuscript our data from knockout mice, to strengthen the point that MELK is not a universally essential gene
for cell proliferation and only selectively required in basal - like breast cancer.