Sentences with phrase «functional studies show»

Moreover, functional studies show that EZH1 mutations modify signal pathways that cause thyroid cells to proliferate.

Not exact matches

The method identifies gene sets that show evidence for positive selection in comparison with matched controls, and thus highlights genes for further functional studies.
A study shows, for the first time, how these functional impairments arise: Social isolation during early life prevents the cells that make up the brain's white matter from maturing and producing the right amount of myelin, the fatty «insulation» on nerve fibers that helps them transmit long - distance messages within the brain.
Researchers at Umeå University in Sweden, together with researchers at Institute of Botany, Chinese Academy of Sciences, show in a new study how natural selection drives functional evolution of a large protein family in conifer trees.
«Moving forward, we'll need to conduct additional studies of many more patients to show that getting functional scans in the first hours or days after a stroke could provide valuable information for predicting outcome and tracking recovery.»
«There has been little evidence to date that the environmental services provided by tropical forests are really conditional on fully functional forest ecosystems that can retain a full complement of wildlife species, but this study shows that biodiversity and natural ecosystem services are inextricably linked.
The proteins we identified seem to be involved in fundamental developmental processes and we hope that functional studies will show that some of them are ideal candidate targets for the design of new and selective inhibitors.»
In 2015 Oxford pediatric neuroscientist Rebeccah Slater and her colleagues published a pioneering functional magnetic resonance imaging (fMRI) study showing infants» brains respond to painful stimuli very similarly to those of adults.
«However, studies have shown that HDL doesn't work as well in people at high risk for heart attacks, strokes and other cardiovascular diseases, and that the functional ability of HDL matters as much as its quantity,» said senior study author Montserrat Fitó, M.D., Ph.D., and coordinator of the Cardiovascular Risk and Nutrition Research Group at the Hospital del Mar Medical Research Institute in Barcelona and at the Ciber of Physipathology of Obesity and Nutrition (CIBEROBN), Spain.
Our new study has shown that we can go even further: from these co-mutations it is possible to uncover the protein's macrostructure, its fundamental structural and functional units.»
However, Holt's study also showed that gene therapy with TMC2 could compensate for loss of a functional TMC1 gene, restoring hearing in the recessive deafness model and partial hearing in the dominant deafness model.
A team of researchers led by Rodrigo Lacruz, MSc, PhD, assistant professor in the Department of Basic Science and Craniofacial Biology at NYU College of Dentistry, has published a paper in Scientific Reports (5:15803) titled «Dental enamel cells express functional SOCE channels,» which reports the results of a study showing for the first time the mechanism of calcium transport essential in the formation of dental enamel.
The researchers believe this study is the first one to show clear functional changes that transfer into surgical skill in individuals who had simulator training.
An August 15 functional MRI study in NeuroImage shows that in CG patients reminders of the deceased activate a brain area associated with reward processing, pleasure and addiction.
They also published findings from an animal study showing that the effect of stem cell therapy following heart attack is indirect — the stem cells themselves do not survive long after being placed in the heart, but they cause enduring effects by stimulating the rapid growth of surviving heart tissue and attracting stem cells already in the heart, which mature into functional heart cells.
Over the past few years, different studies have shown that the inflammatory response that develops after an injury contributes to the degeneration of these pathways, thus increasing the functional deficits brought by the injury.
Because aerobic exercise has been shown to lead to improvements in processing speed and functional changes within the frontal and other brain regions, it was included as one of the study groups.
An analysis of diagnostic test results from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial — in which patients with stable chest pain were randomized to either anatomic or functional testing as an initial diagnostic strategy — showed that the presence and extent of coronary artery disease detected by CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.
The study also showed concomitant improvement in other measures of functional status and quality of life among those treated with FCM compared to placebo.
Previous studies have used functional magnetic resonance imaging (fMRI) scans to show that similar areas of the brain are activated when someone is in pain and when they see another person in pain.
In their study the researchers showed different characters to test persons and recorded via functional magnetic resonance imaging the brain activity which was set into motion by the process of seeing.
Results of a research study published in the journal Functional Ecology show that the early bird is so productive, it results in greater numbers of offspring.
«This functional MRI study provides the first objective evidence showing the exact malfunctions in the brain's memory circuits that underlie these chemically induced memory problems.»
One recent study showed that sleep - deprived subjects experienced a loss of functional connectivity between the amygdala and the medial - PFC compared to controls.
A study of the long - lived seabird, the European shag, published in the journal Functional Ecology shows that parental age may affect how long offspring live.
Although the functional territories of the human PAG are difficult to dissociate and should be interpreted with caution, our study shows that both the ventral and dorsal portions of the PAG were active during the AI condition.
«Our finding of a link between bipolar disorder and the striatum at the molecular level complements studies that implicate the same brain region in bipolar disorder at the anatomical level, including functional imaging studies that show altered activity in the striatum of bipolar subjects during tasks that involve balancing reward and risk,» said TRSI Research Associate Rodrigo Pacifico, who was first author of the new study.
Previous studies had shown that if you cut a Stentor cell in half, each cell fragment will regenerate into a fully functional cell with a mouth and tail.
However, while other studies have shown that around 5 - 8 % of the genome is conserved at the level of DNA sequence, indicating that it is functional, the new study shows that in addition much more, possibly up to 30 %, is also conserved at the level of RNA structure.
Functional imaging studies have also shown that autistic minds show decreased activity and connectivity in areas of the so - called «social brain» — regions important for language, face recognition and emotion.
Now a functional magnetic resonance imaging (fMRI) study shows where in the brain the confirmation bias arises and how it is unconscious and driven by emotions.
«This study for the first time shows increased expression of IL - 33 in AMD and further demonstrates a role for glia - derived IL - 33 in the accumulation of myeloid cells in the outer retina, loss of photoreceptors, and functional impairment of the retina in preclinical models of retina stress,» the authors note.
In the first study of functional immunity to Campylobacter jejuni in the chicken, researchers have shown that antibody production plays a role, albeit limited, in the clearance of intestinal infection.
Vanhatalo points out that functional MRI imaging does not show the functional coupling of an infant's neurons, even though the method is still widely used all over the world for studying this very phenomenon.
Functional magnetic resonance imaging (fMRI) used in the study showed activity in a part of the brain called the ventral striatum — which has been shown to guide goals based on prior experiences.
A study just published in Scientific Reports shows that these differences go hand in hand with differences in the patterns of integration among functional modules of the brain.
But other studies of rodents continue to be published that do show developmental and functional abnormalities at low doses, including at doses significantly below those found in humans.
Recent studies have shown that the functional connections of the brain network are organized in a highly efficient small - world manner (Sporns et al., 2004; Stam, 2004; Eguíluz et al., 2005; Achard et al., 2006; van den Heuvel et al., 2008b).
In summary, the results of this study show the potential for functional MRI to bridge the dissociation that can occur between behavior that is readily observable during a standardized clinical assessment and the actual level of residual cognitive function after serious brain injury.14 - 16 Thus, among 23 patients who received a diagnosis of being in a vegetative state on admission, 4 were shown to be able to willfully modulate their brain activity through mental imagery; this fact is inconsistent with the behavioral diagnosis.
These studies, showing the functional effects of CTLA - 4 Ig as a potential tolerogen, [i] led to the discovery of CD86 [ii] and the development of the first costimulation blockade (Abatecept).
Previous SAR studies on pentapeptides showed that at least three functional groups on the peptide side - chains are required: an aromatic ring (such as 2 - naphthyl - or 3 - indolyl group), one or two guanidino groups, and a phenol group.
In most clinical studies, women with T2DM show a higher burden of risk factors and comorbidities as well as more cognitive and physical functional limitations than males do (335, 336).
These studies showed not just proof of concept of a new technology, but a spectacular jump in what is possible within functional genomics.
All studies examined show largely convergent results: the strength of resting - state functional connectivity is positively correlated with structural connectivity strength.
Functional magnetic resonance imaging (fMRI) studies have tended to show limited activation in the anteriormost regions of the hippocampus, providing support for the Moser and Moser model.
Recent studies have shown that it is possible to reliably identify this network in the absence of any task, by resting state functional magnetic resonance imaging connectivity analyses in healthy volunteers.
In this study, we show that DMN functional connectivity (FC) during rest is altered with increasing levels of PIB uptake in NC.
Further studies showed that Notch1 knockdown in NSCLC helps induce cell death (which inhibits tumor initiation and growth); this process is mediated by p53, and thus the effects of inhibiting Notch1 require functional p53.
Research is beginning to show the connection In a 2005 study, researchers at Stanford University in Palo Alto, Calif., used functional magnetic resonance imaging (fMRI), which measures activity in different areas of the brain, to see whether subjects could learn to control a brain region involved in pain and whether that could be a tool for altering their pain perception.
The beautiful thing is that when we restore vitality and energy, the human body shows its amazing capacity to healMy approach is based on my education at The Institute for Integrative Nutrition where I studied over 100 different dietary theories and learned from some of the best minds in nutrition and functional medicine.
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