Also, the methodology allows measuring
biochemical reactions
far from the surface, avoiding one of the main limitations of classic SM methods, i.e., the need for immobilization of the molecules under
study on a surface (glass slide or microspheres).
Further studies are required to confirm the findings of Ott et al. and to determine if patients with hypothyroidism due to Hashimoto's thyroiditis still have residual symptoms despite achieving an ideal
biochemical response to thyroid hormone replacement therapy.»