Not exact matches
«
Future studies will aim to explore the relationship between SND1 and STAT3, identify additional microRNAs that may be relevant to malignant glioma and explore the effects of drugs that block SND1 expression in more advanced
preclinical models.»
According to the authors of the study, in
future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden
preclinical studies with laboratory animal
models.
Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing
preclinical models and guidance on standard operating procedures for ancillary or
future studies in identified population at risk.
Now, three papers published concurrently in Science have shown CRISPR can treat a genetic disease in a postnatal mouse
model, an important proof of concept for
future preclinical and clinical work.