Sentences with phrase «glk2 transcription factor genes»

Furthermore, GNC and GNL act, at the gene expression level, in an additive manner with the GOLDEN2 - LIKE1 (GLK1) and GLK2 transcription factor genes, which are also important for proper chlorophyll accumulation.

Additional gene duplication and divergence in eumetazoans further increased transcription factor gene family number, which in general are 2 to 34 times larger in eumetazoans than in Amphimedon.

Developmental expression of transcription factor genes in a demosponge: insights into the origin of metazoan multicellularity.

Out of a total of five positively selected SNPs, four represented nonsense mutations resulting in stop codons, three of these in a single ApiAP2 transcription factor gene, and one in SRPK1.

A piebald dachshund puppy shows up only when both parents who carry the microphthalmia associated transcription factor gene are bred.

Not exact matches

Transcription factors are proteins that «turn on and turn off» genes.

Adding seven transcription factors — proteins that switch on genes — the team then converted the IPSCs into immature HSC - like cells.

The ATF6 protein is a transcription factor, meaning it helps turn other genes «off» or «on,» depending on what's needed by the cell.

In all the pathways so far investigated, the final result is a gradient of morphogen that functions principally as a transcription factor, initiating or suppressing the transcription of one or more target genes in a concentration - dependent manner.

The gene encodes a transcription factor, a protein that in this case binds to DNA and allows it to be read out as messenger RNA.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

M. J. Bertram et al., Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor - like genes.

They noted that Tregs generally had high levels of a protein called Helios, a transcription factor that helps switch genes on and off.

The activity of four transcription factors — proteins that regulate the expression of other genes — appears to distinguish the small proportion of glioblastoma cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kiTranscription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kitranscription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kitranscription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown gene that appears to code for a transcription factor — a protein that switches other genes on or off.

The guilty protein is beta - catenin, a transcription factor which activates other genes.

One encodes retinoid - related orphan receptor alpha (RORα), a transcription factor that itself regulates multiple other genes.

Aiolos is a member of a class of proteins called transcription factors — proteins that control which genes are turned on or off by binding to DNA and other proteins.

A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins.

SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.

Hockemeyer says that it's unlikely to be another mutation, but rather an epigenetic change that affects expression of the telomerase gene, or a change in the expression of a transcription factor or other regulatory proteins that binds to the promoter upstream of the telomerase gene.

In the paper, the researchers illustrate how it could influence proteins that activate the transcription factors that transcribe major bone - related genes to drive bone formation — showing a link between metabolite usage and activation of transcription factors.

In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.

Others have tracked the first few hours of the embryonic development of sea urchins and other organisms with the goal of seeing how various transcription factors alter gene expression over time.

Transcription - factor genes code for proteins that regulate the activity of other genes and so affect an animal's ability to respond to its environment.

Spalax naturally have a variant in the p53 gene (a transcription factor and known tumor suppressor), which is identical to a cancer - related mutation in humans, Band said.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

Other proteins, called transcription factors, interact with the genes more directly: They bind to landing sites situated near the gene under their control.

The oxidation status of STAT3, in turn, determined how efficiently the transcription factor regulates gene activity.

Furthermore, they found that the Sp7 transcription factor directly controlled gene expression of the Fgf ligands.

Disease processes often begin with mutations in the transcription factor, or in the DNA they bind to inside the nucleus of cells to regulate the complex interplay of genes needed for a healthy functioning body.

Transcription factors are proteins that interact with DNA to turn genes on or off.

Wyrick and his colleagues also saw less damage around transcription factors, proteins that bind to specific, short stretches of DNA and regulate gene expression by controlling which genes are turned on and off.

In most cases, the genes responsible for these processes are known as «transcription factors» — meaning that they are responsible for turning other genes on and off.

By studying Arabidopsis plants for which the genes for these transcription factors had been selectively knocked out, the group identified a single transcription factor that when inactive resulted in longer roots.

If an engineered organism mates with a wild counterpart, the transcription factors render the offspring unable to survive by activating genes that cause their cells to die.

We know that Hox genes encode transcription factors that control the activity of other genes, but we found that digit - innervating motor neurons also express other genes, such as FIGN and CNEP4], and we still don't know the function of any of these other genes.

Based on previous work, the researchers had reason to think it was controlled by transcription factors — proteins that control the expression of certain genes by binding to DNA at specific locations to induce (or block) the transcription of information from DNA to RNA.

Unlike most proteins, those with these special domains can actually bind to DNA and act as transcription factors — telling specific genes to turn on or off.

They tested their system on a pair of yeast transcription factors and used the data to predict which yeast genes the proteins would target, they report in this week's Science.

This will enable an array of factors to position themselves on the activated gene and to initiate its transcription,» says the PhD student.

The genes — Oct 3/4, Sox2, c - Myc and Klf4 — are molecular switches called transcription factors, which activate other genes in series like a power strip.

Genes become more or less active at the touch of proteins called transcription factors, each of which can influence hundreds or thousands of other gGenes become more or less active at the touch of proteins called transcription factors, each of which can influence hundreds or thousands of other genesgenes.

All of these genes code for transcription factors, which are proteins that control the expression of other genes.

Glk1 is a transcription factor, meaning it binds to specific regions of DNA and activates genes involved in cell death and other plant immune responses.

After receiving a signal that tells a transcription factor called GABP to bind the Terf2 gene.

Using the recently completed tomato genome sequence they then identified the gene as SlGLK2 — a so - called transcription factor, which controls when and where other genes are switched on or off.

Thus, this cDNA derives from a gene (oct - 2) that specifies an octamer binding protein expressed preferentially in B lymphocytes, proving that, for at least one gene, a cell - specific transcription factor exists and its amount is controlled through messenger RNA availability.

We had started working on this more than a year ago, when we tried inserting four transcription factors, which regulate genes, into the skin cells.