The sequence of the strands is designed to knock down the GM3
synthase gene.
On the research applications front, Dr. Chia Tet Fatt, a young scientist from the Natural Sciences Academic Group at the National Institute of Education, revealed Singapore's very first genetically modified organism (GMO)-- a transgenic resveratrol producing red lettuce for the prevention of cancer and cardiovascular diseases — which was developed by introducing the stilbene
synthase gene into a red plant and diverting the precursors into resveratrol synthesis.
Regulation of fatty acid
synthase gene transcription.
Defense: «Effects of canopy cover and pH on polyketide
synthase gene transcription in Cladonie stygia and the polyketides produced in natural conditions.»
, Angelica sinensis polysaccharides stimulated UDP - sugar
synthase genes through promoting gene expression of IGF - 1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity, 2014
Hendrickson, L. Davis, C. R. Roach, C. Nguyen, D. K. Aldrich, T. McAda, P. C. and Reeves, C. D. Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide
synthase gene.
They combined the phytoene
synthase gene from maize with crt1 from the original golden rice.
Not exact matches
The genetically modified organism (GMO) is wheat Triticum aestivum, which has been transformed with one or both of the following synthetic
genes: (E)- β - farnesene
synthase and farnesyl diphosphate
synthase.
«Most interestingly, we found a similar dynamic, or circadian, looping when we studied a
gene called Glycogen
synthase 2,» says Felix Naef.
«We discovered a very interesting
gene that's called lycopaoctaene
synthase, or LOS.
But polyketide
synthases don't work without a co-factor called phosphopantetheine, so the researchers also introduced a
gene from the soil bacterium Bacillus subtilis that encodes the enzyme that attaches phosphopantetheine to the polyketide
synthase.
They first introduced three
genes from a soil bacterium called Saccharopolyspora erythraea, which together produce an enzyme called a polyketide
synthase, which produces one particular polyketide.
The team eliminated three of the four known starch
synthases by inserting backward copies of the
genes for each one into the potato genome, which, through an unknown mechanism, interferes with the translation of the nearby normal
gene.
The expression of mRNA for factors involved in promoting mitochondrial biogenesis, including the transcription factor Ppard, the PPARδ coactivator Pgc - 1α, and citrate
synthase was greater in gastrocnemius muscles from IL - 15Rα — KO relative to B6129 control (Figure 5C); however, levels of these
genes were unchanged in spleen and kidney (data not shown).
(C)
Gene expression was greater for Ppard, Pgc - 1α, and citrate
synthase in muscles from IL - 15Rα — KO mice, as determined by qPCR.
Two of these SNPs are within a single
gene, which codes for the enzyme nitric oxide
synthase 2 (NOS2).
A homologue of the 3 - oxoacyl -(acyl carrier protein)
synthase III
gene located in the glycosylation island of Pseudomonas syringae pv.
A transcriptome research of its organs revealed its
gene signature is highly evolved and adapted for extreme longevity (slow metabolism, improved insulin
gene signaling and glucose homeostasis, thus reduced blood glucose, improved cancer
genes, improved endothelial function by eNOS (endothelial Nitric Oxide
Synthase) meaning improved vascular coronary blood flow, improved microvasculature arterial and heart endothelium function) but more importantly, to answer your question, some whales display low blood glucose hypoglycemia, this affects the quantity and period of proteins / DNA / cell exposure to glucose glycation, glycosylation and glycoxydation reactions.
Characterization of the hcnABC
gene cluster encoding hydrogen cyanide
synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0.
Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen
synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate
synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1
gene 1; NOS, nitric oxide
synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated
gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting
The most abundant resistance
gene was sul2, which encodes for a sulfonamide resistance variant of dihydropteroate
synthase — an enzyme essential for folate synthesis [25].
Reactivation of methionine
synthase from Thermotoga maritima (TM0268) requires the downstream
gene product TM0269.
High levels of
gene expression were found in both strains for
genes involved in growth, energy and respiration (e.g., ribosomal proteins, ATP
synthase, pseudoazurin), and the C - 1 metabolic carbon such as methanol dehydrogenase, ribulose monophosphate enzymes (D - arabino -3-hexulose 6 - phosphate formaldehyde - lyase, 6 - phospho -3-hexuloisomerase), formaldehyde activating enzymes (Data S6, Fig.
Even more encouraging is evidence that polyphenols in olive oil can interact with a hereditary
gene variant of endothelial nitric oxide
synthase (the NOS3 Glu298Asp polymorphism, which is a risk factor for hypertension and coronary artery disease), to improve endothelial function after meals.19 So, even if genetics are not in your favor, olive oil may help.»
Second, curcumin helps stimulate a very important genetic pathway known as the NRF2 pathway, which activates a whole set of antioxidant
genes, including
genes like glutathione
synthase (which is the body's natural way of making glutathione) and glutathione peroxidase (which is the way the body uses glutathione to fight off damage) and is just one way that curcumin fights damaging oxidants.