Sentences with phrase «gnca sequences studied»

The scientists make clear that their sequencing studies may have missed mutations in some of the samples.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

The article constitutes the largest sequencing study to date on the genes of representatives from eight sponge genera covering all four currently recognized sponge classes.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

The research team from the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying fungi.

As part of ENCODE, 32 institutions did computer analyses, biochemical tests, and sequencing studies on 147 cell types — six fairly extensively — to find out what each of the genome's 3 billion bases does.

Many of the variants involved in numerous types of cancer have been identified with genetic sequencing studies of large numbers of patients.

«They're doing 50 genes rather than a whole exome» for a gene sequencing study.

700 billion DNA sequences The study was published in the scientific journal Nature Communications.

«There has to be a functional way of assessing the role of these cancer - gene candidates as they appear in sequencing studies,» Sanchez - Rivera says.

This $ 240 million initiative aims to sequence 200,000 genomes over the next four years, making it among the largest sequencing studies in the world.

The CCDG award, when viewed in the light of the recent NIH budget increase, also presents a unique opportunity to seek funding for other large - scale common disease sequencing studies that might be co-funded with other institutes.

You can take just about any gene from a sequencing study or GWAS and — with the assistance of a nice resource like Gene Cards — come up with a story that might connect mutations / variants in that gene to your phenotype of choice.

We also worked with Sam Stanley on a targeted sequencing study to characterize the immunogenetics of smallpox vaccination.

The freely - available software package, MendelScan, is designed to help researchers score and prioritize candidate variants in family exome sequencing studies of Mendelian disease.

Other sequencing studies have illustrated the critical role soil microbes play in breaking down pollutants.

It's the kind of cohort that genetics researchers are currently salivating over, especially in the era of large - scale sequencing studies.

As a result, we're seeing exome and genome sequencing studies published all over the place, not just in genetics / genomics journals but also many that focus on specific tissues (e.g. blood) or diseases (e.g. cancer, metabolic diseases, vision disorders, you name it).

We believe that this is an important advantage for conducting large - scale whole sequence studies over the next couple of years,» said Kari Stefansson, CEO of deCODE.

In their paper published in the journal Science Advances, the team describes their sequencing study of three types of plants and the comparisons they made with other plants that had been previously sequenced, and why they believe that what they found might help such trees survive as the planet warms.

While this sequencing study was underway, the infection control team identified a new case of MRSA carriage in the Special Care Baby Unit, which occurred 64 days after the last MRSA - positive patient had left the same unit.

As a follow - up to my previous post, Disease - causing Mutations Discovered by NGS in 2011, I've attempted to compile cancer genome and exome sequencing studies published last year.

In the new study, the lab has conducted the first large - scale whole genome sequencing study of asthma drug response in African Americans and Latino children in an effort to pin down the genetic factors contributing to reduced albuterol response more precisely than possible in previous association studies.

Several whole - genome sequencing studies of cancer were published last year.

The literature is afloat in «little hits» from GWAS and / or exome sequencing studies.

Exome sequencing studies of several...

Melanoma was another cancer type surveyed by multiple exome sequencing studies in 2011.

In exome sequencing studies of Mendelian disorders, any variant already present in dbSNP was usually common, and therefore unlikely to cause rare genetic diseases.

All seven were located in or near complement genes (that's «complement» as in the innate immune system complex), which had been implicated in AMD by sequencing studies over the past couple of years.

At Johns Hopkins University and Washington University in St. Louis, Dr. Lin was part of one of the first clinical genomics laboratories to lead the computational analyses of the first ever genome sequencing studies (including breast, colorectal, glioblastoma, medulloblastoma, melanoma, and pancreatic).

Within this consortium, she has conducted genome - wide association scans for over 75,000 participants and has undertaken one of the first large - scale whole - genome sequencing studies for colorectal cancer, sequencing the whole genomes of 2,000 patients with colorectal cancer and 1,000 healthy control participants.

The role of heredity in obesity appears to be between 40 and 70 percent, and next - generation sequencing studies of whole genomes (GWAS) have uncovered about 100 common genetic variants that explain a small amount of variation leading to obesity.

All of this points to the heart of the problem with genotyping over sequencing studies: many of the most interesting classes of variation are overlooked.

Group - based variant calling leveraging next - generation supercomputing for large - scale whole - genome sequencing studies.

An exome sequencing study of Moebius syndrome including atypical cases reveals an individual with CFEOM3A and amutation.

In particular, genome - wide sequencing studies have detected somatic mutations in one or more Eph receptors in 25 % -45 % of melanomas, 15 % -45 % of lung cancers, 25 - 40 % of colorectal cancers and 12 % -25 % of head and neck and uterine cancers (Figure 2), but very limited information is available on the effects of the mutations.

I'm also the lead developer of VarScan, an open - source tool for germline and somatic variant calling in NGS data, and MendelScan, an open - source tool for prioritizing variants in family - based sequencing studies.

The sequencing studies, reported in the December 16, 1999, issue of the journal Nature, provide a great deal of new information about chromosome structure, evolution, and gene organization in plants.

: Researchers Present Latest Genome Sequencing Study Findings at ASHG 2009 Meeting ASHG Press Release — October 21, 2009

While whole genome sequencing studies have failed to identify coding mutations in 40 % of the cases, there is evidence from recent efforts to annotate the non-coding sequence that over 80 % of the genome is biochemically active.

Here, we present the largest sequencing study of osteosarcoma to date, comprising 112 childhood and adult tumours encompassing all major histological subtypes.

We detected a burden of very rare, damaging missense variants in known Crohn's disease risk genes, suggesting that more comprehensive sequencing studies will continue to improve understanding of the biology of complex diseases.

These studies, however, were based on comparing Life Technologies» SOLiD and Illumina's GAII with pyrosequencing or Sanger sequencing [8], [9], [10], the costs of which are prohibitive for whole - genome sequencing studies in mammals.

Recent technological advances have enabled genome - wide association studies and emerging next - generation sequencing studies to begin to decipher the nature of the heritable contribution to traits and disease.

A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases.

The distribution of mutant genes was roughly consistent with expectations based on previous exome - wide sequencing studies of BCs (Cancer Genome Atlas Research Network, 2014).

Katherine Meurs, DVM, PhD (Diplomate ACVIM Cardiology) at North Carolina State College of Veterinary Medicine initiated a genome sequencing study in 2015 to try and locate genetic markers for this disease in the Persian breed in the hope that a genetic test might be established.

From Fibonacci sequence studies of television channels to testing couple compatibility through fruit and vegetable shakes, do it makes use of an assortment of random and non-traditional objects to create art.

Bridget Riley, Turquoise and Red Greys, Sequence Study, 1967.

Not exact matches

They also don't share the same DNA because studies have found that identical twins can have different DNA sequences.