Sentences with phrase «grb10 nonfunctional»

You might know that there are three types of patents: utility (protection for new, nonobvious inventions), design (a design that is new but nonfunctional), and plant (covering asexually reproducing flora).

The Supreme fries are a bit more difficult to eat, as the toppings overload can turn the crisp fries nonfunctional and soggy.

Equally impressive, it also installed and ran perfectly on an eccentric four - year - old Sony Vaio laptop that's crash - prone under Windows Me and nonfunctional under Windows XP.

The book's subtitle explains what the author means by the nonfunctional: «Ruins, Relics, Rarities, Rubbish, Uninhabited Places, and Hidden Treasures.»

Seven of Orlando's categories of the nonfunctional in literature developed in the eighteenth or nineteenth century.

Orlando isolates twelve types of writing about the nonfunctional, each of them deriving from one of the bifurcating branches of a neat semantic tree.

For Orlando, the odd prominence of the nonfunctional in Western literature after the late eighteenth century signals a Freudian «return of the repressed.»

Once the reader understands that those hyphenated pairs of adjectives name categories in his quirky taxonomy of nonfunctional objects in literature, and once one learns what those categories entail, the going gets easier.

Psuedogenes are remnants of genes that once served a purpose in our genome that they no longer fulfil, because of mutations that have rendered the genes nonfunctional, i.e., they no longer lead to the production of proteins (long chains of amino acids) that once contributed to specific characteristics in ancient ancestors.

E.g., nonfunctional nostrils in gannets and other members of the family Sulidae.

Although Professor Behe is adamant in his definition of irreducible complexity when he says a precursor «missing a part is by definition nonfunctional,» what he obviously means is that it will not function in the same way the system functions when all the parts are present.

Not only can they be stained and icky, crumbs and liquids can find their way into moving parts, making things nonfunctional.

I have found that even my Fuzzibunz Totes that have nonfunctional zippers still work great as long as I just roll up the bag instead of zipping it shut.

Today New York is a laughingstock because of its chronically dysfunctional legislature and its recent nonfunctional governors.

So the hypothesis might be that if that gene were absent or nonfunctional, the hand would not develop.

In the malady, a victim's immune system attacks hormone - producing organs such as the pancreas and the thyroid, parathyroid, and adrenal glands, often rendering them nonfunctional.

In further test tube experiments, the researchers treated the immortalized white blood cells with both chemical and genetic blockers, called small interfering RNA (siRNA), designed to render either p70S6K or GRB10 nonfunctional.

The team spliced a nonfunctional gene for the ethylene receptor, taken from a common laboratory plant called Arabidopsis, into petunias.

But infected cells can reach such high numbers that the progression to cancer is not terminated by the many mutations that kill the cells or make them nonfunctional.

You start with a kind of memory impairment where you forget where you put your car keys, but you end up with somebody completely nonfunctional, unable to speak or recognize their own kids.

DNA INVESTIGATION Geneticists examined DNA from more than 10,000 people in Pakistan looking for people in whom both copies of certain genes were nonfunctional.

High rates of marriage between closely related people there make it more likely that people will inherit two nonfunctional gene copies.

But many prosthetic hands are still simple nonfunctional devices that are mainly cosmetic.

The number of individuals with nonfunctional rods and cones that still have the ability to sense light is likely «vanishingly small,» he says.

people who carry two nonfunctional copies of one of the roughly 20,000 human genes.

Iceland's genomes also yielded a bounty of so - called human knockouts — people who carry two nonfunctional copies of one of the roughly 20,000 human genes.

According to sensor readings, the flaps effectively removed sweat from the body and lowered skin temperature, more so than when participants wore a similar running suit with nonfunctional flaps.

The researchers were amazed by this latter outcome, as intentional movement requires information to travel from the brain down to the lower spinal cord, a path that had been rendered nonfunctional by his injury.

By comparing the armadillo gene to other closely related mammals, a team of scientists has now identified several cone - related genes in the armadillo genome that became nonfunctional millions of years ago, they report today at the Society for Neuroscience conference in San Diego, California.

They produced AvrBsT in different regions of tobacco leaves along with SOBER1 and several mutated (and thus nonfunctional) versions of the enzyme.

Chemical biologists led by Dana - Farber's Nathanael Gray, PhD, designed and custom - made a compound called THZ1 that forms a particularly strong bond with CDK7, rendering the protein essentially nonfunctional.

Bacteria stay perfectly intact too — except that they are quite dead, because the pressure contorts their DNA and proteins into nonfunctional shapes.

Researchers also hope to gather information on healthy people who have mutations in both copies of a gene that make it nonfunctional.

In addition to becoming immortal, cancer cells invade the surrounding tissue, rendering it nonfunctional.

Reporting online this week in Nature Genetics, the team says it uncovered nine genes, each of which, when nonfunctional, causes XLMR.

A human - specific gene expressed only in glial cells of the brain apparently arose from conversion of the ancestral gene by a nonfunctional pseudogene in a common human chimp ancestor.

We identified human X-linked genes whose gametologs have been pseudogenized or completely lost from the Y chromosome and inferred which evolutionary forces may be acting to retain genes on the Y. Although gene loss appears to be largely correlated with the suppression of recombination, we observe that X-linked genes with functional Y homologs evolve under stronger purifying selection and are expressed at higher levels than X-linked genes with nonfunctional Y homologs.

Additionally, we support and expand upon the hypothesis that X inactivation is primarily driven by gene loss on the Y. Using linear discriminant analysis, we show that X-inactivation status can successfully classify 90 % of X-linked genes into those with functional or nonfunctional Y homologs.

They found a nonfunctional Mhc pseudogene embedded in the region they had sequenced but have yet to find a functional Mhc gene in the finches.

Because humans have a limited capacity for heart tissue regeneration, damaged heart muscle is normally replaced with a nonfunctional scar.

Unfortunately, accumulated misfolded and nonfunctional (dark) fluorescent proteins can not be ignored.

One of these cancer targets is a so - called «nonsense» protein, a nonfunctional protein that is the result of a misread DNA sequence.

It's widely known that many East Asians have a mutation in a related gene that renders this pathway nonfunctional.

Vomeronasal receptor (A) and olfactory receptor genes (B) annotated as functional (black) are expressed at significantly higher levels than those annotated as nonfunctional pseudogenes (grey).

The nucleus - encoded factor MCD4 participates in degradation of nonfunctional 3 «UTR sequences generated by cleavage of pre-mRNA in Chlamydomonas chloroplasts

We have found that some molecules misdirect capsid assembly, presumably by distorting the dimer geometry, giving rise to the rapid production of misshapen and nonfunctional structures.

Afflicted children of the Keshan province succumbed to cardiac failure with a dilated, nonfunctional heart, also called cardiomyopathy.

My obsession with everything chest in high school, particularly the Bench Press, led me to a very nonfunctional physique.

... «Some nodules have been shown to take up a radionuclide precursor in steroid biosynthesis and are hence nonhyperfunctional rather than nonfunctional.

It is a condition that at times has left me paralyzed and almost completely nonfunctional.