Sentences with phrase «gvhd target organs»

As a result, they survive to cross the gastrointestinal lining, enter the bloodstream, and go to target organs, causing allergic reactions throughout the body.

The system can be adapted to target any organ, and the process takes about 14 seconds per fish.

In rheumatoid arthritis, we've never gone to the target organ.»

«They provide unique, biocompatible platforms for wireless delivery of light to virtually any targeted organ in the body,» he said.

It's also a great target organ because it's small and enclosed.

The work, recently published in Science Magazine, reveals the details of how the malaria parasite invades its initial target organ, the liver.

With millions of possible combinations, identifying the optimal nanoparticles to target each organ has been overwhelming.

Contrast agents that exert a strong effect are said to have high «relaxivity,» which enhances the visual contrast between the target organ and surrounding tissue.

To induce cancer mutations, the investigators package the genes for Cas9 and the RNA guide strand into viruses called lentiviruses, which are then injected into the target organs of adult mice.

Is it the case that the red cells would be expected to reach target organs faster than unattached drugs in the bloodstream?

Researchers will now study how these different types of messengers develop, exactly what molecules each of them carry, and what their functions are at their target organ sites.

To deliver the genes for Cas9 and the RNA guide strand, the MIT team packaged them into viruses called lentiviruses, which can be injected into the target organs of adult mice.

In the first half of this century the new science of experimental embryology seemed to offer the best way to study the intimate bond that interlocks the growth of the peripheral neurons and their target organs.

In addition to apparently being essential to the survival of immature sympathetic neurons NGF seems to play a vital role in guiding nerve fibers toward their corresponding target organs.

This finding implies that the tip of a growing sympathetic nerve fiber elongates along a diffusion gradient of NGF released by the target organ.

Regardless of the targeted organ for cell replacement or regeneration, the shared challenges in cell therapies for diabetes such as transplant procedure and immune rejection will be well - served by the collective expertise within CCTD.

Successful cell replacement depends on the ability of donor cells to differentiate into all functional cell types lost in the target organ.

By secreting SDF - 1, lymphatic vessels guide the metastasis of CXCR4 + / CD133 + melanoma cells towards target organs [40].

Tissues being sampled include biopsy material from target organs, peripheral blood cells and serum / plasma, germline DNA, and stool for microbiota analysis.

In this review, we highlight this technological opportunity by focusing on key target organs associated with drug safety and metabolism.

Intestinal function is especially important as a determinant of fly aging and mortality, and many exploratory interventions target this organ.

A recent observational study investigating sex differences in target organ damage, in insulin - resistant patients, demonstrated increased vascular and renal damage in women, who had increased intima - media thickness progression, higher numbers of vascular plaques, and reduced pulse wave velocity compared with men (321).

Gender differences in the progression of target organ damage in patients with increased insulin resistance: the LOD - DIABETES study

We performed histological examination of GVHD target organs (liver, lung, small intestine, and colon) and the tongue, which served as a surrogate for skin damage (37), 4 wk after transplantation.

«With the chicken embryo, we can look at a very wide range of developmental stages, and we can identify potential target organs.

The infiltration of Th1 and Th17 cells into GVHD target organs (liver and lung), as well as the serum level of related cytokines, also were increased in allogeneic BMT recipients.

Moreover, the infiltration of Th1 and Th17 cells into GVHD target organs, as well as the serum level of proinflammatory cytokines, were significantly decreased.

On the other hand, if you're looking for targeted organ or glandular support, you may be interested in our GRASS FED BEEF HEART to support a strong heart (or) our GRASS FED THYROID for thyroid support... you get the picture.

gentle non-invasive form of therapy that targets the organs and their surrounding tissues including ligaments, fascia and membranes.

On the other hand, if you're looking for targeted organ support, you may be interested in our GRASS FED BEEF HEART to support heart health (or) our GRASS FED THYROID to support a struggling thyroid (or) our GRASS FED THYMUS to support thymus function and immune health... you get the picture.

Dendritic cells home to pancreatic and mesenteric lymph nodes and present gliadin, leading to «migration of CD4 − CD8 − γδ and CD4 − CD8 + αβ T cells to the target organ (gut and / or pancreas) where they cause inflammation» (Fasano, 2011).

On the other hand, if you're looking for targeted organ support, you may be interested in our GRASS FED BEEF HEART to support heart health (or) our GRASS FED THYROID to support thyroid health... you get the picture.

This theory proposes that an infection inside the actual target organ leads the immune system to attack the «home» of the infection.

On the other hand, if you're looking for targeted organ support, you may be interested in our GRASS FED BEEF HEART to support heart health (or) our GRASS FED THYROID to support a struggling thyroid (or) our GRASS FED SPLEEN to support spleen and immune health... you get the picture.

Based on Dr. Fasano's research, the same approach should apply to all autoimmune conditions, although triggers may be different for the particular target organ that is affected.

First, despite the fact that the work of educators targets the organ of learning, the brain, most teachers and school leaders have little understanding of the architecture of the brain and how it receives, filters, and applies information.

The skin appears to be the primary target organ for these allergies in pets, in humans; the primary target is our respiratory system.

Thus, repeated or prolonged exposure to the substance can produce target organs damage.

A low quality pet food company will use scraps from a rendering plant, including many things that are not digestible, rather than targeted organ meat.

Since these electrical impulses are generated in the neurons and are sent straight to target organs, the abnormal, uncontrollable, and uncoordinated firing of nerve impulses can be readily seen in the said organs.

Distribution through the bloodstream results in infection of other target organs including kidneys, liver, spleen, CNS, & reproductive tract.

The clinical signs of blastomycosis may vary with the target organs affected and may include one or all of the following: anorexia, depression, weight loss, fever (103 degrees or higher) that doesn't respond to antibiotics, coughing, shortness of breath, exercise intolerance, enlarged lymph nodes, eye disease, or skin lesions that drain bloody or purulent material.

According to some sources, prolonged / repeated exposure can cause target organ damage.

It continued: «screening is not done systematically, and the diagnosis is often made at a late stage when target organ damage has already happened».

(This is a phramacokinetic view — if you increase the infusion rate of a drug until a new steady - state has been achieved, you would not necessarily have equal increases in the concentrations in the plasma and in the target organ.)

Not exact matches

I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections in some common surgeries, tackling resistance in targeted antibody drugs, improving gene vectors for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.

Because, as Belmonte rightly explains, the new «precisely targeted» tools can help us «study species evolution, biology and disease, and may lead ultimately to the ability to grow human organs for transplant.»

Pedophiles will target children who don't know the names of sex organs because it's a sign to them that the parents aren't willing to talk openly with their children about sex and are communicating (whether intentionally or not) that it's something to be kept secret or be ashamed about, making it more likely the child will NOT report to or tell the parent that they've been abused.

«We've previously understood very little about how these bacteria move through and into our organs, tissues, and central nervous system, but our work sheds light on these processes and could form the basis for novel therapeutics that target the bacterium's ability to invade.»

The organ donors were assigned after neurologic determination of death to either of two targeted temperatures — 34 - 35 °C (hypothermia) or 36.5 - 37.5 °C (normal body temperature).