Not exact matches
Genetic variation can
take the form of common base changes (polymorphisms) that alter
gene function or rare base changes (mutations) that often have highly deleterious
effects.
Once there, it may activate DNA - destroying enzymes, in
effect taking molecular scissors to the strands of
genes, snipping them to bits.
They found that people with the
gene variant had the highest risk of side
effects when they were given a statin called simvastatin, but this risk was much lower when they
took pravastatin.
«It's important they've found this
gene, but it
took a sample of 20,000 people to find it, precisely because the
effect is so small,» says Robert Plomin at the Institute of Psychiatry in London, and lead author of a groundbreaking study in 2007 which failed to find any single
genes of disproportionate importance in intelligence.
One person
takes a drug and has a set of side
effects, all of which could involve different
genes.
But it has not been clear until now that the
effects of these particular
gene variations can vary by race in patients
taking clopidogrel after a heart attack.
The study further suggests that NSAIDs such as aspirin, ibuprofen and naproxen have a particularly advantageous
effect when
taken after diagnosis by colorectal, or CRC, patients without tumor mutation in the KRAS
gene (KRAS wild - type tumors): The study shows that NSAID use by this group is associated with a survival benefit of 40 percent.
These assessments, which
take into account the
gene drive's characteristics,
effects on humans and the environment, and local values and governance, are a key tool for determining a
gene drive's impacts.
We find that many
genes change expression over relatively short PMIs in a tissue - specific manner, but this potentially confounding
effect in a biological analysis can be minimized by
taking into account appropriate covariates.
The researchers were able to predict the direction of this
effect with high accuracy, based on the sequences of bacteria present and the resistance
genes they carried in samples
taken before treatment.
Is the strange and beautiful Dr Carijona friend or foe?After a frantic breakout, Kiel Helsteen tears over the Andes and through the rain forest, desperate to uncover the truth, tell the world and save his friends.Pursued by the inventors and their ruthless henchmen, can he sabotage their work before the
effects of the Prestin
gene take hold?
Downward trends in popular breeds
take several years to affect the
gene pool, but big year to year changes in rare breeds can have a devastating
effect.
The sculptures and photographs by Elaine Bradford and the works on paper by Megan Greene
take Darwin's theory of phenotype (or the visible characteristics of an animal that result from the combined
effects of the
genes and the environment) even further by incorporating human fashion and adornment as a means for a species to adapt to its surroundings.
Writing in 1970,
Gene Youngblood advocated that artists
take up the technologies of the moment — special
effects, computer art, video art, multi-media environments, and holography — to expand the consciousness of their publics.